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Biophysics of RNA-Protein Interactions = A Mechanistic View /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Biophysics of RNA-Protein Interactions/ edited by Chirlmin Joo, David Rueda.
其他題名:	A Mechanistic View /
其他作者:	Joo, Chirlmin.
面頁冊數:	VII, 249 p. 77 illus., 74 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Biophysics. -
電子資源:	https://doi.org/10.1007/978-1-4939-9726-8
ISBN:	9781493997268

Biophysics of RNA-Protein Interactions = A Mechanistic View /
Biophysics of RNA-Protein InteractionsA Mechanistic View /[electronic resource] :edited by Chirlmin Joo, David Rueda. - 1st ed. 2019. - VII, 249 p. 77 illus., 74 illus. in color.online resource. - Biological and Medical Physics, Biomedical Engineering,1618-7210. - Biological and Medical Physics, Biomedical Engineering,.

Part 1: RNA Binding Proteins -- Chapter 1: How proteins recognize RNA -- Chapter 2: The interaction between L7Ae family of proteins and RNA kink turns -- Chapter 3: Evolving methods in defining the role of RNA in RNP assembly -- Chapter 4: Single-molecule studies of exonuclease: Following cleavage actions one step at a time -- Chapter 5: Fitting in the age of single-molecule experiments: A guide to maximum-likelihood estimation and its advantages -- Part II: Transcription and Translation -- Chapter 6: A single-molecule view on cellular and viral RNA synthesis -- Chapter 7: Single-Molecule Optical Tweezers Studies of Translation -- Part III: RNA-Guided Protein Machineries -- Chapter 8: Biophysical and biochemical approaches in the analysis of Argonaute-miRNA complexes -- Chapter 9: Biophysics of RNA-guided CRISPR immunity -- Chapter 10: Dynamics of MicroRNA Biogenesis.

RNA molecules play key roles in all aspects of cellular life, but to do so efficiently, they must work in synergism with proteins. This book addresses how proteins and RNA interact to carry out biological functions such as protein synthesis, regulation of gene expression, genome defense, liquid phase separation and more. The topics addressed in this volume will appeal to researchers in biophysics, biochemistry and structural biology. The book is a useful resource for anybody interested in elucidating the molecular mechanisms and discrete properties of RNA-protein complexes. Included are reviews of key systems such as microRNA and CRISPR/Cas that exemplify how RNA and proteins work together to perform their biological function. Also covered are techniques ranging from single molecule fluorescence and force spectroscopy to crystallography, cryo-EM microscopy, and kinetic modeling.

ISBN: 9781493997268

Standard No.: 10.1007/978-1-4939-9726-8doiSubjects--Topical Terms:

581576
Biophysics.

LC Class. No.: QH505

Dewey Class. No.: 571.4

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