國立虎尾科技大學 |

GABAB receptor

Record Type:	Language materials, printed : Monograph/item
Title/Author:	GABAB receptor/ edited by Giancarlo Colombo.
other author:	Colombo, Giancarlo.
Published:	Cham :Springer International Publishing : : 2016.,
Description:	xx, 385 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	GABA - Receptors. -
Online resource:	http://dx.doi.org/10.1007/978-3-319-46044-4
ISBN:	9783319460444

GABAB receptor
GABAB receptor[electronic resource] /edited by Giancarlo Colombo. - Cham :Springer International Publishing :2016. - xx, 385 p. :ill., digital ;24 cm. - The receptors ;v.29. - Receptors ;v.28..

1. Historical Perspectives on the GABAB Receptor -- Section 1. Chemistry -- 2. Chemistry of GABAB Receptor Ligands: Focus on Agonists and Antagonists -- 3. Chemistry of GABAB Receptor Ligands: Focus on Positive Allosteric Modulators -- Section 2. Molecular Biology, Biochemistry, & Physiology -- 4. Molecular Structure and Trafficking of the GABAB Receptor -- 5. Distribution and Localization of the GABAB Receptor -- 6. Activation Mechanism and Allosteric Properties of the GABAB Receptor -- 7. Modulation of Neurotransmission by the GABAB Receptor -- 8. GABAB Receptor Functions In The Mesolimbic Dopamine System -- Section 3. Pharmacology -- 9. Drug Discrimination Studies for Investigations on the Mechanisms of Action of GABAB Receptor Ligands -- 10. Targeting the GABAB Receptor for the Treatment of Epilepsy -- 11. Targeting the GABAB Receptor for the Treatment of Pain -- 12. Targeting the GABAB Receptor for the Treatment of Psychiatric Disorders -- 13. Targeting the GABAB Receptor for the Treatment of Fragile X Syndrome and Autism Spectrum Disorders -- 14. Targeting the GABAB Receptor for the Treatment of Substance Use Disorder -- 15. Targeting the GABAB Receptor for the Treatment of Alcohol Use Disorder -- 16. Targeting GABAB Receptors for the Treatment of Gastroesophageal Reflux Disease and Chronic Cough -- 17. Baclofen: Therapeutic Use and Potential of the Prototypic GABAB Receptor Agonist -- 18. Allosteric Modulators: The New Generation of GABAB Receptor Ligands -- 19. GABAB Receptor Antagonists as Cognition Enhancers.

An up-to-date comprehensive overview of the GABAB receptor system with a particular focus on the most recent therapeutic applications and potential. This receptor system has recently been implicated in several diseases and disorders including gastroesophageal reflux disease, epilepsy, mood disorders, depression, and alcohol and substance use disorder. The authors, leading researchers in the field, explore a number of approaches, including medicinal chemistry, molecular biology, physiology, and preclinical and clinical pharmacology. This overview provides a translational perspective on the potential of the GABA B receptor pharmacology.

ISBN: 9783319460444

Standard No.: 10.1007/978-3-319-46044-4doiSubjects--Topical Terms:

581761
GABA
--Receptors.

LC Class. No.: QP563.G32

Dewey Class. No.: 572.696

GABAB receptor
LDR:03135nam a2200325 a 4500 001 868502
003 DE-He213
005 20161219154554.0
006 m d
007 cr nn 008maaau
008 170720s2016 gw s 0 eng d
020 $a 9783319460444 $q (electronic bk.)
020 $a 9783319460420 $q (paper)
024 7 $a 10.1007/978-3-319-46044-4 $2 doi
035 $a 978-3-319-46044-4
040 $a GP $c GP
041 0 $a eng
050 4 $a QP563.G32
072 7 $a PSAN $2 bicssc
072 7 $a MED057000 $2 bisacsh
082 0 4 $a 572.696 $2 23
090 $a QP563.G32 $b G112 2016
245 0 0 $a GABAB receptor $h [electronic resource] / $c edited by Giancarlo Colombo.
260 $a Cham : $c 2016. $b Springer International Publishing : $b Imprint: Humana Press,
300 $a xx, 385 p. : $b ill., digital ; $c 24 cm.
490 1 $a The receptors ; $v v.29
505 0 $a 1. Historical Perspectives on the GABAB Receptor -- Section 1. Chemistry -- 2. Chemistry of GABAB Receptor Ligands: Focus on Agonists and Antagonists -- 3. Chemistry of GABAB Receptor Ligands: Focus on Positive Allosteric Modulators -- Section 2. Molecular Biology, Biochemistry, & Physiology -- 4. Molecular Structure and Trafficking of the GABAB Receptor -- 5. Distribution and Localization of the GABAB Receptor -- 6. Activation Mechanism and Allosteric Properties of the GABAB Receptor -- 7. Modulation of Neurotransmission by the GABAB Receptor -- 8. GABAB Receptor Functions In The Mesolimbic Dopamine System -- Section 3. Pharmacology -- 9. Drug Discrimination Studies for Investigations on the Mechanisms of Action of GABAB Receptor Ligands -- 10. Targeting the GABAB Receptor for the Treatment of Epilepsy -- 11. Targeting the GABAB Receptor for the Treatment of Pain -- 12. Targeting the GABAB Receptor for the Treatment of Psychiatric Disorders -- 13. Targeting the GABAB Receptor for the Treatment of Fragile X Syndrome and Autism Spectrum Disorders -- 14. Targeting the GABAB Receptor for the Treatment of Substance Use Disorder -- 15. Targeting the GABAB Receptor for the Treatment of Alcohol Use Disorder -- 16. Targeting GABAB Receptors for the Treatment of Gastroesophageal Reflux Disease and Chronic Cough -- 17. Baclofen: Therapeutic Use and Potential of the Prototypic GABAB Receptor Agonist -- 18. Allosteric Modulators: The New Generation of GABAB Receptor Ligands -- 19. GABAB Receptor Antagonists as Cognition Enhancers.
520 $a An up-to-date comprehensive overview of the GABAB receptor system with a particular focus on the most recent therapeutic applications and potential. This receptor system has recently been implicated in several diseases and disorders including gastroesophageal reflux disease, epilepsy, mood disorders, depression, and alcohol and substance use disorder. The authors, leading researchers in the field, explore a number of approaches, including medicinal chemistry, molecular biology, physiology, and preclinical and clinical pharmacology. This overview provides a translational perspective on the potential of the GABA B receptor pharmacology.
650 0 $a GABA $x Receptors. $3 581761
650 1 4 $a Biomedicine. $3 593880
650 2 4 $a Neurosciences. $3 593561
650 2 4 $a Neurology. $3 593894
700 1 $a Colombo, Giancarlo. $3 1116164
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer eBooks
830 0 $a Receptors ; $v v.28. $3 1115237
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-46044-4
950 $a Biomedical and Life Sciences (Springer-11642)