國立虎尾科技大學 |

Study of the peptide-peptide and peptide-protein interactions and their applications in cell imaging and nanoparticle surface modification

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Study of the peptide-peptide and peptide-protein interactions and their applications in cell imaging and nanoparticle surface modification/ by Jianpeng Wang.
Author:	Wang, Jianpeng.
Published:	Berlin, Heidelberg :Springer Berlin Heidelberg : : 2016.,
Description:	xiii, 96 p. :ill. (some col.), digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	Peptides. -
Online resource:	http://dx.doi.org/10.1007/978-3-662-53399-4
ISBN:	9783662533994

Study of the peptide-peptide and peptide-protein interactions and their applications in cell imaging and nanoparticle surface modification
Wang, Jianpeng.

Study of the peptide-peptide and peptide-protein interactions and their applications in cell imaging and nanoparticle surface modification[electronic resource] /by Jianpeng Wang. - Berlin, Heidelberg :Springer Berlin Heidelberg :2016. - xiii, 96 p. :ill. (some col.), digital ;24 cm. - Springer theses,2190-5053. - Springer theses..

Introduction -- Biological Active Antifungal Peptides -- Protein Ligands Engineering -- Coiled Coil Binding Induced Covalent Cross-linking -- Cell Surface Receptor Labeling -- Summary and Conclusion.

This thesis focuses on the study of interactions between protein and peptides and their potential applications in cell imaging and nanoparticle surface modification. Drawing inspiration from naturally occurring coiled-coil binding pairs, it proposes a novel covalent peptide tag and probe system, based on the concept of "affinity guided covalent conjugation." This newly established methodology provides complementary resolution to protein labeling, imaging and trafficking. By systematically investigating the coordination interaction between protein and quantum dots using various engineered protein ligands, this thesis proposes a general rule for protein self-assembly on the surface of quantum dots and reports a revolutionized nanobelt protein in accordance with this rule. It is an extraordinary example of interdisciplinary research, providing answers to real-life biological problems from a chemistry perspective.

ISBN: 9783662533994

Standard No.: 10.1007/978-3-662-53399-4doiSubjects--Topical Terms:

673783
Peptides.

LC Class. No.: QD431

Dewey Class. No.: 572.65

Study of the peptide-peptide and peptide-protein interactions and their applications in cell imaging and nanoparticle surface modification
LDR:02211nam a2200325 a 4500 001 866902
003 DE-He213
005 20160926101255.0
006 m d
007 cr nn 008maaau
008 170720s2016 gw s 0 eng d
020 $a 9783662533994 $q (electronic bk.)
020 $a 9783662533970 $q (paper)
024 7 $a 10.1007/978-3-662-53399-4 $2 doi
035 $a 978-3-662-53399-4
040 $a GP $c GP
041 0 $a eng
050 4 $a QD431
072 7 $a TCB $2 bicssc
072 7 $a SCI010000 $2 bisacsh
082 0 4 $a 572.65 $2 23
090 $a QD431 $b .W246 2016
100 1 $a Wang, Jianpeng. $3 1113431
245 1 0 $a Study of the peptide-peptide and peptide-protein interactions and their applications in cell imaging and nanoparticle surface modification $h [electronic resource] / $c by Jianpeng Wang.
260 $a Berlin, Heidelberg : $c 2016. $b Springer Berlin Heidelberg : $b Imprint: Springer,
300 $a xiii, 96 p. : $b ill. (some col.), digital ; $c 24 cm.
490 1 $a Springer theses, $x 2190-5053
505 0 $a Introduction -- Biological Active Antifungal Peptides -- Protein Ligands Engineering -- Coiled Coil Binding Induced Covalent Cross-linking -- Cell Surface Receptor Labeling -- Summary and Conclusion.
520 $a This thesis focuses on the study of interactions between protein and peptides and their potential applications in cell imaging and nanoparticle surface modification. Drawing inspiration from naturally occurring coiled-coil binding pairs, it proposes a novel covalent peptide tag and probe system, based on the concept of "affinity guided covalent conjugation." This newly established methodology provides complementary resolution to protein labeling, imaging and trafficking. By systematically investigating the coordination interaction between protein and quantum dots using various engineered protein ligands, this thesis proposes a general rule for protein self-assembly on the surface of quantum dots and reports a revolutionized nanobelt protein in accordance with this rule. It is an extraordinary example of interdisciplinary research, providing answers to real-life biological problems from a chemistry perspective.
650 0 $a Peptides. $3 673783
650 0 $a Bioconjugates. $3 654769
650 1 4 $a Chemistry. $3 593913
650 2 4 $a Biotechnology. $3 554955
650 2 4 $a Protein Science. $3 782127
650 2 4 $a Nanotechnology. $3 557660
650 2 4 $a Bioorganic Chemistry. $3 677511
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer eBooks
830 0 $a Springer theses. $3 831604
856 4 0 $u http://dx.doi.org/10.1007/978-3-662-53399-4
950 $a Chemistry and Materials Science (Springer-11644)