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Biological Applications of Extraordinary Electroconductance and Photovoltaic Effects in Inverse Extraordinary Optoconductance.

Record Type:	Language materials, manuscript : Monograph/item
Title/Author:	Biological Applications of Extraordinary Electroconductance and Photovoltaic Effects in Inverse Extraordinary Optoconductance./
Author:	Tran, Lauren Christine.
Description:	1 online resource (180 pages)
Notes:	Source: Dissertation Abstracts International, Volume: 74-10(E), Section: B.
Subject:	Physics. -
Online resource:	click for full text (PQDT)
ISBN:	9781303242069

Biological Applications of Extraordinary Electroconductance and Photovoltaic Effects in Inverse Extraordinary Optoconductance.
Tran, Lauren Christine.

Biological Applications of Extraordinary Electroconductance and Photovoltaic Effects in Inverse Extraordinary Optoconductance. - 1 online resource (180 pages)

Source: Dissertation Abstracts International, Volume: 74-10(E), Section: B.

Thesis (Ph.D.)--Washington University in St. Louis, 2013.

Includes bibliographical references

The Extraordinary Electroconductance (EEC) sensor has been previously demonstrated to have an electric field sensitivity of 3.05V/cm in a mesoscopic-scale structure fabricated at the center of a parallel plate capacitor. In this thesis, we demonstrate the first successful application of EEC sensors as electrochemical detectors of protein binding and biological molecule concentration. Using the avidin derivative, captavidin, in complex with the vitamin biotin, the change in four-point measured resistance with fluid protein concentration of bare EEC sensors was shown to increase by a factor of four in the presence of biomolecular binding as compared to baseline. Calculations for approximate field strengths introduced by a bound captavidin molecule are also presented.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2018

Mode of access: World Wide Web

ISBN: 9781303242069Subjects--Topical Terms:

564049
Physics.
Index Terms--Genre/Form:

554714
Electronic books.

Biological Applications of Extraordinary Electroconductance and Photovoltaic Effects in Inverse Extraordinary Optoconductance.
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100 1 $a Tran, Lauren Christine. $3 1148719
245 1 0 $a Biological Applications of Extraordinary Electroconductance and Photovoltaic Effects in Inverse Extraordinary Optoconductance.
264 0 $c 2013
300 $a 1 online resource (180 pages)
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500 $a Source: Dissertation Abstracts International, Volume: 74-10(E), Section: B.
500 $a Adviser: Stuart A. Solin.
502 $a Thesis (Ph.D.)--Washington University in St. Louis, 2013.
504 $a Includes bibliographical references
520 $a The Extraordinary Electroconductance (EEC) sensor has been previously demonstrated to have an electric field sensitivity of 3.05V/cm in a mesoscopic-scale structure fabricated at the center of a parallel plate capacitor. In this thesis, we demonstrate the first successful application of EEC sensors as electrochemical detectors of protein binding and biological molecule concentration. Using the avidin derivative, captavidin, in complex with the vitamin biotin, the change in four-point measured resistance with fluid protein concentration of bare EEC sensors was shown to increase by a factor of four in the presence of biomolecular binding as compared to baseline. Calculations for approximate field strengths introduced by a bound captavidin molecule are also presented.
520 $a The development of Inverse-Extraordinary Optoconductance (I-EOC), an effect which occurs in nanoscale sensors, is also discussed. In the I-EOC effect, electron transport transitions from ballistic to diffusive with increasing light intensity. In these novel, room temperature optical detectors, the resistance is low at low light intensity and resistance increases by 9462% in a 250nm device mesa upon full illumination with a 5 mW HeNe laser. This is the inverse of bulk and mesoscopic device behavior, in which resistance decreases with increasing photon density.
533 $a Electronic reproduction. $b Ann Arbor, Mich. : $c ProQuest, $d 2018
538 $a Mode of access: World Wide Web
650 4 $a Physics. $3 564049
650 4 $a Biophysics. $3 581576
655 7 $a Electronic books. $2 local $3 554714
690 $a 0605
690 $a 0786
710 2 $a ProQuest Information and Learning Co. $3 1178819
710 2 $a Washington University in St. Louis. $b Physics. $3 845429
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3587181 $z click for full text (PQDT)