Language:
English
繁體中文
Help
Login
Back
Switch To:
Labeled
|
MARC Mode
|
ISBD
Molecular Genetics of Inflammatory B...
~
Rioux, John D.
Molecular Genetics of Inflammatory Bowel Disease
Record Type:
Language materials, printed : Monograph/item
Title/Author:
Molecular Genetics of Inflammatory Bowel Disease/ edited by Charlotte Hedin, John D. Rioux, Mauro D'Amato.
other author:
Hedin, Charlotte.
Description:
X, 402 p. 37 illus., 35 illus. in color.online resource. :
Contained By:
Springer Nature eBook
Subject:
Human genetics. -
Online resource:
https://doi.org/10.1007/978-3-030-28703-0
ISBN:
9783030287030
Molecular Genetics of Inflammatory Bowel Disease
Molecular Genetics of Inflammatory Bowel Disease
[electronic resource] /edited by Charlotte Hedin, John D. Rioux, Mauro D'Amato. - 2nd ed. 2019. - X, 402 p. 37 illus., 35 illus. in color.online resource.
Part 1: The Foundation of IBD Genetics, Human and Animal Studies -- A Primer on IBD: Phenotypes, Diagnosis, Treatment and Clinical Challenges -- Genetic Epidemiology of Inflammatory Bowel Disease, Early Twin and Family Studies -- Insights from Recent Advances in Animal Models of Inflammatory Bowel Disease -- Part 2: The Genetic and Molecular Makeup of Inflammatory Bowel Disease -- Complex Disease Genes and their Discovery -- The Genetics of Crohn's Disease -- Genetics of Ulcerative Colitis -- Genetic Overlap between Inflammatory Bowel Disease and Other Diseases -- Molecular Profiling of IBD Subtypes/Response to Therapy -- Epigenetics of Inflammatory Bowel Disease -- Part 3: Pathogenetic Pathways in Inflammatory Bowel Disease -- Nod1 and Nod2 and the Immune Response to Bacteria -- The IL-23-Th17 Axis in Intestinal Inflammation -- Inflammatory Bowel Disease at the Intersection of Autophagy and Immunity: Insights from Human Genetics -- The Epithelial Barrier -- Host Interactions with Bacteria: From “Entente Cordiale” to “Casus Belli” -- Cytokines in Inflammatory Bowel Disease -- Part 4: Concluding Remarks and Future Perspectives -- Towards Personalized Therapy in Inflammatory Bowel Disease -- Index.
Inflammatory bowel disease (IBD) affects 1% of people worldwide. This condition is partly inherited, and genetic research has made enormous progress during the last few years, providing important insight into disease pathogenesis. This book provides a concise but complete overview of existing knowledge, with particular focus on the molecular and genetic mechanisms at the basis of IBD. Invited experts, at the frontline of IBD research, introduce basic concepts in the pathophysiology of IBD and its two major forms Crohn’s disease and ulcerative colitis, provide a historical perspective and highlight latest discoveries of IBD genetic research, describe how this information has helped to unravel novel pathogenetic pathways, and formulate a vision for future investigations and their clinical application in IBD. State-of-the-art information contained in this book is an exceptional resource for all those in the biomedical field with a specific interest in IBD, including basic scientists, gastroenterologists, GI specialist doctors and research nurses, but also medical and biomedical students.
ISBN: 9783030287030
Standard No.: 10.1007/978-3-030-28703-0doiSubjects--Topical Terms:
596505
Human genetics.
LC Class. No.: RB155-155.8
Dewey Class. No.: 611.01816
Molecular Genetics of Inflammatory Bowel Disease
LDR
:03777nam a22004215i 4500
001
1014882
003
DE-He213
005
20200705091737.0
007
cr nn 008mamaa
008
210106s2019 gw | s |||| 0|eng d
020
$a
9783030287030
$9
978-3-030-28703-0
024
7
$a
10.1007/978-3-030-28703-0
$2
doi
035
$a
978-3-030-28703-0
050
4
$a
RB155-155.8
050
4
$a
QH431
072
7
$a
MFN
$2
bicssc
072
7
$a
MED107000
$2
bisacsh
072
7
$a
MFN
$2
thema
082
0 4
$a
611.01816
$2
23
082
0 4
$a
599.935
$2
23
245
1 0
$a
Molecular Genetics of Inflammatory Bowel Disease
$h
[electronic resource] /
$c
edited by Charlotte Hedin, John D. Rioux, Mauro D'Amato.
