國立虎尾科技大學 |

Molecular Diagnostics = Part 1: Technical Backgrounds and Quality Aspects /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Molecular Diagnostics/ edited by E. van Pelt-Verkuil, W.B. van Leeuwen, R. te Witt.
Reminder of title:	Part 1: Technical Backgrounds and Quality Aspects /
other author:	van Pelt-Verkuil, E.
Description:	VII, 457 p. 224 illus., 205 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Laboratory medicine. -
Online resource:	https://doi.org/10.1007/978-981-13-1604-3
ISBN:	9789811316043

Molecular Diagnostics = Part 1: Technical Backgrounds and Quality Aspects /
Molecular DiagnosticsPart 1: Technical Backgrounds and Quality Aspects /[electronic resource] :edited by E. van Pelt-Verkuil, W.B. van Leeuwen, R. te Witt. - 1st ed. 2019. - VII, 457 p. 224 illus., 205 illus. in color.online resource.

The importance of nucleic acids in diagnostics -- Background and analysis of nucleic acids -- Primers and probes -- Basic principles of nucleic acid hybridisation -- Principles of PCR -- Quality assurance, management and control in molecular diagnostics -- Quantitative isothermal molecular amplification techniques -- DNA sequencing -- Bioinformatics -- The ongoing revolution of MALDI TOF Mass Spectrometry for Molecular Diagnostics -- Information in the amplification curve.

The books Molecular Diagnostics Part 1 and 2 provide a comprehensive and practical overview of the state-of-the-art molecular biological diagnostic strategies that are being used in a wide variety of disciplines. The editors and experts in their respective fields have combined their knowledge to write these two books. Many years of experience in the development, application and quality control of molecular diagnostic methods is reflected herewith. Molecular Diagnostics Part 1 is dedicated to the theoretical backgrounds of the technologies often applied in molecular diagnostics, in which nucleic acid amplification methods (such as real-time PCR), sequencing and bioinformatics are the basic tools. The assay design and -development, combined with items of trouble-shooting are described in detail. As a foundation of reliable molecular diagnostic assays, the quality control required for validation, implementation and performance of molecular diagnostic assays is thoroughly discussed. This book also provides extensive information for those working with molecular techniques in a wide variety of research applications using conventional and real-time PCR technology, Sanger and high throughput sequencing techniques, and bioinformatics. Molecular Diagnostics Part 2 highlights the applications of the molecular diagnostic methods in the various diagnostic laboratories, comprising: - Clinical microbiology - Clinical chemistry - Clinical genetics - Clinical pathology - Molecular hematopathology - Veterinary health - Plant health - Food safety Both full-color and well-illustrated books are particularly valuable for students, clinicians, scientists and other professionals who are interested in (designing) molecular diagnostic methods and for those who wish to broaden their knowledge on the current molecular biological revolution. The information in the books highlights the trend of the integration of multiple (clinical) disciplines into one universal molecular laboratory. .

ISBN: 9789811316043

Standard No.: 10.1007/978-981-13-1604-3doiSubjects--Topical Terms:

1254567
Laboratory medicine.

LC Class. No.: R108

Dewey Class. No.: 610.724

Molecular Diagnostics = Part 1: Technical Backgrounds and Quality Aspects /
LDR:03838nam a22003855i 4500 001 1012974
003 DE-He213
005 20200706125734.0
007 cr nn 008mamaa
008 210106s2019 si | s |||| 0|eng d
020 $a 9789811316043 $9 978-981-13-1604-3
024 7 $a 10.1007/978-981-13-1604-3 $2 doi
035 $a 978-981-13-1604-3
050 4 $a R108
072 7 $a MBGL $2 bicssc
072 7 $a MED047000 $2 bisacsh
072 7 $a MBGL $2 thema
082 0 4 $a 610.724 $2 23
245 1 0 $a Molecular Diagnostics $h [electronic resource] : $b Part 1: Technical Backgrounds and Quality Aspects / $c edited by E. van Pelt-Verkuil, W.B. van Leeuwen, R. te Witt.
250 $a 1st ed. 2019.
264 1 $a Singapore : $b Springer Singapore : $b Imprint: Springer, $c 2019.
300 $a VII, 457 p. 224 illus., 205 illus. in color. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
505 0 $a The importance of nucleic acids in diagnostics -- Background and analysis of nucleic acids -- Primers and probes -- Basic principles of nucleic acid hybridisation -- Principles of PCR -- Quality assurance, management and control in molecular diagnostics -- Quantitative isothermal molecular amplification techniques -- DNA sequencing -- Bioinformatics -- The ongoing revolution of MALDI TOF Mass Spectrometry for Molecular Diagnostics -- Information in the amplification curve.
520 $a The books Molecular Diagnostics Part 1 and 2 provide a comprehensive and practical overview of the state-of-the-art molecular biological diagnostic strategies that are being used in a wide variety of disciplines. The editors and experts in their respective fields have combined their knowledge to write these two books. Many years of experience in the development, application and quality control of molecular diagnostic methods is reflected herewith. Molecular Diagnostics Part 1 is dedicated to the theoretical backgrounds of the technologies often applied in molecular diagnostics, in which nucleic acid amplification methods (such as real-time PCR), sequencing and bioinformatics are the basic tools. The assay design and -development, combined with items of trouble-shooting are described in detail. As a foundation of reliable molecular diagnostic assays, the quality control required for validation, implementation and performance of molecular diagnostic assays is thoroughly discussed. This book also provides extensive information for those working with molecular techniques in a wide variety of research applications using conventional and real-time PCR technology, Sanger and high throughput sequencing techniques, and bioinformatics. Molecular Diagnostics Part 2 highlights the applications of the molecular diagnostic methods in the various diagnostic laboratories, comprising: - Clinical microbiology - Clinical chemistry - Clinical genetics - Clinical pathology - Molecular hematopathology - Veterinary health - Plant health - Food safety Both full-color and well-illustrated books are particularly valuable for students, clinicians, scientists and other professionals who are interested in (designing) molecular diagnostic methods and for those who wish to broaden their knowledge on the current molecular biological revolution. The information in the books highlights the trend of the integration of multiple (clinical) disciplines into one universal molecular laboratory. .
650 0 $a Laboratory medicine. $3 1254567
650 0 $a Agriculture. $3 660421
650 0 $a Pathology. $3 668553
650 1 4 $a Laboratory Medicine. $3 673604
700 1 $a van Pelt-Verkuil, E. $e editor. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1307280
700 1 $a van Leeuwen, W.B. $e editor. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1307281
700 1 $a te Witt, R. $e editor. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1307282
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9789811316036
776 0 8 $i Printed edition: $z 9789811316050
856 4 0 $u https://doi.org/10.1007/978-981-13-1604-3
912 $a ZDB-2-SBL
912 $a ZDB-2-SXB
950 $a Biomedical and Life Sciences (SpringerNature-11642)
950 $a Biomedical and Life Sciences (R0) (SpringerNature-43708)