國立虎尾科技大學 |

Ketamine = From Abused Drug to Rapid-Acting Antidepressant /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Ketamine/ edited by Kenji Hashimoto, Soichiro Ide, Kazutaka Ikeda.
Reminder of title:	From Abused Drug to Rapid-Acting Antidepressant /
other author:	Hashimoto, Kenji.
Description:	V, 189 p. 27 illus., 13 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Neurosciences. -
Online resource:	https://doi.org/10.1007/978-981-15-2902-3
ISBN:	9789811529023

Ketamine = From Abused Drug to Rapid-Acting Antidepressant /
KetamineFrom Abused Drug to Rapid-Acting Antidepressant /[electronic resource] :edited by Kenji Hashimoto, Soichiro Ide, Kazutaka Ikeda. - 1st ed. 2020. - V, 189 p. 27 illus., 13 illus. in color.online resource.

1.Determination of ketamine in the river of China -- 2.Ketamine abuse in Taiwan -- 3.Ketamine problem in Hong Kong -- 4. Hair analysis of ketamine -- 5. Brain imaging of ketamine abusers -- 6.Management of complications of ketamine abuse -- 7.Action site of ketamine in the NMDA receptor channel -- 8.Synaptic modulation in the effect of ketamine -- 9.Rodents whole-brain imaging in the effects of ketamine -- 10. Behavioral pharmacology of ketamine: An overview of preclinical studies -- 11.Antidepressant potential of ketamine enantiomers -- 12.Effects of ketamine on pain-related depression -- 13.Role of gut microbiota in the antidepressant actions of ketamine and its enantiomers -- 14. The role of NMDA receptor GluN2D subunit in the effects of ketamine and enantiomers -- 15.Roles of the lateral habenula in the actions of ketamine -- 16.Comparison of antidepressant action of ketamine and group II mGlu receptor antagonists -- 17.Antidepressant effects of ketamine in Taiwanese patients with treatment-resistant depression.

This book presents the latest data from basic research and clinical trials supporting the effectiveness of ketamine as a treatment for depression, bipolar disorder, and suicidal behavior, setting these positive findings within the context of the serious problem of ketamine abuse. The first part of the book focuses on the evidence regarding ketamine abuse, with specific reference to Asian countries, and discusses countermeasures and complication management. It then addresses the mechanisms underlying the antidepressant and side effects of ketamine, which have remained elusive, describing and discussing important new research findings. Further, it explains insights gained from whole brain imaging in rodents and from behavioral pharmacology, and presents evidence regarding the role of gut microbiota, the NMDA receptor GluN2D subunit, and the lateral habenula in the actions of ketamine. These advances form the basis for the safer use of ketamine in patients with treatment-resistant depression and are expected to lead to the development of new antidepressants. .

ISBN: 9789811529023

Standard No.: 10.1007/978-981-15-2902-3doiSubjects--Topical Terms:

593561
Neurosciences.

LC Class. No.: RC321-580

Dewey Class. No.: 612.8

Ketamine = From Abused Drug to Rapid-Acting Antidepressant /
LDR:03503nam a22003975i 4500 001 1019592
003 DE-He213
005 20200701004633.0
007 cr nn 008mamaa
008 210318s2020 si | s |||| 0|eng d
020 $a 9789811529023 $9 978-981-15-2902-3
024 7 $a 10.1007/978-981-15-2902-3 $2 doi
035 $a 978-981-15-2902-3
050 4 $a RC321-580
072 7 $a PSAN $2 bicssc
072 7 $a MED057000 $2 bisacsh
072 7 $a PSAN $2 thema
082 0 4 $a 612.8 $2 23
245 1 0 $a Ketamine $h [electronic resource] : $b From Abused Drug to Rapid-Acting Antidepressant / $c edited by Kenji Hashimoto, Soichiro Ide, Kazutaka Ikeda.
250 $a 1st ed. 2020.
264 1 $a Singapore : $b Springer Singapore : $b Imprint: Springer, $c 2020.
300 $a V, 189 p. 27 illus., 13 illus. in color. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
505 0 $a 1.Determination of ketamine in the river of China -- 2.Ketamine abuse in Taiwan -- 3.Ketamine problem in Hong Kong -- 4. Hair analysis of ketamine -- 5. Brain imaging of ketamine abusers -- 6.Management of complications of ketamine abuse -- 7.Action site of ketamine in the NMDA receptor channel -- 8.Synaptic modulation in the effect of ketamine -- 9.Rodents whole-brain imaging in the effects of ketamine -- 10. Behavioral pharmacology of ketamine: An overview of preclinical studies -- 11.Antidepressant potential of ketamine enantiomers -- 12.Effects of ketamine on pain-related depression -- 13.Role of gut microbiota in the antidepressant actions of ketamine and its enantiomers -- 14. The role of NMDA receptor GluN2D subunit in the effects of ketamine and enantiomers -- 15.Roles of the lateral habenula in the actions of ketamine -- 16.Comparison of antidepressant action of ketamine and group II mGlu receptor antagonists -- 17.Antidepressant effects of ketamine in Taiwanese patients with treatment-resistant depression.
520 $a This book presents the latest data from basic research and clinical trials supporting the effectiveness of ketamine as a treatment for depression, bipolar disorder, and suicidal behavior, setting these positive findings within the context of the serious problem of ketamine abuse. The first part of the book focuses on the evidence regarding ketamine abuse, with specific reference to Asian countries, and discusses countermeasures and complication management. It then addresses the mechanisms underlying the antidepressant and side effects of ketamine, which have remained elusive, describing and discussing important new research findings. Further, it explains insights gained from whole brain imaging in rodents and from behavioral pharmacology, and presents evidence regarding the role of gut microbiota, the NMDA receptor GluN2D subunit, and the lateral habenula in the actions of ketamine. These advances form the basis for the safer use of ketamine in patients with treatment-resistant depression and are expected to lead to the development of new antidepressants. .
650 0 $a Neurosciences. $3 593561
650 0 $a Pharmacology. $3 583819
650 0 $a Laboratory medicine. $3 1254567
650 0 $a Neurobiology. $3 573189
650 0 $a Neuropsychology. $3 556286
650 0 $a Neurology . $3 1253459
650 2 4 $a Pharmacology/Toxicology. $3 593882
650 2 4 $a Laboratory Medicine. $3 673604
650 2 4 $a Neurology. $3 593894
700 1 $a Hashimoto, Kenji. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1251028
700 1 $a Ide, Soichiro. $e editor. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1314901
700 1 $a Ikeda, Kazutaka. $e editor. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1314902
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9789811529016
776 0 8 $i Printed edition: $z 9789811529030
776 0 8 $i Printed edition: $z 9789811529047
856 4 0 $u https://doi.org/10.1007/978-981-15-2902-3
912 $a ZDB-2-SBL
912 $a ZDB-2-SXB
950 $a Biomedical and Life Sciences (SpringerNature-11642)
950 $a Biomedical and Life Sciences (R0) (SpringerNature-43708)