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X-Ray Phase-Contrast Tomography = Underlying Physics and Developments for Breast Imaging /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	X-Ray Phase-Contrast Tomography/ by Luca Brombal.
Reminder of title:	Underlying Physics and Developments for Breast Imaging /
Author:	Brombal, Luca.
Description:	XIII, 140 p. 68 illus., 53 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Biophysics. -
Online resource:	https://doi.org/10.1007/978-3-030-60433-2
ISBN:	9783030604332

X-Ray Phase-Contrast Tomography = Underlying Physics and Developments for Breast Imaging /
Brombal, Luca.

X-Ray Phase-Contrast TomographyUnderlying Physics and Developments for Breast Imaging /[electronic resource] :by Luca Brombal. - 1st ed. 2020. - XIII, 140 p. 68 illus., 53 illus. in color.online resource. - Springer Theses, Recognizing Outstanding Ph.D. Research,2190-5053. - Springer Theses, Recognizing Outstanding Ph.D. Research,.

Introduction -- Physics of Propagation-based X-ray Tomography -- Propagation-based Breast CT and SYRMA-3D Project -- Detector and Pre-processing -- Experimental Optimization of Propagation-based BCT -- Three-Dimensional Imaging: A Clinically Oriented Focus -- Do We Need Clinical Applications in Synchrotrons? -- Conclusions.

X-ray imaging is a corner stone of breast cancer diagnosis. By exploiting the phase shift of X-rays rather than their attenuation, phase-contrast tomography has the potential to dramatically increase the visibility of small and low contrast features, thus leading to better diagnosis. This thesis presents research on the first synchrotron-based project developing a clinical phase-contrast breast computed tomography (CT) setup at Elettra, the Italian Syncrotron Radiation Facility. This book includes a comprehensive theoretical background on propagation-based phase-contrast imaging, exploring and extending the most recent image formation models. Along with theory, many practical implementation and optimization issues, ranging from detector-specific processing to setup geometry, are tackled on the basis of a large number of experimental evidences. Most of the modelling results and data analysis have general validity, being a valuable framework for optimization of phase-contrast setups. Results obtained at synchrotron are also compared with "real world" laboratory sources: both a first-of-its-kind comparison with one of the few hospital breast CT systems and a state-of-the-art implementation of monochromatic phase-contrast micro-tomography with a conventional rotating anode source are presented. On a more general level, this work sheds a light on the importance of synchrotron-based clinical programs, which are key to trigger the long-anticipated transition of phase-contrast imaging from synchrotrons to hospitals. .

ISBN: 9783030604332

Standard No.: 10.1007/978-3-030-60433-2doiSubjects--Topical Terms:

581576
Biophysics.

LC Class. No.: QH505

Dewey Class. No.: 571.4

X-Ray Phase-Contrast Tomography = Underlying Physics and Developments for Breast Imaging /
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