國立虎尾科技大學 |

Complement Activation in Malaria Immunity and Pathogenesis

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Complement Activation in Malaria Immunity and Pathogenesis/ edited by José A. Stoute.
other author:	Stoute, José A.
Description:	XII, 149 p. 22 illus., 17 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Immunology. -
Online resource:	https://doi.org/10.1007/978-3-319-77258-5
ISBN:	9783319772585

Complement Activation in Malaria Immunity and Pathogenesis
Complement Activation in Malaria Immunity and Pathogenesis[electronic resource] /edited by José A. Stoute. - 1st ed. 2018. - XII, 149 p. 22 illus., 17 illus. in color.online resource.

The Complement System -- Mechanisms of Complement Activation in Malaria -- Role of Complement in Severe Malarial Anemia -- Role of Complement in Cerebral Malaria -- Role of Complement in Placental Malaria -- Complement Evasion Mechanisms of the Human Pathogen Plasmodium falciparum -- Role of Complement in Immunity Against Malaria -- Complement-like System in the Mosquito Responses Against Malaria Parasites.

Plasmodium falciparum malaria is responsible for the deaths of nearly 500,000 people each year. Much attention has been paid to antibody and cellular mechanisms of immunity against this pathogen. By contrast, the role that the complement system plays in immunity and pathogenesis in this infection is not very well recognized or understood. Based on the work of a number of research groups, we know that complement plays an important role in these processes. In this book, some of the leading scientists in the field discuss the mechanisms of complement activation during malaria infection as well as the role of complement in the pathogenesis of key syndromes such as severe malarial anemia, cerebral malaria, and placental malaria. In addition, they review recently-identified complement evasion strategies of P. falciparum merozoites, and how these mechanisms may translate into paradoxical enhancement of infection rather than protection. Finally, they also discuss the role of the mosquito complement system on immunity against the parasite. .

ISBN: 9783319772585

Standard No.: 10.1007/978-3-319-77258-5doiSubjects--Topical Terms:

592892
Immunology.

LC Class. No.: QR180-189.5

Dewey Class. No.: 616.079

Complement Activation in Malaria Immunity and Pathogenesis
LDR:02841nam a22003975i 4500 001 997492
003 DE-He213
005 20200630221850.0
007 cr nn 008mamaa
008 201225s2018 gw | s |||| 0|eng d
020 $a 9783319772585 $9 978-3-319-77258-5
024 7 $a 10.1007/978-3-319-77258-5 $2 doi
035 $a 978-3-319-77258-5
050 4 $a QR180-189.5
072 7 $a MJCM $2 bicssc
072 7 $a MED044000 $2 bisacsh
072 7 $a MJCM $2 thema
082 0 4 $a 616.079 $2 23
245 1 0 $a Complement Activation in Malaria Immunity and Pathogenesis $h [electronic resource] / $c edited by José A. Stoute.
250 $a 1st ed. 2018.
264 1 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2018.
300 $a XII, 149 p. 22 illus., 17 illus. in color. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
505 0 $a The Complement System -- Mechanisms of Complement Activation in Malaria -- Role of Complement in Severe Malarial Anemia -- Role of Complement in Cerebral Malaria -- Role of Complement in Placental Malaria -- Complement Evasion Mechanisms of the Human Pathogen Plasmodium falciparum -- Role of Complement in Immunity Against Malaria -- Complement-like System in the Mosquito Responses Against Malaria Parasites.
520 $a Plasmodium falciparum malaria is responsible for the deaths of nearly 500,000 people each year. Much attention has been paid to antibody and cellular mechanisms of immunity against this pathogen. By contrast, the role that the complement system plays in immunity and pathogenesis in this infection is not very well recognized or understood. Based on the work of a number of research groups, we know that complement plays an important role in these processes. In this book, some of the leading scientists in the field discuss the mechanisms of complement activation during malaria infection as well as the role of complement in the pathogenesis of key syndromes such as severe malarial anemia, cerebral malaria, and placental malaria. In addition, they review recently-identified complement evasion strategies of P. falciparum merozoites, and how these mechanisms may translate into paradoxical enhancement of infection rather than protection. Finally, they also discuss the role of the mosquito complement system on immunity against the parasite. .
650 0 $a Immunology. $3 592892
650 0 $a Parasitology. $3 669054
650 0 $a Infectious diseases. $3 1102043
650 0 $a Tropical medicine. $3 673736
650 0 $a Laboratory medicine. $3 1254567
650 2 4 $a Infectious Diseases. $3 668393
650 2 4 $a Tropical Medicine. $3 668883
650 2 4 $a Laboratory Medicine. $3 673604
700 1 $a Stoute, José A. $e editor. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1288870
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9783319772578
776 0 8 $i Printed edition: $z 9783319772592
776 0 8 $i Printed edition: $z 9783030084127
856 4 0 $u https://doi.org/10.1007/978-3-319-77258-5
912 $a ZDB-2-SBL
912 $a ZDB-2-SXB
950 $a Biomedical and Life Sciences (SpringerNature-11642)
950 $a Biomedical and Life Sciences (R0) (SpringerNature-43708)