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Biomarkers for Bovine Mammary Gland Involution and Disease.

Record Type:	Language materials, manuscript : Monograph/item
Title/Author:	Biomarkers for Bovine Mammary Gland Involution and Disease./
Author:	Strickland, Jaimie Marie.
Description:	1 online resource (209 pages)
Notes:	Source: Dissertations Abstracts International, Volume: 84-08, Section: B.
Contained By:	Dissertations Abstracts International84-08B.
Subject:	Animal sciences. -
Online resource:	click for full text (PQDT)
ISBN:	9798371989215

Biomarkers for Bovine Mammary Gland Involution and Disease.
Strickland, Jaimie Marie.

Biomarkers for Bovine Mammary Gland Involution and Disease. - 1 online resource (209 pages)

Source: Dissertations Abstracts International, Volume: 84-08, Section: B.

Thesis (Ph.D.)--Michigan State University, 2023.

Includes bibliographical references

Bovine mammary gland involution occurs after the abrupt cessation of lactation and involves a complex sequence of inflammatory processes, morphology changes, and mammary epithelial cell turnover. The mammary gland is vulnerable to bacterial infections in the first 3 weeks after dry off, especially if milk leakage occurs. Increased risk of milk leakage and infection are associated with high milk production at the end of lactation. Therefore, as advances in dairy cow genetics and management continue to increase milk production- more cows will be at risk for infection during early mammary involution. Many aspects of mammary gland involution remain unknown. Biomarkers can be used to predict disease, such as with plasma non-esterified fatty acids in close up dry cows. Biomarkers can also be used to monitor the effect of treatment or intervention. There is not strong evidence that many of the current biomarkers for mammary gland involution, such as lactoferrin, are associated with disease risk or improved involution. Thus, this dissertation is centered around the association of certain biomarkers (fat soluble vitamins and lipid mediators) with mammary gland involution, oxidative stress, and diseases in dairy cows.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2024

Mode of access: World Wide Web

ISBN: 9798371989215Subjects--Topical Terms:

1178863
Animal sciences.
Subjects--Index Terms:

BiomarkerIndex Terms--Genre/Form:

554714
Electronic books.

Biomarkers for Bovine Mammary Gland Involution and Disease.
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500 $a Advisor: Ruegg, Pamela L. ; Sordillo, Lorraine M.
502 $a Thesis (Ph.D.)--Michigan State University, 2023.
504 $a Includes bibliographical references
520 $a Bovine mammary gland involution occurs after the abrupt cessation of lactation and involves a complex sequence of inflammatory processes, morphology changes, and mammary epithelial cell turnover. The mammary gland is vulnerable to bacterial infections in the first 3 weeks after dry off, especially if milk leakage occurs. Increased risk of milk leakage and infection are associated with high milk production at the end of lactation. Therefore, as advances in dairy cow genetics and management continue to increase milk production- more cows will be at risk for infection during early mammary involution. Many aspects of mammary gland involution remain unknown. Biomarkers can be used to predict disease, such as with plasma non-esterified fatty acids in close up dry cows. Biomarkers can also be used to monitor the effect of treatment or intervention. There is not strong evidence that many of the current biomarkers for mammary gland involution, such as lactoferrin, are associated with disease risk or improved involution. Thus, this dissertation is centered around the association of certain biomarkers (fat soluble vitamins and lipid mediators) with mammary gland involution, oxidative stress, and diseases in dairy cows.
533 $a Electronic reproduction. $b Ann Arbor, Mich. : $c ProQuest, $d 2024
538 $a Mode of access: World Wide Web
650 4 $a Animal sciences. $3 1178863
650 4 $a Immunology. $3 592892
653 $a Biomarker
653 $a Dairy cow
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653 $a Mastitis
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