國立虎尾科技大學 |

Genomic selection with deep neural networks.

Record Type:	Language materials, manuscript : Monograph/item
Title/Author:	Genomic selection with deep neural networks./
Author:	McDowell, Riley.
Description:	1 online resource (49 pages)
Notes:	Source: Masters Abstracts International, Volume: 56-03.
Subject:	Plant sciences. -
Online resource:	click for full text (PQDT)
ISBN:	9781369528244

Genomic selection with deep neural networks.
McDowell, Riley.

Genomic selection with deep neural networks. - 1 online resource (49 pages)

Source: Masters Abstracts International, Volume: 56-03.

Thesis (M.S.)--Iowa State University, 2016.

Includes bibliographical references

Reduced costs for DNA marker technology has generated a huge amount of molecular data and made it economically feasible to generate dense genome-wide marker maps of lines in a breeding program. Increased data density and volume has driven an exploration of tools and techniques to analyze these data for cultivar improvement. Data science theory and application has experienced a resurgence of research into techniques to detect or "learn" patterns in noisy data in a variety of technical applications. Several variants of machine learning have been proposed for analyzing large DNA marker data sets to aid in phenotype prediction and genomic selection. Here, we present a review of the genomic prediction and machine learning literature. We apply deep learning techniques from machine learning research to six phenotypic prediction tasks using published reference datasets. Because regularization frequently improves neural network prediction accuracy, we included regularization methods in the neural network models. The neural network models are compared to a selection of regularized Bayesian and linear regression techniques commonly employed for phenotypic prediction and genomic selection. On three of the phenotype prediction tasks, regularized neural networks were the most accurate of the models evaluated. Surprisingly, for these data sets the depth of the network architecture did not affect the accuracy of the trained model. We also find that concerns about the computer processing time needed to train neural network models to perform well in genomic prediction tasks may not apply when Graphics Processing Units are used for model training.

Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2018

Mode of access: World Wide Web

ISBN: 9781369528244Subjects--Topical Terms:

1179743
Plant sciences.
Index Terms--Genre/Form:

554714
Electronic books.

Genomic selection with deep neural networks.
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245 1 0 $a Genomic selection with deep neural networks.
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500 $a Source: Masters Abstracts International, Volume: 56-03.
500 $a Includes supplementary digital materials.
500 $a Advisers: David Grant; William Beavis.
502 $a Thesis (M.S.)--Iowa State University, 2016.
504 $a Includes bibliographical references
520 $a Reduced costs for DNA marker technology has generated a huge amount of molecular data and made it economically feasible to generate dense genome-wide marker maps of lines in a breeding program. Increased data density and volume has driven an exploration of tools and techniques to analyze these data for cultivar improvement. Data science theory and application has experienced a resurgence of research into techniques to detect or "learn" patterns in noisy data in a variety of technical applications. Several variants of machine learning have been proposed for analyzing large DNA marker data sets to aid in phenotype prediction and genomic selection. Here, we present a review of the genomic prediction and machine learning literature. We apply deep learning techniques from machine learning research to six phenotypic prediction tasks using published reference datasets. Because regularization frequently improves neural network prediction accuracy, we included regularization methods in the neural network models. The neural network models are compared to a selection of regularized Bayesian and linear regression techniques commonly employed for phenotypic prediction and genomic selection. On three of the phenotype prediction tasks, regularized neural networks were the most accurate of the models evaluated. Surprisingly, for these data sets the depth of the network architecture did not affect the accuracy of the trained model. We also find that concerns about the computer processing time needed to train neural network models to perform well in genomic prediction tasks may not apply when Graphics Processing Units are used for model training.
533 $a Electronic reproduction. $b Ann Arbor, Mich. : $c ProQuest, $d 2018
538 $a Mode of access: World Wide Web
650 4 $a Plant sciences. $3 1179743
650 4 $a Computer science. $3 573171
655 7 $a Electronic books. $2 local $3 554714
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710 2 $a Iowa State University. $b Agronomy. $3 1148552
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