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Neurobiology of addiction

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Neurobiology of addiction/ George F. Koob, Michel Le Moal.
Author:	Koob, George F.
other author:	Le Moal, Michel.
Published:	London :Elsevier Academic, : c2006.,
Description:	1 online resource (viii, 490 p.) :ill. (some col.) :
Subject:	Drug addiction. -
Online resource:	http://www.sciencedirect.com/science/book/9780124192393
ISBN:	9780124192393

Neurobiology of addiction
Koob, George F.

Neurobiology of addiction[electronic resource] /George F. Koob, Michel Le Moal. - London :Elsevier Academic,c2006. - 1 online resource (viii, 490 p.) :ill. (some col.)

Includes bibliographical references and index.

What is addiction? -- Animal models of drug addiction -- Psychostimulants -- Opioids -- Alcohol -- Nicotine -- Cannabinoids -- Imaging -- Neurobiological theories of addiction -- Drug addiction : transition from neuroadaptation to pathophysiology.

Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neurobiological mechanism of action for each drug class at the molecular, cellular and neurocircuitry level of analysis. A chapter on neuroimaging and drug addiction provides a synthesis of exciting new data from neuroimaging in human addicts a unique perspective unavailable from animal studies. The final chapters explore theories of addiction at the neurobiological and neuroadaptational level both from a historical and integrative perspective. The book incorporates diverse finding with an emphasis on integration and synthesis rather than discrepancies or differences in the literature. Presents a unique perspective on addiction that emphasizes molecular, cellular and neurocircuitry changes in the transition to addiction Synthesizes diverse findings on the neurobiology of addiction to provide a heuristic framework for future work Features extensive documentation through numerous original figures and tables that that will be useful for understanding and teaching.

ISBN: 9780124192393

Source: 102148:102166Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

654372
Drug addiction.
Index Terms--Genre/Form:

554714
Electronic books.

LC Class. No.: RC566 / .K66 2006eb

Dewey Class. No.: 616.86

National Library of Medicine Call No.: 2006 A-487

Neurobiology of addiction
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245 1 0 $a Neurobiology of addiction $h [electronic resource] / $c George F. Koob, Michel Le Moal.
260 $a London : $b Elsevier Academic, $c c2006.
300 $a 1 online resource (viii, 490 p.) : $b ill. (some col.)
504 $a Includes bibliographical references and index.
505 0 $a What is addiction? -- Animal models of drug addiction -- Psychostimulants -- Opioids -- Alcohol -- Nicotine -- Cannabinoids -- Imaging -- Neurobiological theories of addiction -- Drug addiction : transition from neuroadaptation to pathophysiology.
505 0 $a Preface -- Acknowledgments -- 1. What is addiction -- 2. Animal models of drug addiction -- 3 Psychostimulants -- 4. Opioids -- 5. Alcohol -- 6. Nicotine -- 7. Cannabinoids -- 8. Imaging -- 9. Neurobiological theories of addiction -- 10. Drug addiction: transition from neuroadaptation to pathophysiology -- Appendix 1. Psychostimulants -- Appendix 2. Opioids -- Appendix 3. Alcohol -- Appendix 4. Nicotine -- Appendix 5. Cannabinoids -- Index.
520 $a Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neurobiological mechanism of action for each drug class at the molecular, cellular and neurocircuitry level of analysis. A chapter on neuroimaging and drug addiction provides a synthesis of exciting new data from neuroimaging in human addicts a unique perspective unavailable from animal studies. The final chapters explore theories of addiction at the neurobiological and neuroadaptational level both from a historical and integrative perspective. The book incorporates diverse finding with an emphasis on integration and synthesis rather than discrepancies or differences in the literature. Presents a unique perspective on addiction that emphasizes molecular, cellular and neurocircuitry changes in the transition to addiction Synthesizes diverse findings on the neurobiology of addiction to provide a heuristic framework for future work Features extensive documentation through numerous original figures and tables that that will be useful for understanding and teaching.
588 $a Description based on print version record.
650 0 $a Drug addiction. $3 654372
650 0 $a Neurobiology. $3 573189
650 0 $a Neuropharmacology. $3 677629
650 1 2 $a Substance-Related Disorders $x physiopathology. $3 581876
650 2 2 $a Behavior, Addictive $x physiopathology. $3 862586
655 4 $a Electronic books. $2 local $3 554714
700 1 $a Le Moal, Michel. $3 862585
856 4 0 $3 ScienceDirect $u http://www.sciencedirect.com/science/book/9780124192393