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Reproductomics = the --omics revolution and its impact on human reproductive medicine /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Reproductomics/ José A. Horcajadas, Jaime Gosálvez.
其他題名:	the --omics revolution and its impact on human reproductive medicine /
作者:	Horcajadas, José A.,
其他作者:	Gosálvez, Jaime,
出版者:	London, United Kingdom :Academic Press, an imprint of Elsevier, : 2018.,
面頁冊數:	1 online resource.
標題:	Human reproduction. -
電子資源:	https://www.sciencedirect.com/science/book/9780128125717
ISBN:	9780128126769 (electronic bk.)

Reproductomics = the --omics revolution and its impact on human reproductive medicine /
Horcajadas, José A.,

Reproductomicsthe --omics revolution and its impact on human reproductive medicine /[electronic resource] :José A. Horcajadas, Jaime Gosálvez. - London, United Kingdom :Academic Press, an imprint of Elsevier,2018. - 1 online resource.

Front Cover; Reproductomics: The -Omics Revolution and Its Impact on Human Reproductive Medicine; Copyright; Contents; Contributors; Preface; Introduction: Human Genome Projects: The Omics Starting Point; Preomics Era; Omics Era; Omics in the Assisted Reproduction Era; Genomics; Prenatal; Transcriptomics; Proteomics and Metabolomics; References; Chapter 1: Is the Classic Spermiogram Still Informative? How Did It Develop and Where Is It Going?; Introduction; Specific Aspects of Basic Semen Analysis; Semen Volume; Estimation of Sperm Concentration; Sperm Motility

Recent advances in genomic and omics analysis have triggered a revolution affecting nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, and infertility treatment. Reproductomics: The -Omics Revolution and Its Impact on Human Reproductive Medicine demonstrates how various omics technologies are already aiding fertility specialists and clinicians in characterizing patients, counseling couples towards pregnancy success, informing embryo selection, and supporting many other positive outcomes. A diverse range of chapters from international experts examine the complex relationship between genomics, transcriptomics, proteomics, and metabolomics and their role in human reproduction, identifying molecular factors of clinical significance. With this book Editors Jaime Gosálvez and José A. Horcajadas have provided researchers and clinicians with a strong foundation for a new era of personalized reproductive medicine.

ISBN: 9780128126769 (electronic bk.)Subjects--Topical Terms:

782746
Human reproduction.
Index Terms--Genre/Form:

554714
Electronic books.

LC Class. No.: QP251.H46 / R47 2018eb

Dewey Class. No.: 612.6

Reproductomics = the --omics revolution and its impact on human reproductive medicine /
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505 0 $a Front Cover; Reproductomics: The -Omics Revolution and Its Impact on Human Reproductive Medicine; Copyright; Contents; Contributors; Preface; Introduction: Human Genome Projects: The Omics Starting Point; Preomics Era; Omics Era; Omics in the Assisted Reproduction Era; Genomics; Prenatal; Transcriptomics; Proteomics and Metabolomics; References; Chapter 1: Is the Classic Spermiogram Still Informative? How Did It Develop and Where Is It Going?; Introduction; Specific Aspects of Basic Semen Analysis; Semen Volume; Estimation of Sperm Concentration; Sperm Motility
505 8 $a The Biological Relevance of Sperm MotilitySperm Morphology Analysis; Plasma Membrane Integrity; Conclusions; References; Chapter 2: Genetic Variations and Male Infertility; Introduction; Single Nucleotide Polymorphisms; MTHFR Gene Polymorphisms; DAZL and DAZ Genes Polymorphisms; BRDT Gene Polymorphisms; TERT and TEP1 Genes; Cytochrome P4501A1; FSHR Gene Polymorphisms; ESR1 and ESR2 Gene Polymorphisms; PRM1 and PRM2 Genes Polymorphisms; Insertion Deletion Polymorphisms; POLG Gene Polymorphisms; AR Gene Polymorphisms; Copy Number Variations; Y Chromosome Microdeletions
505 8 $a Genome-Wide Association StudiesLimitations of Genetic Association Studies; Conclusion; References; Further Reading; Chapter 3: New Genetic Point Mutations in Male Infertility; Introduction; Genes and Male Factor Infertility; Male Sexual Differentiation Disorders and Gonadal Development Impairment; Spermatogenesis Alterations and Sperm Function Impairment; Single-Nucleotide Polymorphism; Final Comments; References; Chapter 4: Carrier Screening for Inherited Genetic Disorders: A Review of Current Practices; Introduction to Genetics; Genetic Disease and Inheritance
505 8 $a Introduction to Carrier ScreeningGuidelines for Carrier Screening; Carrier Screening Technologies; CBC and Hemoglobin Electrophoresis; HEXA (Tay-Sachs) Enzyme Analysis; Fragile X Syndrome-CGG and AGG Analysis; Spinal Muscular Atrophy (SMA) Dosage Analysis; Carrier Rates, Detection Rates, and Residual Risks; Reproductive Options for High-Risk Couples; Further Reading; Chapter 5: Telomeres in Germ Line and Early Embryo: An Overview; Historical Landmarks; Structure of Telomeres; Telomere Physiology; Telomeres in Aging and Age-Related Disease; Telomeres in Male Germ Line
505 8 $a Telomeres in Female Germ LineTelomeres in Early Embryo; Concluding Considerations; Acknowledgments; References; Chapter 6: Human Protamine Genes' Polymorphisms as a Possible Cause Underlying Male Infertility; Introduction; Protamine Structure and Functions; Protamine Genes Organization; PRM1/PRM2 Ratio; Protamine 1 Gene Polymorphisms; Polymorphisms in the Promoter Region; Polymorphisms in the Coding Region; Polymorphisms in the 32 Noncodifying Region; Protamine 2 Gene Polymorphisms; Polymorphisms in the Promoter Region; Polymorphisms in the Coding Region
520 $a Recent advances in genomic and omics analysis have triggered a revolution affecting nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, and infertility treatment. Reproductomics: The -Omics Revolution and Its Impact on Human Reproductive Medicine demonstrates how various omics technologies are already aiding fertility specialists and clinicians in characterizing patients, counseling couples towards pregnancy success, informing embryo selection, and supporting many other positive outcomes. A diverse range of chapters from international experts examine the complex relationship between genomics, transcriptomics, proteomics, and metabolomics and their role in human reproduction, identifying molecular factors of clinical significance. With this book Editors Jaime Gosálvez and José A. Horcajadas have provided researchers and clinicians with a strong foundation for a new era of personalized reproductive medicine.
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