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Current Immunotherapeutic Strategies in Cancer

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Current Immunotherapeutic Strategies in Cancer/ edited by Matthias Theobald.
其他作者:	Theobald, Matthias.
面頁冊數:	V, 187 p.online resource. :
Contained By:	Springer Nature eBook
標題:	Oncology. -
電子資源:	https://doi.org/10.1007/978-3-030-23765-3
ISBN:	9783030237653

Current Immunotherapeutic Strategies in Cancer
Current Immunotherapeutic Strategies in Cancer[electronic resource] /edited by Matthias Theobald. - 1st ed. 2020. - V, 187 p.online resource. - Recent Results in Cancer Research,2140080-0015 ;. - Recent Results in Cancer Research,200.

Current Development of Monoclonal Antibodies in Cancer Therapy -- Clinical Experience with Bispecific T-Cell Engagers -- Advances and challenges of CAR-modified T cells in clinical trials -- Targeting Cancer with Genetically Engineered TCR-T Cells -- Tailored Vaccines Based on Patient’s Cancer Mutanome -- Next-Generation Checkpoint Inhibitors and Immune Agonists.

This book offers a comprehensive review of recent advances in cancer immunotherapy, and explores the value and limitations of the most effective current therapeutic strategies and emerging treatment modalities. It discusses in detail the successes achieved using monoclonal antibodies (mAbs), including developments with regard to conjugated mAbs and also bispecific mAbs as novel treatment options for leukemia and solid tumors. It also examines the advances toward personalized immunotherapy, focusing on the effectiveness of adoptive cell therapy using genetically engineered T cells with tumor-associated antigen-specific T-cell receptors and chimeric antigen receptors, as well as the role of tailored vaccines based on the patient’s cancer mutanome. Further, it describes the impressive therapeutic results recently achieved with checkpoint inhibitors, and analyzes novel strategies to modulate the immunosuppressive tumor microenvironment. Written by leading international experts and providing up-to-date information on emerging strategies, such as oncolytic virus-based therapy, epigenetic therapy, and combination therapy, the book appeals to all those with an interest in immunotherapy as it comes of age.

ISBN: 9783030237653

Standard No.: 10.1007/978-3-030-23765-3doiSubjects--Topical Terms:

593951
Oncology.

LC Class. No.: RC254-282

Dewey Class. No.: 616.994

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