國立虎尾科技大學 |

Molecular Mechanisms of Inflammation: Induction, Resolution and Escape by Helicobacter pylori

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Molecular Mechanisms of Inflammation: Induction, Resolution and Escape by Helicobacter pylori/ edited by Steffen Backert.
其他作者:	Backert, Steffen.
面頁冊數:	XXIV, 359 p. 29 illus., 28 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Immunology. -
電子資源:	https://doi.org/10.1007/978-3-030-15138-6
ISBN:	9783030151386

Molecular Mechanisms of Inflammation: Induction, Resolution and Escape by Helicobacter pylori
Molecular Mechanisms of Inflammation: Induction, Resolution and Escape by Helicobacter pylori[electronic resource] /edited by Steffen Backert. - 1st ed. 2019. - XXIV, 359 p. 29 illus., 28 illus. in color.online resource. - Current Topics in Microbiology and Immunology,4210070-217X ;. - Current Topics in Microbiology and Immunology,387.

Inflammation, immunity and vaccine development for the gastric pathogen Helicobacter pylori -- Impact of Helicobacter pylori Virulence Factors on the Host immune Response and Gastric Pathology -- Genetic polymorphisms in inflammatory and other regulators in gastric cancer: risks and clinical consequences -- MALT lymphoma as a model of chronic inflammation-induced gastric tumor development -- Crosstalk between DNA damage and inflammation in the multiple steps of gastric carcinogenesis -- Importance of toll-like receptors in pro-inflammatory and anti-inflammatory responses by Helicobacter pylori infection -- Role of NOD1 and ALPK1/TIFA signalling in innate immunity against Helicobacter pylori infection -- Carbohydrate-dependent and antimicrobial peptide defense mechanisms against Helicobacter pylori infections -- The sweeping role of cholesterol depletion in the persistence of Helicobacter pylori infections -- Helicobacter pylori deregulates T and B cell signaling to trigger immune evasion -- Mechanisms of inflammasome signaling, microRNA induction and resolution of inflammation by Helicobacter pylori -- Impact of the gastrointestinal microbiome in health and disease: co-evolution with the host immune system -- Resolution of gastric cancer-promoting inflammation: a novel strategy for anti-cancer therapy.

This book focuses on immune reactions and interactions of humans with Helicobacter pylori - a human pathogen connected to gastritis, peptic ulcers and even gastric cancer. With nearly half of the world’s population colonized, it has been characterized as one of the most successful pathogens for more than 100,000 years of co-evolution with its host. The respective chapters discuss not only how H. pylori infection is considered a paradigm for persistent bacterial infection and chronic inflammation, but also how the infection might be connected to host protection against gastro-esophageal diseases, asthma, and other allergic disease manifestations. Readers will gain essential insights into the roles of specific factors in the immune response and learn about the impact of genetic polymorphisms on the risk of gastric carcinogenesis. In addition, the book discusses the strategies used by this bacterium, which allow it to colonize specific sites in the stomach, interact with the microbiome, evade immune surveillance and undermine the resolution of inflammation during persistent infection. This volume presents a concise summary of recent advances in the areas of induction, resolution and escape of inflammation, innate and adaptive immunity, gastric disease development, as well as treatment and vaccination against H. pylori. Accordingly, it offers a valuable asset for scientists and clinicians alike.

ISBN: 9783030151386

Standard No.: 10.1007/978-3-030-15138-6doiSubjects--Topical Terms:

