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Interleukin 12 = antitumor activity ...
~
Lasek, Witold.
Interleukin 12 = antitumor activity and immunotherapeutic potential in oncology /
Record Type:
Language materials, printed : Monograph/item
Title/Author:
Interleukin 12/ by Witold Lasek, Radoslaw Zagozdzon.
Reminder of title:
antitumor activity and immunotherapeutic potential in oncology /
Author:
Lasek, Witold.
other author:
Zagozdzon, Radoslaw.
Published:
Cham :Springer International Publishing : : 2016.,
Description:
vii, 75 p. :ill., digital ; : 24 cm.;
Contained By:
Springer eBooks
Subject:
Interleukin-12. -
Online resource:
http://dx.doi.org/10.1007/978-3-319-46906-5
ISBN:
9783319469065
Interleukin 12 = antitumor activity and immunotherapeutic potential in oncology /
Lasek, Witold.
Interleukin 12
antitumor activity and immunotherapeutic potential in oncology /[electronic resource] :by Witold Lasek, Radoslaw Zagozdzon. - Cham :Springer International Publishing :2016. - vii, 75 p. :ill., digital ;24 cm. - SpringerBriefs in immunology,2194-2773. - SpringerBriefs in immunology..
This book discusses the immunotherapeutic potential of Interleukin 12 in the context of clinical oncology, as well as antitumor effects confirmed in preclinical studies and clinical trials in cancer immunotherapy. Due to its ability to activate both innate (NK cells) and adaptive (cytotoxic T lymphocytes) immunities, Interleukin 12 (IL-12) has been regarded as a promising candidate for tumor immunotherapy. However, despite the encouraging results in animal models, only very modest antitumor effects have been confirmed in early clinical trials. Recently, several clinical studies have been initiated in which IL-12 was applied as an adjuvant in cancer vaccines, in gene therapy including locoregional injections of IL-12 plasmid, and in the form of tumor-targeting immunocytokines (IL-12 fused to monoclonal antibodies)
ISBN: 9783319469065
Standard No.: 10.1007/978-3-319-46906-5doiSubjects--Topical Terms:
1113332
Interleukin-12.
LC Class. No.: QR185.8.I56
Dewey Class. No.: 616.079
Interleukin 12 = antitumor activity and immunotherapeutic potential in oncology /
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This book discusses the immunotherapeutic potential of Interleukin 12 in the context of clinical oncology, as well as antitumor effects confirmed in preclinical studies and clinical trials in cancer immunotherapy. Due to its ability to activate both innate (NK cells) and adaptive (cytotoxic T lymphocytes) immunities, Interleukin 12 (IL-12) has been regarded as a promising candidate for tumor immunotherapy. However, despite the encouraging results in animal models, only very modest antitumor effects have been confirmed in early clinical trials. Recently, several clinical studies have been initiated in which IL-12 was applied as an adjuvant in cancer vaccines, in gene therapy including locoregional injections of IL-12 plasmid, and in the form of tumor-targeting immunocytokines (IL-12 fused to monoclonal antibodies)
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Biomedical and Life Sciences (Springer-11642)
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