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A Practical Guide to Pharmacological Biotechnology

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	A Practical Guide to Pharmacological Biotechnology/ by Jayanta Kumar Patra, Swagat Kumar Das, Gitishree Das, Hrudayanath Thatoi.
作者:	Patra, Jayanta Kumar.
其他作者:	Das, Swagat Kumar.
面頁冊數:	XIII, 142 p. 50 illus., 39 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Laboratory medicine. -
電子資源:	https://doi.org/10.1007/978-981-13-6355-9
ISBN:	9789811363559

A Practical Guide to Pharmacological Biotechnology
Patra, Jayanta Kumar.

A Practical Guide to Pharmacological Biotechnology[electronic resource] /by Jayanta Kumar Patra, Swagat Kumar Das, Gitishree Das, Hrudayanath Thatoi. - 1st ed. 2019. - XIII, 142 p. 50 illus., 39 illus. in color.online resource. - Learning Materials in Biosciences,2509-6125. - Learning Materials in Biosciences,1.

Part1.Introduction -- 1.1 Rules of laboratory safety in a pharmacology laboratory -- 1.2 Commom instruments and their uses used in a pharmacology laboratory -- Part2.General aspects of Pharmacology laboratory -- 2.1 Safety and Risk assessment -- 2.2 Use and Handling of laboratory animals -- 2.3 Experimental design -- 2.4 Essential statistics -- 2.5 Cumulative Dose Response Curve -- 2.6 Toxicology -- 2.7 Basic instruments and techniques in Pharmacology Laboratory -- Part3.Isolated tissues and organs -- 3.1 Basic instruments used for isolated tissue experiments -- 3.2 Organ baths -- 3.3 Smooth muscle preparations -- 3.4 Skeletal muscle preparations -- 3.5 Cardiac muscle preparations -- Part4.Isolated tissues for screening of drugs -- 4.1 Evaluation of antidiabetic agents -- 4.2 Evaluation of antidepressants -- 4.3 Evaluation of antihypertensive agents -- 4.4 Evaluation of antiulcer agents -- 4.5 Evaluation of hepatotoxicity -- 4.6 Evaluation of Antioxidant agents -- 4.7 Evaluation of local anaesthetics -- Part5.Genotoxicity and Toxicological studies -- 5.1 The Mouse Lymphoma Assay -- 5.2 The Comet Assay -- 5.3 In vitro Genotoxicity assay -- 5.4 In vitro Teratogenicity Testing -- 5.5 Histopathological studies of animal tissues -- 5.6 Drug poisoning -- Part6.Experimental Animal studies -- 6.1 Pyrogen testing -- 6.2 Collecting blood from mice -- 6.3 Studies on different parameters of blood -- 6.4 Experiment on central nervous system -- 6.5 Evaluation on cardiovascular system -- 6.6 Experiments on GI tract -- Part7.Clinical trials -- 7.1 Clinical Pharmacology and its genesis -- 7.2 National and International agencies and their role in Clinical pharmacology -- 7.3 Stages in drug development and clinical trials -- 7.4 Ethics in Clinical research -- 7.5 Safety assessment in Clinical trials -- Part8.IPR and ethics in animal studies -- 8.1 Intellectual property rights and its different categories -- 8.2 Importance of IPR in drug development -- 8.3 Patenting cells, cell lines and animals -- 8.4 Ethics in laboratory animal studies -- 8.5 Risk assessment and management -- 8.6 Good laboratory practices.

Pharmacological biotechnology is applied to and used to study drug development, working mechanisms, diagnosis, and therapies. This manual is the textbook covering the whole range of experiments related to pharmacology. It also contains basic laboratory safety guidelines along with the basic calculations and formulas used in a laboratory. Each chapter starts with an introduction/theory into the basic approach followed by detailed methods sections with easy-to-follow protocols and comprehensive troubleshooting, calculations and possible questions for examination. The target group is researchers who are studying pharmacological biotechnology in the laboratory.

ISBN: 9789811363559

Standard No.: 10.1007/978-981-13-6355-9doiSubjects--Topical Terms:

1254567
Laboratory medicine.

LC Class. No.: R108

Dewey Class. No.: 610.724

A Practical Guide to Pharmacological Biotechnology
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