國立虎尾科技大學 |

Therapeutic Proteins Against Human Diseases

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Therapeutic Proteins Against Human Diseases/ edited by Fahmida Khatoon Zahid Balouch.
other author:	Zahid Balouch, Fahmida Khatoon.
Description:	IX, 173 p. 1 illus.online resource. :
Contained By:	Springer Nature eBook
Subject:	Therapeutics. -
Online resource:	https://doi.org/10.1007/978-981-16-7897-4
ISBN:	9789811678974

Therapeutic Proteins Against Human Diseases
Therapeutic Proteins Against Human Diseases[electronic resource] /edited by Fahmida Khatoon Zahid Balouch. - 1st ed. 2022. - IX, 173 p. 1 illus.online resource.

Proteins drug targeting and its therapeutics -- Interferons -- Epidermal growth factor (egf) in wound repair -- Therapeutic protein against autoimmune disorders: Intracellular and extracellular properties -- Prions as Therapeutic proteins and their Prospect as Drug Delivery Agent -- INTERLEUKIN - 2 -- Bioinformatics resources, tools, and strategies in designing therapeutic proteins -- Therapeutic proteins used in human pancreatic disease -- Therapeutic role of soybean-derived lunasin peptide in colon cancer treatment: A recent updates from literature -- Therapeutic peptides in skin and hair disorders. .

This book compiles updated research about the implications of therapeutic proteins in various human diseases. The initial chapters of the book provide basic information on the therapeutic proteins and discuss techniques for their formulation, production, and analytic approaches for their characterization. The subsequent chapters shed light on therapies based on therapeutic proteins against metabolic disorders, neurological disorders, cancer, autoimmune disorders, and infectious diseases. Importantly, it presents the factors influencing the immunogenicity of therapeutic proteins, including, genetic factors, disease type, and origin of therapeutic protein, dose frequency, administration route, and treatment duration. The book also reviews the strategies for reducing immunogenicity associated with therapeutic proteins, including PEGylation, site specific mutagenesis, exon shuffling, and humanizing of monoclonal antibodies. Further, it presents strategies for improving the typical drawback associated with protein therapeutics including instability and limited penetration through biological barriers. This book covers various computational methods that are commonly used for designing therapeutic proteins and in silico method for predicting and improving in vivo efficacy of the therapeutic molecules. Lastly, the book highlights the recent advances in developing nanosized delivery systems to improve safety and efficacy of protein therapeutics. This book caters to students and researchers of medicinal chemistry, pharmaceutical sciences and therapeutics. It is also useful to clinicians working with therapeutic proteins.

ISBN: 9789811678974

Standard No.: 10.1007/978-981-16-7897-4doiSubjects--Topical Terms:

644915
Therapeutics.

LC Class. No.: RM1-950

Dewey Class. No.: 615.5

Therapeutic Proteins Against Human Diseases
LDR:03610nam a22004215i 4500 001 1083719
003 DE-He213
005 20220928113644.0
007 cr nn 008mamaa
008 221228s2022 si | s |||| 0|eng d
020 $a 9789811678974 $9 978-981-16-7897-4
024 7 $a 10.1007/978-981-16-7897-4 $2 doi
035 $a 978-981-16-7897-4
050 4 $a RM1-950
072 7 $a MMZ $2 bicssc
072 7 $a MJC $2 bicssc
072 7 $a PSY028000 $2 bisacsh
072 7 $a MKZ $2 thema
072 7 $a MJC $2 thema
082 0 4 $a 615.5 $2 23
245 1 0 $a Therapeutic Proteins Against Human Diseases $h [electronic resource] / $c edited by Fahmida Khatoon Zahid Balouch.
250 $a 1st ed. 2022.
264 1 $a Singapore : $b Springer Nature Singapore : $b Imprint: Springer, $c 2022.
300 $a IX, 173 p. 1 illus. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
505 0 $a Proteins drug targeting and its therapeutics -- Interferons -- Epidermal growth factor (egf) in wound repair -- Therapeutic protein against autoimmune disorders: Intracellular and extracellular properties -- Prions as Therapeutic proteins and their Prospect as Drug Delivery Agent -- INTERLEUKIN - 2 -- Bioinformatics resources, tools, and strategies in designing therapeutic proteins -- Therapeutic proteins used in human pancreatic disease -- Therapeutic role of soybean-derived lunasin peptide in colon cancer treatment: A recent updates from literature -- Therapeutic peptides in skin and hair disorders. .
520 $a This book compiles updated research about the implications of therapeutic proteins in various human diseases. The initial chapters of the book provide basic information on the therapeutic proteins and discuss techniques for their formulation, production, and analytic approaches for their characterization. The subsequent chapters shed light on therapies based on therapeutic proteins against metabolic disorders, neurological disorders, cancer, autoimmune disorders, and infectious diseases. Importantly, it presents the factors influencing the immunogenicity of therapeutic proteins, including, genetic factors, disease type, and origin of therapeutic protein, dose frequency, administration route, and treatment duration. The book also reviews the strategies for reducing immunogenicity associated with therapeutic proteins, including PEGylation, site specific mutagenesis, exon shuffling, and humanizing of monoclonal antibodies. Further, it presents strategies for improving the typical drawback associated with protein therapeutics including instability and limited penetration through biological barriers. This book covers various computational methods that are commonly used for designing therapeutic proteins and in silico method for predicting and improving in vivo efficacy of the therapeutic molecules. Lastly, the book highlights the recent advances in developing nanosized delivery systems to improve safety and efficacy of protein therapeutics. This book caters to students and researchers of medicinal chemistry, pharmaceutical sciences and therapeutics. It is also useful to clinicians working with therapeutic proteins.
650 0 $a Therapeutics. $3 644915
650 0 $a Diseases. $3 636013
650 0 $a Pharmacology. $3 583819
650 0 $a Clinical biochemistry. $3 591508
650 0 $a Proteins . $3 1253493
650 2 4 $a Medical Biochemistry. $3 668897
650 2 4 $a Protein Biochemistry. $3 1387915
700 1 $a Zahid Balouch, Fahmida Khatoon. $e editor. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1389811
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9789811678967
776 0 8 $i Printed edition: $z 9789811678981
776 0 8 $i Printed edition: $z 9789811678998
856 4 0 $u https://doi.org/10.1007/978-981-16-7897-4
912 $a ZDB-2-SME
912 $a ZDB-2-SXM
950 $a Medicine (SpringerNature-11650)
950 $a Medicine (R0) (SpringerNature-43714)