國立虎尾科技大學 |

Antimalarial Natural Products

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Antimalarial Natural Products/ edited by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch.
other author:	Kinghorn, A. Douglas.
Description:	IX, 106 p. 112 illus., 8 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Natural products. -
Online resource:	https://doi.org/10.1007/978-3-030-89873-1
ISBN:	9783030898731

Antimalarial Natural Products
Antimalarial Natural Products[electronic resource] /edited by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch. - 1st ed. 2022. - IX, 106 p. 112 illus., 8 illus. in color.online resource. - Progress in the Chemistry of Organic Natural Products,1172192-4309 ;. - Progress in the Chemistry of Organic Natural Products,100.

This volume begins with a short history of malaria and follows with a summary of its biology. It then traces the fascinating history of the discovery of quinine for malaria treatment, and then describes quinine’s biosynthesis, its mechanism of action, and its clinical use, concluding with a discussion of synthetic antimalarial agents based on quinine’s structure. It also covers the discovery of artemisinin and its development as the source of the most effective current antimalarial drug, including summaries of its synthesis and biosynthesis, its mechanism of action, and its clinical use and resistance. A short discussion of other clinically used antimalarial natural products leads to a detailed treatment of additional natural products with significant antiplasmodial activity, classified by compound type. Although the search for new antimalarial natural products from Nature’s combinatorial library is challenging, it is very likely to yield new antimalarial drugs. This book thus ends by identifying ten natural products with development potential as clinical antimalarial agents.

ISBN: 9783030898731

Standard No.: 10.1007/978-3-030-89873-1doiSubjects--Topical Terms:

568969
Natural products.

LC Class. No.: QD241-441

Dewey Class. No.: 547

Antimalarial Natural Products
LDR:02600nam a22003975i 4500 001 1092092
003 DE-He213
005 20221213182126.0
007 cr nn 008mamaa
008 221228s2022 sz | s |||| 0|eng d
020 $a 9783030898731 $9 978-3-030-89873-1
024 7 $a 10.1007/978-3-030-89873-1 $2 doi
035 $a 978-3-030-89873-1
050 4 $a QD241-441
072 7 $a PNN $2 bicssc
072 7 $a SCI013040 $2 bisacsh
072 7 $a PNN $2 thema
082 0 4 $a 547 $2 23
245 1 0 $a Antimalarial Natural Products $h [electronic resource] / $c edited by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch.
250 $a 1st ed. 2022.
264 1 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2022.
300 $a IX, 106 p. 112 illus., 8 illus. in color. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
490 1 $a Progress in the Chemistry of Organic Natural Products, $x 2192-4309 ; $v 117
520 $a This volume begins with a short history of malaria and follows with a summary of its biology. It then traces the fascinating history of the discovery of quinine for malaria treatment, and then describes quinine’s biosynthesis, its mechanism of action, and its clinical use, concluding with a discussion of synthetic antimalarial agents based on quinine’s structure. It also covers the discovery of artemisinin and its development as the source of the most effective current antimalarial drug, including summaries of its synthesis and biosynthesis, its mechanism of action, and its clinical use and resistance. A short discussion of other clinically used antimalarial natural products leads to a detailed treatment of additional natural products with significant antiplasmodial activity, classified by compound type. Although the search for new antimalarial natural products from Nature’s combinatorial library is challenging, it is very likely to yield new antimalarial drugs. This book thus ends by identifying ten natural products with development potential as clinical antimalarial agents.
650 0 $a Natural products. $3 568969
650 0 $a Medicinal chemistry. $3 1253747
650 0 $a Parasitology. $3 669054
650 0 $a Chemistry, Organic. $3 596209
650 0 $a Pharmaceutical chemistry. $3 581965
650 1 4 $a Natural Products. $3 1366355
650 2 4 $a Medicinal Chemistry. $3 668872
650 2 4 $a Organic Chemistry. $3 673440
650 2 4 $a Pharmaceutics. $3 1366841
700 1 $a Kinghorn, A. Douglas. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 649575
700 1 $a Falk, Heinz. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 796060
700 1 $a Gibbons, Simon. $e editor. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1269908
700 1 $a Asakawa, Yoshinori. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1079863
700 1 $a Liu, Ji-Kai. $e editor. $1 https://orcid.org/0000-0001-6279-7893 $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1282794
700 1 $a Dirsch, Verena M. $e editor. $1 https://orcid.org/0000-0002-9261-5293 $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1357012
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9783030898724
776 0 8 $i Printed edition: $z 9783030898748
776 0 8 $i Printed edition: $z 9783030898755
830 0 $a Progress in the Chemistry of Organic Natural Products, $x 2191-7043 ; $v 100 $3 1254704
856 4 0 $u https://doi.org/10.1007/978-3-030-89873-1
912 $a ZDB-2-CMS
912 $a ZDB-2-SXC
950 $a Chemistry and Materials Science (SpringerNature-11644)
950 $a Chemistry and Material Science (R0) (SpringerNature-43709)