國立虎尾科技大學 |

Exploring Pancreatic Metabolism and Malignancy

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Exploring Pancreatic Metabolism and Malignancy/ edited by Ganji Purnachandra Nagaraju, Aramati BM Reddy.
其他作者:	Nagaraju, Ganji Purnachandra.
面頁冊數:	XII, 268 p. 35 illus., 29 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Cancer research. -
電子資源:	https://doi.org/10.1007/978-981-32-9393-9
ISBN:	9789813293939

Exploring Pancreatic Metabolism and Malignancy
Exploring Pancreatic Metabolism and Malignancy[electronic resource] /edited by Ganji Purnachandra Nagaraju, Aramati BM Reddy. - 1st ed. 2019. - XII, 268 p. 35 illus., 29 illus. in color.online resource.

Chapter 1. Biology of pancreas and possible diseases -- Chapter 2. Pancreatitis: Clinical aspects of inflammatory phenotypes -- Chapter 3. Diabetes and Pancreatic Cancer – A Bidirectional Relationship Perspective -- Chapter 4. Metabolic Adaptations in Diabetes Mellitus and Cancer -- Chapter 5. Role of Mitochondria in pancreatic metabolism, diabetes and cancer -- Chapter 6. Targeting Mitochondrial Enzymes in Pancreatic Cancer -- Chapter 7. Diabetes with Pancreatic ductal adenocarcinoma -- Chapter 8. Role of Inflammatory Cytokines in the initiation and progression of Pancreatic Cancer -- Chapter 9. Perspectives and molecular understanding of pancreatic cancer stem cells -- Chapter 10. The Role of Hypoxia Inducible Factor-1α in Pancreatic Cancer and Diabetes Mellitus -- Chapter 11. Role of Heat shock protein 90 in Diabetes and Pancreatic Cancer Management -- Chapter 12. Insulin resistance is a common core tethered to diabetes and pancreatic cancer risk -- Chapter 13. Immunotherapy for Diabetogenic Pancreatitis and Pancreatic Cancer: An Update -- Chapter 14. Exosomes: Mediators and Therapeutic Targets of Diabetes and Pancreatic Cancer -- Chapter 15. Methods and models in exploring pancreatic functions.

This book comprehensively describes the association between metabolic syndrome and pancreatic cancer progression, and the mechanism of action and target definition with a view to drug discovery. Metabolic syndrome, which includes adnominal obesity, hypertension, dyslipidemia, and hyperglycemia, has recently been shown to play an important role in the etiology and progression of various cancers. Further, obesity and diabetes have been associated with an increased incidence of gastric cancers. The book reviews the key biological mechanisms underlying the association between metabolic dysregulation, including obesity-associated enhancement of growth factor signaling, inflammation, and perturbation in pancreatic cancer cell growth and metastasis. It also illustrates the role of the inflammatory signaling pathway in metabolic diseases as well as tumor growth and explores the potential of these pathways as the rational targets for pancreatic cancer therapy. Lastly, the book offers a comprehensive description of the challenges associated with diabetes and pancreatic cancer therapy.

ISBN: 9789813293939

Standard No.: 10.1007/978-981-32-9393-9doiSubjects--Topical Terms:

1253664
Cancer research.

LC Class. No.: RC261-271

Dewey Class. No.: 614.5999

Exploring Pancreatic Metabolism and Malignancy
LDR:03701nam a22003975i 4500 001 1005556
003 DE-He213
005 20200702010012.0
007 cr nn 008mamaa
008 210106s2019 si | s |||| 0|eng d
020 $a 9789813293939 $9 978-981-32-9393-9
024 7 $a 10.1007/978-981-32-9393-9 $2 doi
035 $a 978-981-32-9393-9
050 4 $a RC261-271
072 7 $a MJCL $2 bicssc
072 7 $a MED062000 $2 bisacsh
072 7 $a MJCL $2 thema
082 0 4 $a 614.5999 $2 23
245 1 0 $a Exploring Pancreatic Metabolism and Malignancy $h [electronic resource] / $c edited by Ganji Purnachandra Nagaraju, Aramati BM Reddy.
250 $a 1st ed. 2019.
264 1 $a Singapore : $b Springer Singapore : $b Imprint: Springer, $c 2019.
300 $a XII, 268 p. 35 illus., 29 illus. in color. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
505 0 $a Chapter 1. Biology of pancreas and possible diseases -- Chapter 2. Pancreatitis: Clinical aspects of inflammatory phenotypes -- Chapter 3. Diabetes and Pancreatic Cancer – A Bidirectional Relationship Perspective -- Chapter 4. Metabolic Adaptations in Diabetes Mellitus and Cancer -- Chapter 5. Role of Mitochondria in pancreatic metabolism, diabetes and cancer -- Chapter 6. Targeting Mitochondrial Enzymes in Pancreatic Cancer -- Chapter 7. Diabetes with Pancreatic ductal adenocarcinoma -- Chapter 8. Role of Inflammatory Cytokines in the initiation and progression of Pancreatic Cancer -- Chapter 9. Perspectives and molecular understanding of pancreatic cancer stem cells -- Chapter 10. The Role of Hypoxia Inducible Factor-1α in Pancreatic Cancer and Diabetes Mellitus -- Chapter 11. Role of Heat shock protein 90 in Diabetes and Pancreatic Cancer Management -- Chapter 12. Insulin resistance is a common core tethered to diabetes and pancreatic cancer risk -- Chapter 13. Immunotherapy for Diabetogenic Pancreatitis and Pancreatic Cancer: An Update -- Chapter 14. Exosomes: Mediators and Therapeutic Targets of Diabetes and Pancreatic Cancer -- Chapter 15. Methods and models in exploring pancreatic functions.
520 $a This book comprehensively describes the association between metabolic syndrome and pancreatic cancer progression, and the mechanism of action and target definition with a view to drug discovery. Metabolic syndrome, which includes adnominal obesity, hypertension, dyslipidemia, and hyperglycemia, has recently been shown to play an important role in the etiology and progression of various cancers. Further, obesity and diabetes have been associated with an increased incidence of gastric cancers. The book reviews the key biological mechanisms underlying the association between metabolic dysregulation, including obesity-associated enhancement of growth factor signaling, inflammation, and perturbation in pancreatic cancer cell growth and metastasis. It also illustrates the role of the inflammatory signaling pathway in metabolic diseases as well as tumor growth and explores the potential of these pathways as the rational targets for pancreatic cancer therapy. Lastly, the book offers a comprehensive description of the challenges associated with diabetes and pancreatic cancer therapy.
650 0 $a Cancer research. $3 1253664
650 0 $a Metabolic diseases. $3 1253620
650 0 $a Human physiology. $3 636012
650 0 $a Diabetes. $3 582755
650 0 $a Immunology. $3 592892
650 1 4 $a Cancer Research. $3 668358
650 2 4 $a Metabolic Diseases. $3 593967
650 2 4 $a Human Physiology. $3 668349
700 1 $a Nagaraju, Ganji Purnachandra. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1198408
700 1 $a BM Reddy, Aramati. $e editor. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1299009
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9789813293922
776 0 8 $i Printed edition: $z 9789813293946
776 0 8 $i Printed edition: $z 9789813293953
856 4 0 $u https://doi.org/10.1007/978-981-32-9393-9
912 $a ZDB-2-SBL
912 $a ZDB-2-SXB
950 $a Biomedical and Life Sciences (SpringerNature-11642)
950 $a Biomedical and Life Sciences (R0) (SpringerNature-43708)