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Central Nervous System Metastases

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Central Nervous System Metastases/ edited by Manmeet Ahluwalia, Philippe Metellus, Riccardo Soffietti.
其他作者:	Ahluwalia, Manmeet.
面頁冊數:	XIII, 421 p. 45 illus., 37 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Neurosurgery. -
電子資源:	https://doi.org/10.1007/978-3-030-23417-1
ISBN:	9783030234171

Central Nervous System Metastases
Central Nervous System Metastases[electronic resource] /edited by Manmeet Ahluwalia, Philippe Metellus, Riccardo Soffietti. - 1st ed. 2020. - XIII, 421 p. 45 illus., 37 illus. in color.online resource.

PREFACE -- I Epidemiology -- II Pathology and Biology -- 1 Pathology of brain metastases -- 2 Translationnal approaches -- 3 Molecular mechanisms driving brain metastases development -- 4 Genomics characterization of BM -- 5 BM cell partners and tumor microenvironment -- 6 Experimental models of Brain Metastases -- III Clinical presentation and symptom management -- 7 Clinical presentation -- 8 Epilepsy in CNS metastases -- 9 Safety, tolerability and use of steroids in CNS metastasis patients -- 10 Thrombo-embolic complications in BM patients -- IV Imaging -- 11 BM diagnosis and monitoring -- 12 Metabolic imaging of BM -- 13 Radiation necrosis and progression assessment and definition -- V Surgery -- 14 Modern surgical techniques -- 15 Quality of surgical resection assessment -- 16 Indications and emerging concepts in the era molecular biology -- VI Radiation Therapy -- 17 Stereotatic radiosurgery -- 18 WBRT -- 19 Combined radiation therapy and systemic treatment -- VII Systemic treatment -- 20 Lung -- 21 Breast.-. 22 Melanoma -- 23 Miscellaneous -- VIII Neurocognition and QoL -- IV Leptomeningeal disease -- X Prevention/Prohylaxis strategies -- XI Prognosis and prognostic models -- XII Clinical trials / Endpoints and outcome assessment. .

This book provides a comprehensive overview of brain metastases, from the molecular biology aspects to therapeutic management and perspectives. Due to the increasing incidence of these tumors and the urgent need to effectively control brain metastatic diseases in these patients, new therapeutic strategies have emerged in recent years. The volume discusses all these innovative approaches combined with new surgical techniques (fluorescence, functional mapping, integrated navigation), novel radiation therapy techniques (stereotactic radiosurgery) and new systemic treatment approaches such as targeted- and immunotherapy. These combination strategies represent a new therapeutic model in brain metastatic patients in which each medical practitioner (neurosurgeon, neurologist, medical oncologist, radiation oncologist) plays a pivotal role in defining the optimal treatment in a multidisciplinary approach. Written by recognized experts in the field, this book is a valuable tool for neurosurgeons, neuro-oncologists, neuroradiologists, medical oncologists, radiation oncologists, cognitive therapists, basic scientists and students working in the area of brain tumors.

ISBN: 9783030234171

Standard No.: 10.1007/978-3-030-23417-1doiSubjects--Topical Terms:

673771
Neurosurgery.

LC Class. No.: RD592.5-596

Dewey Class. No.: 617.48

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505 0 $a PREFACE -- I Epidemiology -- II Pathology and Biology -- 1 Pathology of brain metastases -- 2 Translationnal approaches -- 3 Molecular mechanisms driving brain metastases development -- 4 Genomics characterization of BM -- 5 BM cell partners and tumor microenvironment -- 6 Experimental models of Brain Metastases -- III Clinical presentation and symptom management -- 7 Clinical presentation -- 8 Epilepsy in CNS metastases -- 9 Safety, tolerability and use of steroids in CNS metastasis patients -- 10 Thrombo-embolic complications in BM patients -- IV Imaging -- 11 BM diagnosis and monitoring -- 12 Metabolic imaging of BM -- 13 Radiation necrosis and progression assessment and definition -- V Surgery -- 14 Modern surgical techniques -- 15 Quality of surgical resection assessment -- 16 Indications and emerging concepts in the era molecular biology -- VI Radiation Therapy -- 17 Stereotatic radiosurgery -- 18 WBRT -- 19 Combined radiation therapy and systemic treatment -- VII Systemic treatment -- 20 Lung -- 21 Breast.-. 22 Melanoma -- 23 Miscellaneous -- VIII Neurocognition and QoL -- IV Leptomeningeal disease -- X Prevention/Prohylaxis strategies -- XI Prognosis and prognostic models -- XII Clinical trials / Endpoints and outcome assessment. .
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