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Handbook of traumatic brain injury and neurodegeneration

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Handbook of traumatic brain injury and neurodegeneration/ Rudy J. Castellani.
other author:	Castellani, Rudy J.
Published:	Washington :IOS Press, : 2020.,
Description:	1 online resource (xiii, 490 p.)
Subject:	Brain - Wounds and injuries. -
Online resource:	http://ebooks.windeal.com.tw/ios/cover.asp?isbn=9781643680644
ISBN:	9781643680651 (ebk.)

Handbook of traumatic brain injury and neurodegeneration
Handbook of traumatic brain injury and neurodegeneration[electronic resource] /Rudy J. Castellani. - Washington :IOS Press,2020. - 1 online resource (xiii, 490 p.) - Advances in alzheimer's disease ;volume 7. - Advances in Alzheimer's disease (Series) ;v. 3..

ncludes bibliographical references and indexes.

"Holbourne's theory that rotational head movement and shear strains were limiting factors in producing acute parenchymal brain damage was a watershed moment in understanding traumatic brain injury (TBI). Long term effects, and in particular neurodegenerative proteinopathy subsequent to TBI, remain theoretical, notwithstanding the poorly understood 'punch drunk' syndrome of the early and mid-20th century, and the 21st century concept of chronic traumatic encephalopathy. This book, the Handbook of Traumatic Brain Injury and Neurodegeneration, has as its theme the marriage between neurodegenerative disease and neurotrauma through TBI surrogates such as sport, military service, and experimental models, and the legitimacy of that marriage. In the 32 contributions included here, this handbook not only explores the deleterious effects of genuine TBI, but also, and more importantly, the relationship between TBI and neurodegeneration. Controversy notwithstanding, there is much to be learned about the biological effects of TBI, substrates for long-term sequelae, the relationship between TBI and diverse neuropsychiatric disorders, and targets for therapy. The overall message to the neuroscience community from these papers may be a cautionary tale. The null hypothesis, that there is no causal relationship between TBI and progressive neurodegenerative disease, appears to be very much in play, and the book will be of interest to all those working in the field"--

ISBN: 9781643680651 (ebk.)

LCCN: 2020936247Subjects--Topical Terms:

768574
Brain
--Wounds and injuries.

LC Class. No.: RD594 / .H36 2020

Dewey Class. No.: 617.4/81044

Handbook of traumatic brain injury and neurodegeneration
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020 $a 9781643680644 (hbk.)
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050 0 0 $a RD594 $b .H36 2020
082 0 0 $a 617.4/81044 $2 23
245 0 0 $a Handbook of traumatic brain injury and neurodegeneration $h [electronic resource] / $c Rudy J. Castellani.
260 $a Washington : $b IOS Press, $c 2020.
300 $a 1 online resource (xiii, 490 p.)
490 0 $a Advances in alzheimer's disease ; $v volume 7
504 $a ncludes bibliographical references and indexes.
520 $a "Holbourne's theory that rotational head movement and shear strains were limiting factors in producing acute parenchymal brain damage was a watershed moment in understanding traumatic brain injury (TBI). Long term effects, and in particular neurodegenerative proteinopathy subsequent to TBI, remain theoretical, notwithstanding the poorly understood 'punch drunk' syndrome of the early and mid-20th century, and the 21st century concept of chronic traumatic encephalopathy. This book, the Handbook of Traumatic Brain Injury and Neurodegeneration, has as its theme the marriage between neurodegenerative disease and neurotrauma through TBI surrogates such as sport, military service, and experimental models, and the legitimacy of that marriage. In the 32 contributions included here, this handbook not only explores the deleterious effects of genuine TBI, but also, and more importantly, the relationship between TBI and neurodegeneration. Controversy notwithstanding, there is much to be learned about the biological effects of TBI, substrates for long-term sequelae, the relationship between TBI and diverse neuropsychiatric disorders, and targets for therapy. The overall message to the neuroscience community from these papers may be a cautionary tale. The null hypothesis, that there is no causal relationship between TBI and progressive neurodegenerative disease, appears to be very much in play, and the book will be of interest to all those working in the field"-- $c Provided by publisher.
650 0 $a Brain $x Wounds and injuries. $3 768574
650 0 $a Nervous system $x Degeneration. $3 668516
700 1 $a Castellani, Rudy J. $3 1340967
830 0 $a Advances in Alzheimer's disease (Series) ; $v v. 3. $3 1057534
856 4 0 $u http://ebooks.windeal.com.tw/ios/cover.asp?isbn=9781643680644