592892
Immunology.

LC Class. No.: QR180-189.5

Dewey Class. No.: 616.079

Molecular Mechanisms of Inflammation: Induction, Resolution and Escape by Helicobacter pylori
LDR:04239nam a22004095i 4500 001 1009797
003 DE-He213
005 20200704105021.0
007 cr nn 008mamaa
008 210106s2019 gw | s |||| 0|eng d
020 $a 9783030151386 $9 978-3-030-15138-6
024 7 $a 10.1007/978-3-030-15138-6 $2 doi
035 $a 978-3-030-15138-6
050 4 $a QR180-189.5
072 7 $a MJCM $2 bicssc
072 7 $a MED044000 $2 bisacsh
072 7 $a MJCM $2 thema
082 0 4 $a 616.079 $2 23
245 1 0 $a Molecular Mechanisms of Inflammation: Induction, Resolution and Escape by Helicobacter pylori $h [electronic resource] / $c edited by Steffen Backert.
250 $a 1st ed. 2019.
264 1 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2019.
300 $a XXIV, 359 p. 29 illus., 28 illus. in color. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
490 1 $a Current Topics in Microbiology and Immunology, $x 0070-217X ; $v 421
505 0 $a Inflammation, immunity and vaccine development for the gastric pathogen Helicobacter pylori -- Impact of Helicobacter pylori Virulence Factors on the Host immune Response and Gastric Pathology -- Genetic polymorphisms in inflammatory and other regulators in gastric cancer: risks and clinical consequences -- MALT lymphoma as a model of chronic inflammation-induced gastric tumor development -- Crosstalk between DNA damage and inflammation in the multiple steps of gastric carcinogenesis -- Importance of toll-like receptors in pro-inflammatory and anti-inflammatory responses by Helicobacter pylori infection -- Role of NOD1 and ALPK1/TIFA signalling in innate immunity against Helicobacter pylori infection -- Carbohydrate-dependent and antimicrobial peptide defense mechanisms against Helicobacter pylori infections -- The sweeping role of cholesterol depletion in the persistence of Helicobacter pylori infections -- Helicobacter pylori deregulates T and B cell signaling to trigger immune evasion -- Mechanisms of inflammasome signaling, microRNA induction and resolution of inflammation by Helicobacter pylori -- Impact of the gastrointestinal microbiome in health and disease: co-evolution with the host immune system -- Resolution of gastric cancer-promoting inflammation: a novel strategy for anti-cancer therapy.
520 $a This book focuses on immune reactions and interactions of humans with Helicobacter pylori - a human pathogen connected to gastritis, peptic ulcers and even gastric cancer. With nearly half of the world’s population colonized, it has been characterized as one of the most successful pathogens for more than 100,000 years of co-evolution with its host. The respective chapters discuss not only how H. pylori infection is considered a paradigm for persistent bacterial infection and chronic inflammation, but also how the infection might be connected to host protection against gastro-esophageal diseases, asthma, and other allergic disease manifestations. Readers will gain essential insights into the roles of specific factors in the immune response and learn about the impact of genetic polymorphisms on the risk of gastric carcinogenesis. In addition, the book discusses the strategies used by this bacterium, which allow it to colonize specific sites in the stomach, interact with the microbiome, evade immune surveillance and undermine the resolution of inflammation during persistent infection. This volume presents a concise summary of recent advances in the areas of induction, resolution and escape of inflammation, innate and adaptive immunity, gastric disease development, as well as treatment and vaccination against H. pylori. Accordingly, it offers a valuable asset for scientists and clinicians alike.
650 0 $a Immunology. $3 592892
650 0 $a Medical microbiology. $3 583124
650 0 $a Gastroenterology . $3 1254565
650 0 $a Human physiology. $3 636012
650 2 4 $a Medical Microbiology. $3 668401
650 2 4 $a Gastroenterology. $3 673684
650 2 4 $a Human Physiology. $3 668349
700 1 $a Backert, Steffen. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 889235
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9783030151379
776 0 8 $i Printed edition: $z 9783030151393
776 0 8 $i Printed edition: $z 9783030151409
830 0 $a Current Topics in Microbiology and Immunology, $x 0070-217X ; $v 387 $3 1254330
856 4 0 $u https://doi.org/10.1007/978-3-030-15138-6
912 $a ZDB-2-SBL
912 $a ZDB-2-SXB
950 $a Biomedical and Life Sciences (SpringerNature-11642)
950 $a Biomedical and Life Sciences (R0) (SpringerNature-43708)