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Interaction of Nanomaterials with the Immune System

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Interaction of Nanomaterials with the Immune System/ edited by James C. Bonner, Jared M. Brown.
其他作者:	Brown, Jared M.
面頁冊數:	X, 223 p. 16 illus., 5 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Pharmacology/Toxicology. -
電子資源:	https://doi.org/10.1007/978-3-030-33962-3
ISBN:	9783030339623

Interaction of Nanomaterials with the Immune System
Interaction of Nanomaterials with the Immune System[electronic resource] /edited by James C. Bonner, Jared M. Brown. - 1st ed. 2020. - X, 223 p. 16 illus., 5 illus. in color.online resource. - Molecular and Integrative Toxicology,2168-4219. - Molecular and Integrative Toxicology,.

Overview of immune response to nanomaterials caused by either inhalation, oral, or dermal exposure -- Engineered nanomaterials: synthesis, characterization, uses and exposure -- Impact of nanomaterials on barrier function -- Complement activation and inflammation -- Macrophage function and phagocytosis -- Mast cells -- Impact on dendritic cell - lymphocyte function -- Impact on host pathogen response and microbiome -- Allergy/autoimmunity -- Pre-existing allergic or bacterial-induced lung disease -- Nanomaterial effects on viral infection -- Immunotoxicity and carcinogenesis -- In vivo animal models (nude mice, transgenic models) -- In vitro cell culture models -- In silico computational modeling -- Summary of mechanisms of immune modulation. .

This book covers the latest information related to understanding immune responses to engineered nanomaterials (ENMs). Many ENMs used in both the consumer and biomedical fields have been reported to elicit adverse immune responses ranging from innate immune responses such as complement activation to changes in adaptive immunity that influence pathogen responses and promote disease states such as asthma. Interaction of Nanomaterials with the Immune System covers the most up to date information on our understanding of immune responses to ENMs across a wide range of topics including innate immunity, allergic immune responses, adaptive provides the reader with (1) up to date understanding of immune responses to ENMs; (2) current testing methods; and (3) appropriate models including alternative testing strategies for evaluating immunotoxicity of ENMs. .

ISBN: 9783030339623

Standard No.: 10.1007/978-3-030-33962-3doiSubjects--Topical Terms:

593882
Pharmacology/Toxicology.

LC Class. No.: RM1-950

Dewey Class. No.: 615

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