國立虎尾科技大學 |

Biochemistry for Anesthesiologists and Intensivists

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Biochemistry for Anesthesiologists and Intensivists/ edited by Fernando Alemanno.
other author:	Alemanno, Fernando.
Description:	XIV, 250 p. 65 illus., 22 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Anesthesiology. -
Online resource:	https://doi.org/10.1007/978-3-030-26721-6
ISBN:	9783030267216

Biochemistry for Anesthesiologists and Intensivists
Biochemistry for Anesthesiologists and Intensivists[electronic resource] /edited by Fernando Alemanno. - 1st ed. 2020. - XIV, 250 p. 65 illus., 22 illus. in color.online resource.

Foreword -- Preface -- Chapter 1 Enzymes and Coenzymes -- Chapter 2 Anaerobic Glycolysis or Embden-Meyerhof Pathway -- Chapter 3 The Tricarboxylic Acids Cycle or Krebs Cycle -- Chapter 4 The Collateral Glutamate – GABA Cycle -- Chapter 5 The Pentose Cycle or Direct Oxidative Pathway (DOP) (The Sleep Pathway) -- Chapter 6 Neurotransmitters -- Chapter 7 The Blood-Brain Barrier (BBB) -- Chapter 8 Shock -- Chapter 9 Cerebral Edema -- Chapter 10 The Pulmonary Surfactant -- Chapter 11 When the Mind Does Not Work As It Should -- Chapter 12 Thiamine (Vitamin B1) -- Chapter 13 Normobaric Oxygen Therapy (NBO) -- Chapter 14 The Acid – Base equilibrium -- Chapter 15 Theories of Narcosis -- Chapter 16 Local Anaesthetics -- Chapter 17 Perineural Adjuvants -- Chapter 18 The Grand Design -- Chapter 19 Epilogue and Farewell.

This book discusses and explains the importance of biochemistry knowledge in understanding what happens to patients during anesthesia and/or to those being in intensive care. It covers a wide range of topics, such as Cerebral Edema, Shock, Blood-Brain Barrier, The Pulmonary surfactant, The Acid – Base equilibrium, Local anaesthetics, Perineural adjuvants, Normobaric Oxygen Therapy, Theories of Narcosis. Hyperventilation effects and consequences are also presented. For instance, by hyperventilating a patient with a PaCO2 significantly below 25 mmHg, we risk blocking pyruvic acid carboxylation and transforming it into oxalacetic acid, which in turn knocks out the Krebs cycle, possibly leading to a complication, i.e. to metabolic acidosis and not to compensation for respiratory alkalosis. It is also worth remembering that vitamins are actually molecules of pretty considerable potency and should not be simply intended as integrators. If we inject a patient under intensive care with vitamin C, this not only plays a capillary-protective role but facilitates the conversion of dopamine to noradrenaline. As far as vitamin B6 goes, not only is it the most natural of antiemetics but the coenzyme responsible for transforming glutamate as one of the most powerful excitatory mediators into GABA, one of the fiercest inhibitors. Anesthesiological and intensive care practice require a detailed biochemistry knowledge to avoid onset of complications and/or to deal with unexpected events promptly and appropriately. The book is intended for anesthesiologists, intensivists, anesthesia teachers, anesthesia trainees and residents.

ISBN: 9783030267216

Standard No.: 10.1007/978-3-030-26721-6doiSubjects--Topical Terms:

645681
Anesthesiology.

LC Class. No.: RD78.3-87.3

Dewey Class. No.: 617.96

Biochemistry for Anesthesiologists and Intensivists
LDR:03794nam a22003975i 4500 001 1027067
003 DE-He213
005 20200703103001.0
007 cr nn 008mamaa
008 210318s2020 gw | s |||| 0|eng d
020 $a 9783030267216 $9 978-3-030-26721-6
024 7 $a 10.1007/978-3-030-26721-6 $2 doi
035 $a 978-3-030-26721-6
050 4 $a RD78.3-87.3
072 7 $a MMB $2 bicssc
072 7 $a MED006000 $2 bisacsh
072 7 $a MKA $2 thema
082 0 4 $a 617.96 $2 23
245 1 0 $a Biochemistry for Anesthesiologists and Intensivists $h [electronic resource] / $c edited by Fernando Alemanno.
250 $a 1st ed. 2020.
264 1 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2020.
300 $a XIV, 250 p. 65 illus., 22 illus. in color. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
505 0 $a Foreword -- Preface -- Chapter 1 Enzymes and Coenzymes -- Chapter 2 Anaerobic Glycolysis or Embden-Meyerhof Pathway -- Chapter 3 The Tricarboxylic Acids Cycle or Krebs Cycle -- Chapter 4 The Collateral Glutamate – GABA Cycle -- Chapter 5 The Pentose Cycle or Direct Oxidative Pathway (DOP) (The Sleep Pathway) -- Chapter 6 Neurotransmitters -- Chapter 7 The Blood-Brain Barrier (BBB) -- Chapter 8 Shock -- Chapter 9 Cerebral Edema -- Chapter 10 The Pulmonary Surfactant -- Chapter 11 When the Mind Does Not Work As It Should -- Chapter 12 Thiamine (Vitamin B1) -- Chapter 13 Normobaric Oxygen Therapy (NBO) -- Chapter 14 The Acid – Base equilibrium -- Chapter 15 Theories of Narcosis -- Chapter 16 Local Anaesthetics -- Chapter 17 Perineural Adjuvants -- Chapter 18 The Grand Design -- Chapter 19 Epilogue and Farewell.
520 $a This book discusses and explains the importance of biochemistry knowledge in understanding what happens to patients during anesthesia and/or to those being in intensive care. It covers a wide range of topics, such as Cerebral Edema, Shock, Blood-Brain Barrier, The Pulmonary surfactant, The Acid – Base equilibrium, Local anaesthetics, Perineural adjuvants, Normobaric Oxygen Therapy, Theories of Narcosis. Hyperventilation effects and consequences are also presented. For instance, by hyperventilating a patient with a PaCO2 significantly below 25 mmHg, we risk blocking pyruvic acid carboxylation and transforming it into oxalacetic acid, which in turn knocks out the Krebs cycle, possibly leading to a complication, i.e. to metabolic acidosis and not to compensation for respiratory alkalosis. It is also worth remembering that vitamins are actually molecules of pretty considerable potency and should not be simply intended as integrators. If we inject a patient under intensive care with vitamin C, this not only plays a capillary-protective role but facilitates the conversion of dopamine to noradrenaline. As far as vitamin B6 goes, not only is it the most natural of antiemetics but the coenzyme responsible for transforming glutamate as one of the most powerful excitatory mediators into GABA, one of the fiercest inhibitors. Anesthesiological and intensive care practice require a detailed biochemistry knowledge to avoid onset of complications and/or to deal with unexpected events promptly and appropriately. The book is intended for anesthesiologists, intensivists, anesthesia teachers, anesthesia trainees and residents.
650 0 $a Anesthesiology. $3 645681
650 0 $a Critical care medicine. $3 644413
650 0 $a Pain medicine. $3 790323
650 2 4 $a Intensive / Critical Care Medicine. $3 673790
650 2 4 $a Pain Medicine. $3 669117
700 1 $a Alemanno, Fernando. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1022745
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9783030267209
776 0 8 $i Printed edition: $z 9783030267223
776 0 8 $i Printed edition: $z 9783030267230
856 4 0 $u https://doi.org/10.1007/978-3-030-26721-6
912 $a ZDB-2-SME
912 $a ZDB-2-SXM
950 $a Medicine (SpringerNature-11650)
950 $a Medicine (R0) (SpringerNature-43714)