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Tumor Angiogenesis = A Key Target fo...
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Marmé, Dieter.
Tumor Angiogenesis = A Key Target for Cancer Therapy /
紀錄類型:
書目-語言資料,印刷品 : Monograph/item
正題名/作者:
Tumor Angiogenesis/ edited by Dieter Marmé.
其他題名:
A Key Target for Cancer Therapy /
其他作者:
Marmé, Dieter.
面頁冊數:
online resource. :
Contained By:
Springer Nature Living Reference
標題:
Oncology . -
電子資源:
https://doi.org/10.1007/978-3-319-31215-6
ISBN:
9783319312156
Tumor Angiogenesis = A Key Target for Cancer Therapy /
Tumor Angiogenesis
A Key Target for Cancer Therapy /[electronic resource] :edited by Dieter Marmé. - online resource.
Understanding of the molecular mechanisms of tumor development has increased considerably in recent years. As a consequence, the development of targeted therapies has proceeded rapidly, contributing to new drugs against cancer which are now under clinical investigation. Among these new therapies, anti-angiogenic drugs are of particular importance because they can be used against many different types of cancer. This is due to the fact that tumor angiogenesis seems to be involved in most if not all solid metastasizing malignancies. The first part of this book summarizes the knowledge acquired on the molecular entities that play a role in tumor angiogenesis and their mechanisms of action. Furthermore, the identification of molecular markers and their validation as predictive and/or prognostic tools is reviewed. In the second and most important part, the clinical applications of anti-angiogenic treatments are documented for a wide variety of tumors. In particular, the modes of combination with other targeted and/or cytotoxic cancer therapies are presented.
ISBN: 9783319312156
Standard No.: 10.1007/978-3-319-31215-6doiSubjects--Topical Terms:
1253469
Oncology .
LC Class. No.: RC254-282
Dewey Class. No.: 616.994
Tumor Angiogenesis = A Key Target for Cancer Therapy /
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Understanding of the molecular mechanisms of tumor development has increased considerably in recent years. As a consequence, the development of targeted therapies has proceeded rapidly, contributing to new drugs against cancer which are now under clinical investigation. Among these new therapies, anti-angiogenic drugs are of particular importance because they can be used against many different types of cancer. This is due to the fact that tumor angiogenesis seems to be involved in most if not all solid metastasizing malignancies. The first part of this book summarizes the knowledge acquired on the molecular entities that play a role in tumor angiogenesis and their mechanisms of action. Furthermore, the identification of molecular markers and their validation as predictive and/or prognostic tools is reviewed. In the second and most important part, the clinical applications of anti-angiogenic treatments are documented for a wide variety of tumors. In particular, the modes of combination with other targeted and/or cytotoxic cancer therapies are presented.
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