250
$a
2nd ed. 2019.
264
1
$a
Cham :
$b
Springer International Publishing :
$b
Imprint: Springer,
$c
2019.
300
$a
X, 402 p. 37 illus., 35 illus. in color.
$b
online resource.
336
$a
text
$b
txt
$2
rdacontent
337
$a
computer
$b
c
$2
rdamedia
338
$a
online resource
$b
cr
$2
rdacarrier
347
$a
text file
$b
PDF
$2
rda
505
0
$a
Part 1: The Foundation of IBD Genetics, Human and Animal Studies -- A Primer on IBD: Phenotypes, Diagnosis, Treatment and Clinical Challenges -- Genetic Epidemiology of Inflammatory Bowel Disease, Early Twin and Family Studies -- Insights from Recent Advances in Animal Models of Inflammatory Bowel Disease -- Part 2: The Genetic and Molecular Makeup of Inflammatory Bowel Disease -- Complex Disease Genes and their Discovery -- The Genetics of Crohn's Disease -- Genetics of Ulcerative Colitis -- Genetic Overlap between Inflammatory Bowel Disease and Other Diseases -- Molecular Profiling of IBD Subtypes/Response to Therapy -- Epigenetics of Inflammatory Bowel Disease -- Part 3: Pathogenetic Pathways in Inflammatory Bowel Disease -- Nod1 and Nod2 and the Immune Response to Bacteria -- The IL-23-Th17 Axis in Intestinal Inflammation -- Inflammatory Bowel Disease at the Intersection of Autophagy and Immunity: Insights from Human Genetics -- The Epithelial Barrier -- Host Interactions with Bacteria: From “Entente Cordiale” to “Casus Belli” -- Cytokines in Inflammatory Bowel Disease -- Part 4: Concluding Remarks and Future Perspectives -- Towards Personalized Therapy in Inflammatory Bowel Disease -- Index.
520
$a
Inflammatory bowel disease (IBD) affects 1% of people worldwide. This condition is partly inherited, and genetic research has made enormous progress during the last few years, providing important insight into disease pathogenesis. This book provides a concise but complete overview of existing knowledge, with particular focus on the molecular and genetic mechanisms at the basis of IBD. Invited experts, at the frontline of IBD research, introduce basic concepts in the pathophysiology of IBD and its two major forms Crohn’s disease and ulcerative colitis, provide a historical perspective and highlight latest discoveries of IBD genetic research, describe how this information has helped to unravel novel pathogenetic pathways, and formulate a vision for future investigations and their clinical application in IBD. State-of-the-art information contained in this book is an exceptional resource for all those in the biomedical field with a specific interest in IBD, including basic scientists, gastroenterologists, GI specialist doctors and research nurses, but also medical and biomedical students.
650
0
$a
Human genetics.
$3
596505
650
0
$a
Molecular biology.
$3
583443
650
0
$a
Gastroenterology .
$3
1254565
650
1 4
$a
Human Genetics.
$3
593893
650
2 4
$a
Molecular Medicine.
$3
668353
650
2 4
$a
Gastroenterology.
$3
673684
700
1
$a
Hedin, Charlotte.
$e
editor.
$4
edt
$4
http://id.loc.gov/vocabulary/relators/edt
$3
1309024
700
1
$a
Rioux, John D.
$4
edt
$4
http://id.loc.gov/vocabulary/relators/edt
$3
1078727
700
1
$a
D'Amato, Mauro.
$4
edt
$4
http://id.loc.gov/vocabulary/relators/edt
$3
1078726
710
2
$a
SpringerLink (Online service)
$3
593884
773
0
$t
Springer Nature eBook
776
0 8
$i
Printed edition:
$z
9783030287023
776
0 8
$i
Printed edition:
$z
9783030287047
776
0 8
$i
Printed edition:
$z
9783030287054
856
4 0
$u
https://doi.org/10.1007/978-3-030-28703-0
912
$a
ZDB-2-SBL
912
$a
ZDB-2-SXB
950
$a
Biomedical and Life Sciences (SpringerNature-11642)
950
$a
Biomedical and Life Sciences (R0) (SpringerNature-43708)
based on 0 review(s)
Multimedia
Reviews
Add a review
and share your thoughts with other readers
Export
pickup library
Processing
...
Change password
Login