國立虎尾科技大學 |

Carbohydrate-spiro-heterocycles

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Carbohydrate-spiro-heterocycles/ edited by László Somsák.
其他作者:	Somsák, László.
面頁冊數:	VII, 295 p. 1 illus.online resource. :
Contained By:	Springer Nature eBook
標題:	Organic chemistry. -
電子資源:	https://doi.org/10.1007/978-3-030-31942-7
ISBN:	9783030319427

Carbohydrate-spiro-heterocycles
Carbohydrate-spiro-heterocycles[electronic resource] /edited by László Somsák. - 1st ed. 2019. - VII, 295 p. 1 illus.online resource. - Topics in Heterocyclic Chemistry,571861-9282 ;. - Topics in Heterocyclic Chemistry,39.

Anomeric Spiro-Annulated Glycopyranosides: An Overview of Synthetic Methodologies and Biological Applications -- Cycloaddition Reactions of Sugar-Based Olefins, Nitrones and Nitrile Oxides: En Route to Saccharidic Spiroisoxazoli(di)nes -- Carbohydrate Spiro-heterocycles via Radical Chemistry -- Carbohydrate-Derived Spiroketals and Spirocyclic Lactones -- Cyanohydrins and Aminocyanides as Key Intermediates to Various Spiroheterocyclic Sugars -- Recent Advances in the Chemistry and Biology of Spirocyclic Nucleosides -- Spiroketal Phthalane C-Glycosides: Synthesis of Papulacandins and SGLT2 Inhibitors -- Spiro Iminosugars: Structural Diversity and Synthetic Strategies.

This volume is devoted to compounds in which the spiro centre is part of a pyranoid or furanoid or an iminosugar ring. The chapters contributed deal with methodological peculiarities of syntheses of natural and artificial sugar derived spirocycles as well as their biological applications and other utilities including marketed drugs. Carbohydrates are ubiquitous molecules in nature and participate in a vast number of biological interactions. Especially their conjugates with practically all kinds of primary and secondary metabolic small molecules (and also biomacromolecules) representing valuable tools for glycobiology research and also lead compounds for drug discovery. While monosaccharides per se appear as heterocycles, their natural conjugates frequently exhibit spiro(hetero)cyclic derivatives, in many cases of high therapeutical relevance. As a consequence, the field of carbohydrate-spiro-heterocycles attracts intense interest from both chemical and biomedical aspects therefore this volume will be of interest for synthetic and medicinal chemists and (glyco)biologists, as well as researchers involved in various biomedical fields.

ISBN: 9783030319427

Standard No.: 10.1007/978-3-030-31942-7doiSubjects--Topical Terms:

1148722
Organic chemistry.

LC Class. No.: QD415-436

Dewey Class. No.: 547

Carbohydrate-spiro-heterocycles
LDR:03222nam a22004095i 4500 001 1006784
003 DE-He213
005 20200629135631.0
007 cr nn 008mamaa
008 210106s2019 gw | s |||| 0|eng d
020 $a 9783030319427 $9 978-3-030-31942-7
024 7 $a 10.1007/978-3-030-31942-7 $2 doi
035 $a 978-3-030-31942-7
050 4 $a QD415-436
072 7 $a PNN $2 bicssc
072 7 $a SCI013040 $2 bisacsh
072 7 $a PNN $2 thema
082 0 4 $a 547 $2 23
245 1 0 $a Carbohydrate-spiro-heterocycles $h [electronic resource] / $c edited by László Somsák.
250 $a 1st ed. 2019.
264 1 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2019.
300 $a VII, 295 p. 1 illus. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
490 1 $a Topics in Heterocyclic Chemistry, $x 1861-9282 ; $v 57
505 0 $a Anomeric Spiro-Annulated Glycopyranosides: An Overview of Synthetic Methodologies and Biological Applications -- Cycloaddition Reactions of Sugar-Based Olefins, Nitrones and Nitrile Oxides: En Route to Saccharidic Spiroisoxazoli(di)nes -- Carbohydrate Spiro-heterocycles via Radical Chemistry -- Carbohydrate-Derived Spiroketals and Spirocyclic Lactones -- Cyanohydrins and Aminocyanides as Key Intermediates to Various Spiroheterocyclic Sugars -- Recent Advances in the Chemistry and Biology of Spirocyclic Nucleosides -- Spiroketal Phthalane C-Glycosides: Synthesis of Papulacandins and SGLT2 Inhibitors -- Spiro Iminosugars: Structural Diversity and Synthetic Strategies.
520 $a This volume is devoted to compounds in which the spiro centre is part of a pyranoid or furanoid or an iminosugar ring. The chapters contributed deal with methodological peculiarities of syntheses of natural and artificial sugar derived spirocycles as well as their biological applications and other utilities including marketed drugs. Carbohydrates are ubiquitous molecules in nature and participate in a vast number of biological interactions. Especially their conjugates with practically all kinds of primary and secondary metabolic small molecules (and also biomacromolecules) representing valuable tools for glycobiology research and also lead compounds for drug discovery. While monosaccharides per se appear as heterocycles, their natural conjugates frequently exhibit spiro(hetero)cyclic derivatives, in many cases of high therapeutical relevance. As a consequence, the field of carbohydrate-spiro-heterocycles attracts intense interest from both chemical and biomedical aspects therefore this volume will be of interest for synthetic and medicinal chemists and (glyco)biologists, as well as researchers involved in various biomedical fields.
650 0 $a Organic chemistry. $3 1148722
650 0 $a Medicinal chemistry. $3 1253747
650 0 $a Biochemistry. $3 582831
650 0 $a Biomedical engineering. $3 588770
650 0 $a Chemical engineering. $3 555952
650 1 4 $a Organic Chemistry. $3 673440
650 2 4 $a Medicinal Chemistry. $3 668872
650 2 4 $a Biochemistry, general. $3 593881
650 2 4 $a Biomedical Engineering/Biotechnology. $3 1068811
650 2 4 $a Industrial Chemistry/Chemical Engineering. $3 671153
700 1 $a Somsák, László. $e editor. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1300415
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9783030319410
776 0 8 $i Printed edition: $z 9783030319434
776 0 8 $i Printed edition: $z 9783030319441
830 0 $a Topics in Heterocyclic Chemistry, $x 1861-9282 ; $v 39 $3 1254746
856 4 0 $u https://doi.org/10.1007/978-3-030-31942-7
912 $a ZDB-2-CMS
912 $a ZDB-2-SXC
950 $a Chemistry and Materials Science (SpringerNature-11644)
950 $a Chemistry and Material Science (R0) (SpringerNature-43709)