國立虎尾科技大學 |

Novel optical endoscopes for early cancer diagnosis and therapy

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Novel optical endoscopes for early cancer diagnosis and therapy/ by Dale Jonathan Waterhouse.
Author:	Waterhouse, Dale Jonathan.
Published:	Cham :Springer International Publishing : : 2019.,
Description:	xxi, 142 p. :ill. (some col.), digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	Endoscopy. -
Online resource:	https://doi.org/10.1007/978-3-030-21481-4
ISBN:	9783030214814

Novel optical endoscopes for early cancer diagnosis and therapy
Waterhouse, Dale Jonathan.

Novel optical endoscopes for early cancer diagnosis and therapy[electronic resource] /by Dale Jonathan Waterhouse. - Cham :Springer International Publishing :2019. - xxi, 142 p. :ill. (some col.), digital ;24 cm. - Springer theses,2190-5053. - Springer theses..

Translation of Optical Imaging Techniques -- Flexible Endoscopy: Early Detection of Dysplasia in Barrett's Oesophagus -- Flexible Endoscopy : Device Architecture -- Flexible Endoscopy: Optical Molecular Imaging -- Flexible Endoscopy: Multispectral Imaging -- Rigid Endoscopy for Intraoperative Imaging of Pituitary Adenoma -- Conclusions and Outlook -- Appendix.

This thesis describes the design, development, characterisation and clinical translation of three novel devices for optical endoscopic imaging. Over the past decade, rapid innovation in optics and photonics has led to the availability of low-cost and high-performance optical technologies that can be exploited for biomedical applications, but relatively few have been translated into clinic. The work presented outlines for the first time, a comprehensive analysis of the common barriers and unique challenges associated with the translation of optical imaging techniques. To assist developers streamline translation of optical imaging devices in future, a roadmap to clinical translation is outlined, and key translational characteristics are defined. Guided by these, subsequent development of endoscopic devices resulted in preparation and approval of endoscopes for first in human trials in the oesophagus, for early detection of cancer, and in the brain, for delineation of tumour during surgical resection. The thesis culminates in the presentation of results from the first in human use of a compact multispectral endoscope for imaging endogenous tissue contrast in the oesophagus. With continuation of the work as outlined at the end of this thesis, the novel techniques described have the potential to improve the standard of care in their respective indications.

ISBN: 9783030214814

Standard No.: 10.1007/978-3-030-21481-4doiSubjects--Topical Terms:

588795
Endoscopy.

LC Class. No.: RC78.7.E5 / W384 2019

Dewey Class. No.: 616.07545

Novel optical endoscopes for early cancer diagnosis and therapy
LDR:02812nam a2200349 a 4500 001 942107
003 DE-He213
005 20191213103556.0
006 m d
007 cr nn 008maaau
008 200417s2019 gw s 0 eng d
020 $a 9783030214814 $q (electronic bk.)
020 $a 9783030214807 $q (paper)
024 7 $a 10.1007/978-3-030-21481-4 $2 doi
035 $a 978-3-030-21481-4
040 $a GP $c GP
041 0 $a eng
050 4 $a RC78.7.E5 $b W384 2019
072 7 $a PHVD $2 bicssc
072 7 $a SCI058000 $2 bisacsh
072 7 $a MKSH $2 thema
072 7 $a PNRL $2 thema
082 0 4 $a 616.07545 $2 23
090 $a RC78.7.E5 $b W326 2019
100 1 $a Waterhouse, Dale Jonathan. $3 1229748
245 1 0 $a Novel optical endoscopes for early cancer diagnosis and therapy $h [electronic resource] / $c by Dale Jonathan Waterhouse.
260 $a Cham : $c 2019. $b Springer International Publishing : $b Imprint: Springer,
300 $a xxi, 142 p. : $b ill. (some col.), digital ; $c 24 cm.
490 1 $a Springer theses, $x 2190-5053
505 0 $a Translation of Optical Imaging Techniques -- Flexible Endoscopy: Early Detection of Dysplasia in Barrett's Oesophagus -- Flexible Endoscopy : Device Architecture -- Flexible Endoscopy: Optical Molecular Imaging -- Flexible Endoscopy: Multispectral Imaging -- Rigid Endoscopy for Intraoperative Imaging of Pituitary Adenoma -- Conclusions and Outlook -- Appendix.
520 $a This thesis describes the design, development, characterisation and clinical translation of three novel devices for optical endoscopic imaging. Over the past decade, rapid innovation in optics and photonics has led to the availability of low-cost and high-performance optical technologies that can be exploited for biomedical applications, but relatively few have been translated into clinic. The work presented outlines for the first time, a comprehensive analysis of the common barriers and unique challenges associated with the translation of optical imaging techniques. To assist developers streamline translation of optical imaging devices in future, a roadmap to clinical translation is outlined, and key translational characteristics are defined. Guided by these, subsequent development of endoscopic devices resulted in preparation and approval of endoscopes for first in human trials in the oesophagus, for early detection of cancer, and in the brain, for delineation of tumour during surgical resection. The thesis culminates in the presentation of results from the first in human use of a compact multispectral endoscope for imaging endogenous tissue contrast in the oesophagus. With continuation of the work as outlined at the end of this thesis, the novel techniques described have the potential to improve the standard of care in their respective indications.
650 0 $a Endoscopy. $3 588795
650 0 $a Cancer $x Diagnosis. $3 661324
650 1 4 $a Medical and Radiation Physics. $3 784894
650 2 4 $a Optics, Lasers, Photonics, Optical Devices. $3 1112289
650 2 4 $a Diagnostic Radiology. $3 593950
650 2 4 $a Cancer Research. $3 668358
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer eBooks
830 0 $a Springer theses. $3 831604
856 4 0 $u https://doi.org/10.1007/978-3-030-21481-4
950 $a Physics and Astronomy (Springer-11651)