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Introduction to protein mass spectrometry

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Introduction to protein mass spectrometry/ Pradip Kumar Ghosh.
Author:	Ghosh, Pradip K.,
Published:	London, UK :Academic Press is an imprint of Elsevier, : 2016.,
Description:	1 online resource.
Notes:	Includes index.
Subject:	Mass spectrometry. -
Online resource:	https://www.sciencedirect.com/science/book/9780128021026
ISBN:	9780128021125 (electronic bk.)

Introduction to protein mass spectrometry
Ghosh, Pradip K.,

Introduction to protein mass spectrometry[electronic resource] /Pradip Kumar Ghosh. - London, UK :Academic Press is an imprint of Elsevier,2016. - 1 online resource.

Includes index.

Title page; Table of Contents; Copyright page; Dedication; Preface; Chapter 1: Introduction; Chapter 2: Sample Preparation and Ionization for Mass Spectrometry; 2.1 Separation of protein mixtures; 2.2 Multidimensional separations; 2.3 Proteolysis; 2.4 Ionization of proteins and peptides; Chapter 3: Instruments; 3.1 Mass analysis; 3.2 Some examples of instruments; Chapter 4: Mass Spectrometry of Peptides and Proteins; 4.1 Proteins; 4.2 Alternative analysis methods; 4.3 Quantitation; 4.4 Peptide fragmentation: Experiments; 4.5 Data mining scheme for identifying peptide structural motifs.

Unlike many other methods which automatically yield an absolutely unique protein name as output, protein mass spectrometry generally requires a deduction of protein identity from determination of peptide fragmentation products. This book enables readers to both understand, and appreciate, how determinations about protein identity from mass spectrometric data are made.

ISBN: 9780128021125 (electronic bk.)Subjects--Topical Terms:

583253
Mass spectrometry.
Index Terms--Genre/Form:

554714
Electronic books.

LC Class. No.: QP519.9.M3

Dewey Class. No.: 543/.65

Introduction to protein mass spectrometry
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245 1 0 $a Introduction to protein mass spectrometry $h [electronic resource] / $c Pradip Kumar Ghosh.
260 $a London, UK : $b Academic Press is an imprint of Elsevier, $c 2016.
300 $a 1 online resource.
500 $a Includes index.
505 0 $a Title page; Table of Contents; Copyright page; Dedication; Preface; Chapter 1: Introduction; Chapter 2: Sample Preparation and Ionization for Mass Spectrometry; 2.1 Separation of protein mixtures; 2.2 Multidimensional separations; 2.3 Proteolysis; 2.4 Ionization of proteins and peptides; Chapter 3: Instruments; 3.1 Mass analysis; 3.2 Some examples of instruments; Chapter 4: Mass Spectrometry of Peptides and Proteins; 4.1 Proteins; 4.2 Alternative analysis methods; 4.3 Quantitation; 4.4 Peptide fragmentation: Experiments; 4.5 Data mining scheme for identifying peptide structural motifs.
505 8 $a 4.6 Peptide fragmentation: mechanism4.7 Possible pathways in the competition model; 4.8 Studying post translational modifications; 4.9 Chemical cross-linking/mass spectrometry; 4.10 Manual de novo sequencing of peptides; Chapter 5: Examples from Biological Applications; 5.1 Mapping intact protein isoforms using top-down proteomics; 5.2 Quantitative analysis of intact apolipoproteins in human HDL; 5.3 Rapid sequence analysis of some conotoxins -- combination of de novo, bottom-up methods; 5.4 Mass spectrometry of ribosomes; 5.5 Proteins in Purkinje cell post-synaptic densities.
505 8 $a 5.6 Neurexin-LRRTM2 interaction effect in synapse formation5.7 Rapid analysis of human plasma proteome -- an IMS-IMS-MS application; 5.8 Topology of two transient virus capsid assembly intermediates; 5.9 Mass spectrometry of intact V-type ATPases reveals bound lipids and the effects of nucleotide binding; 5.10 Mass spectrometric imaging of biological material; Chapter 6: Mass Spectrometry-Based Bioinformatics; 6.1 Peptides to proteins; 6.2 MS/MS fragments to peptides to proteins; 6.3 Data-dependent acquisition; 6.4 Targeted acquisition covering SRM and PRM; 6.5 Data-independent acquisition.
520 8 $a Unlike many other methods which automatically yield an absolutely unique protein name as output, protein mass spectrometry generally requires a deduction of protein identity from determination of peptide fragmentation products. This book enables readers to both understand, and appreciate, how determinations about protein identity from mass spectrometric data are made.
588 0 $a Online resource; title from PDF title page (ScienceDirect, viewed December 15, 2015).
650 0 $a Mass spectrometry. $3 583253
655 4 $a Electronic books. $2 local $3 554714
856 4 0 $u https://www.sciencedirect.com/science/book/9780128021026