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Proteomic and Ionomic Study for Identification of Biomarkers in Biological Fluid Samples of Patients with Psychiatric Disorders and Healthy Individuals

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Proteomic and Ionomic Study for Identification of Biomarkers in Biological Fluid Samples of Patients with Psychiatric Disorders and Healthy Individuals/ by Jemmyson Romário de Jesus.
Author:	de Jesus, Jemmyson Romário.
Description:	XXV, 88 p.online resource. :
Contained By:	Springer Nature eBook
Subject:	Analytical chemistry. -
Online resource:	https://doi.org/10.1007/978-3-030-29473-1
ISBN:	9783030294731

Proteomic and Ionomic Study for Identification of Biomarkers in Biological Fluid Samples of Patients with Psychiatric Disorders and Healthy Individuals
de Jesus, Jemmyson Romário.

Proteomic and Ionomic Study for Identification of Biomarkers in Biological Fluid Samples of Patients with Psychiatric Disorders and Healthy Individuals[electronic resource] /by Jemmyson Romário de Jesus. - 1st ed. 2019. - XXV, 88 p.online resource. - Springer Theses, Recognizing Outstanding Ph.D. Research,2190-5053. - Springer Theses, Recognizing Outstanding Ph.D. Research,.

Introduction -- Application of a Proteomic Strategy for the Identification of Differential Proteins Candidates to Biomarkers of Bipolar Disorder -- Application of the Ionomic Strategy to Evaluate Possible Differences in Metal Ion Concentration Between Patients with Bipolar Disorder and other Psychiatric Disorders -- Development of a New Polymer Membrane Based Methodology for Characterization of the Urine Proteome -- Final Conclusion. .

This book presents an exploratory analysis based on proteomic and ionomics studies comparing the blood serum of patients with bipolar disorder (BD), healthy controls, patients with schizophrenia (SCZ), and patients with other disorders (OD) in order to identify biomarkers of BD. Bipolar disorder is a psychiatric condition that affects thousands of people worldwide. The absence of biomarkers for BD has resulted in misdiagnosis and ineffective treatment in some patients, causing additional health problems and high costs for health systems. As such, this book evaluates various strategies for sample preparation for proteomic and ionomic studies in order to simplify complex serum samples and allow the quantification of chemical species (proteins and metal ions), which are potential candidates for BD biomarkers. In addition, it describes the development of a new membrane-based methodology for extracting urine proteins to be used in biomarker discovery.

ISBN: 9783030294731

Standard No.: 10.1007/978-3-030-29473-1doiSubjects--Topical Terms:

1182118
Analytical chemistry.

LC Class. No.: QD71-142

Dewey Class. No.: 543

Proteomic and Ionomic Study for Identification of Biomarkers in Biological Fluid Samples of Patients with Psychiatric Disorders and Healthy Individuals
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520 $a This book presents an exploratory analysis based on proteomic and ionomics studies comparing the blood serum of patients with bipolar disorder (BD), healthy controls, patients with schizophrenia (SCZ), and patients with other disorders (OD) in order to identify biomarkers of BD. Bipolar disorder is a psychiatric condition that affects thousands of people worldwide. The absence of biomarkers for BD has resulted in misdiagnosis and ineffective treatment in some patients, causing additional health problems and high costs for health systems. As such, this book evaluates various strategies for sample preparation for proteomic and ionomic studies in order to simplify complex serum samples and allow the quantification of chemical species (proteins and metal ions), which are potential candidates for BD biomarkers. In addition, it describes the development of a new membrane-based methodology for extracting urine proteins to be used in biomarker discovery.
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