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Circadian Rhythms and Exercise : = Findings from the Central Clock.

Record Type:	Language materials, manuscript : Monograph/item
Title/Author:	Circadian Rhythms and Exercise :/
Reminder of title:	Findings from the Central Clock.
Author:	Marcello, Nicholas A.
Description:	1 online resource (28 pages)
Notes:	Source: Masters Abstracts International, Volume: 83-12.
Contained By:	Masters Abstracts International83-12.
Subject:	Kinesiology. -
Online resource:	click for full text (PQDT)
ISBN:	9798438769910

Circadian Rhythms and Exercise : = Findings from the Central Clock.
Marcello, Nicholas A.

Circadian Rhythms and Exercise :Findings from the Central Clock. - 1 online resource (28 pages)

Source: Masters Abstracts International, Volume: 83-12.

Thesis (M.S.)--University of Wyoming, 2022.

Includes bibliographical references

BACKGROUND INFORMATION/INTRO: Circadian rhythms are the body's biological clock that carries out essential processes. These processes run on a 24-hour cycle which can be disrupted through multiple factors. Disruption of these cycles can lead to a variety of issues including sleep loss, insomnia, changes to mental health, and physical ailments such as cancer, cardiac dysfunction, and sarcopenia. Gene expression in the central clock produces circadian rhythms in the central clock known as the suprachiasmatic nucleus (SCN) as well as in the peripheral tissue. FOS is a neural marker of activity in the SCN METHODS: Four groups of male and female mice (~12 months) were separated into a control group (C), a disrupted and sedentary group (DS), and a disrupted and forced exercise group (DE), and a non-disrupted and forced exercise group (NDE). The circadian disruption (CD) for the DS and DE groups consisted of an accelerated shift work schedule for four weeks. The DE and NDE mice were subjected to forced treadmill running daily at the start of their normal activity period. Immunohistochemistry was completed to observe gene expression in the SCN. RESULTS: A one-way ANOVA revealed a significant between-groups effect (F3,15 = 6.305, P = 0.0056). Post hoc analyses revealed a significant difference between the DNE and NDNE group (P = 0.003). CONCLUSIONS: The CD protocol effectively reduced FOS expression in the SCN. Mice in the DE group displayed increased FOS expression in the SCN that more closely resembled the non-disrupted groups compared to the DNE group.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2024

Mode of access: World Wide Web

ISBN: 9798438769910Subjects--Topical Terms:

721210
Kinesiology.
Subjects--Index Terms:

CircadianIndex Terms--Genre/Form:

554714
Electronic books.

Circadian Rhythms and Exercise : = Findings from the Central Clock.
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