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Study of Bacteriorhodopsin in a Cont...
~
Yeh, Vivien.
Study of Bacteriorhodopsin in a Controlled Lipid Environment
紀錄類型:
書目-語言資料,印刷品 : Monograph/item
正題名/作者:
Study of Bacteriorhodopsin in a Controlled Lipid Environment/ by Vivien Yeh.
作者:
Yeh, Vivien.
面頁冊數:
XVIII, 139 p. 82 illus., 64 illus. in color.online resource. :
Contained By:
Springer Nature eBook
標題:
Physical chemistry. -
電子資源:
https://doi.org/10.1007/978-981-13-1238-0
ISBN:
9789811312380
Study of Bacteriorhodopsin in a Controlled Lipid Environment
Yeh, Vivien.
Study of Bacteriorhodopsin in a Controlled Lipid Environment
[electronic resource] /by Vivien Yeh. - 1st ed. 2019. - XVIII, 139 p. 82 illus., 64 illus. in color.online resource. - Springer Theses, Recognizing Outstanding Ph.D. Research,2190-5053. - Springer Theses, Recognizing Outstanding Ph.D. Research,.
Introduction -- Experimental Background -- Effect of Lipid Composition of Nanodisc -- Effect of Size of Nanodisc -- Native Membrane Nanodisc -- Conclusions and Outlook -- References -- Appendix.
This book focuses on the study of how the properties of nanodiscs, such as lipid composition and size, influence the function of the embedding integral membrane protein, bacteriorhodopsin. The author performed systematic studies to show that the lipid composition and the charge of the hydrophobic head and the structure of hydrophilic tails affect the photocycle pathway of bacteriorhodopsin, which is closely associated with its proton-pumping activity. Furthermore, the author demonstrated a highly efficient method for extracting membrane proteins directly from the biological membrane, preserving protein conformation, function and essential native lipids. This book demonstrates optimization and sample preparation, and presents practical methods of preparing membrane protein-embedded nanodisc samples for biophysical studies, which benefit structural and functional studies in the field of membrane protein characterization, both.
ISBN: 9789811312380
Standard No.: 10.1007/978-981-13-1238-0doiSubjects--Topical Terms:
1148725
Physical chemistry.
LC Class. No.: QD450-882
Dewey Class. No.: 541
Study of Bacteriorhodopsin in a Controlled Lipid Environment
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