國立虎尾科技大學 |

Sequential Monte Carlo methods : = applications to disease surveillance and fMRI data.

Record Type:	Language materials, manuscript : Monograph/item
Title/Author:	Sequential Monte Carlo methods :/
Reminder of title:	applications to disease surveillance and fMRI data.
Author:	Sheinson, Daniel M.
Description:	1 online resource (217 pages)
Notes:	Source: Dissertation Abstracts International, Volume: 76-03(E), Section: B.
Subject:	Statistics. -
Online resource:	click for full text (PQDT)
ISBN:	9781321350135

Sequential Monte Carlo methods : = applications to disease surveillance and fMRI data.
Sheinson, Daniel M.

Sequential Monte Carlo methods :applications to disease surveillance and fMRI data. - 1 online resource (217 pages)

Source: Dissertation Abstracts International, Volume: 76-03(E), Section: B.

Thesis (Ph.D.)--University of California, Santa Barbara, 2014.

Includes bibliographical references

We present contributions to epidemic tracking and analysis of fMRI data using sequential Monte Carlo methods within a state-space modeling framework. Using a model for tracking and prediction of a disease outbreak via a syndromic surveillance system, we compare the performance of several particle filtering algorithms in terms of their abilities to efficiently estimate disease states and unknown fixed parameters governing disease transmission. In this context, we demonstrate that basic particle filters may fail due to degeneracy when estimating fixed parameters, and we suggest the use of an algorithm developed by Liu and West (2001), which incorporates a kernel density approximation to the filtered distribution of the fixed parameters to allow for their regeneration. In addition, we show that seemingly uninformative uniform priors on fixed parameters can affect posterior inferences, and we suggest the use of priors bounded only by the support of the parameter. We demonstrate the negative impact of using multinomial resampling and suggest the use of either stratified or residual resampling within the particle filter. We also run a particle MCMC algorithm and show that the performance of the Liu and West (2001) particle filter is competitive with particle MCMC in this particular syndromic surveillance model setting. Finally, the improved performance of the Liu and West (2001) particle filter enables us to relax prior assumptions on model parameters, yet still provide reasonable estimates for model parameters and disease states.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2018

Mode of access: World Wide Web

ISBN: 9781321350135Subjects--Topical Terms:

556824
Statistics.
Index Terms--Genre/Form:

554714
Electronic books.

Sequential Monte Carlo methods : = applications to disease surveillance and fMRI data.
LDR:04092ntm a2200349K 4500 001 913753
005 20180622095236.5
006 m o u
007 cr mn||||a|a||
008 190606s2014 xx obm 000 0 eng d
020 $a 9781321350135
035 $a (MiAaPQ)AAI3645699
035 $a (MiAaPQ)ucsb:12274
035 $a AAI3645699
040 $a MiAaPQ $b eng $c MiAaPQ
100 1 $a Sheinson, Daniel M. $3 1186716
245 1 0 $a Sequential Monte Carlo methods : $b applications to disease surveillance and fMRI data.
264 0 $c 2014
300 $a 1 online resource (217 pages)
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
500 $a Source: Dissertation Abstracts International, Volume: 76-03(E), Section: B.
500 $a Advisers: Jarad Niemi; Wendy Meiring.
502 $a Thesis (Ph.D.)--University of California, Santa Barbara, 2014.
504 $a Includes bibliographical references
520 $a We present contributions to epidemic tracking and analysis of fMRI data using sequential Monte Carlo methods within a state-space modeling framework. Using a model for tracking and prediction of a disease outbreak via a syndromic surveillance system, we compare the performance of several particle filtering algorithms in terms of their abilities to efficiently estimate disease states and unknown fixed parameters governing disease transmission. In this context, we demonstrate that basic particle filters may fail due to degeneracy when estimating fixed parameters, and we suggest the use of an algorithm developed by Liu and West (2001), which incorporates a kernel density approximation to the filtered distribution of the fixed parameters to allow for their regeneration. In addition, we show that seemingly uninformative uniform priors on fixed parameters can affect posterior inferences, and we suggest the use of priors bounded only by the support of the parameter. We demonstrate the negative impact of using multinomial resampling and suggest the use of either stratified or residual resampling within the particle filter. We also run a particle MCMC algorithm and show that the performance of the Liu and West (2001) particle filter is competitive with particle MCMC in this particular syndromic surveillance model setting. Finally, the improved performance of the Liu and West (2001) particle filter enables us to relax prior assumptions on model parameters, yet still provide reasonable estimates for model parameters and disease states.
520 $a We also analyze real and simulated fMRI data using a state-space formulation of a regression model with autocorrelated error structure. We demonstrate via simulation that analyzing autocorrelated fMRI data using a model with independent error structure can inflate the false positive rate of concluding significant neural activity, and we compare methods of accounting for autocorrelation in fMRI data by examining ROC curves. In addition, we show that comparing models with different autocorrelated error structures on the basis of the independence of fitted model residuals can produce misleading results. Using data collected from an fMRI experiment featuring an episodic word recognition task, we estimate parameters in dynamic regression models using maximum likelihood and identify clusters of low and high activation in specific brain regions. We compare alternative models for fMRI time series from these brain regions by approximating the marginal likelihood of the data using particle learning. Our results suggest that a regression model with a dynamic intercept is the preferred model for most fMRI time series in the episodic word recognition experiment within the brain regions we considered, while a model with a dynamic slope is preferred for a small percentage of voxels in these brain regions.
533 $a Electronic reproduction. $b Ann Arbor, Mich. : $c ProQuest, $d 2018
538 $a Mode of access: World Wide Web
650 4 $a Statistics. $3 556824
650 4 $a Epidemiology. $3 635923
650 4 $a Neurosciences. $3 593561
655 7 $a Electronic books. $2 local $3 554714
690 $a 0463
690 $a 0766
690 $a 0317
710 2 $a ProQuest Information and Learning Co. $3 1178819
710 2 $a University of California, Santa Barbara. $b Statistics and Applied Probability. $3 1186717
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3645699 $z click for full text (PQDT)