國立虎尾科技大學 |

Selected Reaction Monitoring Mass Spectrometry (SRM-MS) in Proteomics = A Comprehensive View /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Selected Reaction Monitoring Mass Spectrometry (SRM-MS) in Proteomics/ by Mahmud Hossain.
其他題名:	A Comprehensive View /
作者:	Hossain, Mahmud.
面頁冊數:	XVII, 283 p. 102 illus., 86 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Computer Applications in Chemistry. -
電子資源:	https://doi.org/10.1007/978-3-030-53433-2
ISBN:	9783030534332

Selected Reaction Monitoring Mass Spectrometry (SRM-MS) in Proteomics = A Comprehensive View /
Hossain, Mahmud.

Selected Reaction Monitoring Mass Spectrometry (SRM-MS) in ProteomicsA Comprehensive View /[electronic resource] :by Mahmud Hossain. - 1st ed. 2020. - XVII, 283 p. 102 illus., 86 illus. in color.online resource.

Chapter 1: Introduction -- Chapter 2: The mass spectrometer and its components -- Chapter 3: Selected reaction monitoring mass spectrometry (SRM-MS) -- Chapter 4: Development of SRM-MS experiment -- Chapter 5: Bioinformatics tools for SRM-MS -- Chapter 6: Quantification by SRM-MS -- Chapter 7: SRM-MS applications in proteomics -- Chapter 8: SRM-MS for posttranslational modification (PTM) analysis -- Chapter 9: Challenges, current trends and future directions -- Bibliography -- Index.

Covering a wide-ranging facet of a “gold-standard” targeted mass spectrometry (MS) method for the consistent detection and accurate quantification of preselected proteins in complex biological matrices, Selected Reaction Monitoring Mass Spectrometry (SRM-MS) in Proteomics: A Comprehensive View describes: The knowledge-based development of highly efficient SRM methodology including assay workflow, selection of proteins, peptides, transitions and its validation, and quality assessment Available bioinformatic tools – for both pre-acquisition method development and post-MS acquisition data analysis and data repositories Various relative and absolute quantification techniques SRM-MS’ widespread applications in biomarker development and in clinical studies, as well as in the analysis of various posttranslational modifications (PTMs) Current challenges and contemporary trends to overcome those difficulties In addition, it features the historical development of modern-day mass spectrometry with its vivid applications and also covers basic MS instrumentation, ionization techniques, and various proteomics approaches. Comprehensive discussion, extensive references at the end of each chapter, and the list of review articles in the bibliography offer invaluable resources for advanced readings. Researchers from the undergraduate to postgraduate level and beyond in both academic or industry settings studying and working on mass spectrometry and/or proteomics will benefit from this book.

ISBN: 9783030534332

Standard No.: 10.1007/978-3-030-53433-2doiSubjects--Topical Terms:

672434
Computer Applications in Chemistry.

LC Class. No.: QD431-431.7

Dewey Class. No.: 572.6

Selected Reaction Monitoring Mass Spectrometry (SRM-MS) in Proteomics = A Comprehensive View /
LDR:03402nam a22003975i 4500 001 1029714
003 DE-He213
005 20200926204727.0
007 cr nn 008mamaa
008 210318s2020 gw | s |||| 0|eng d
020 $a 9783030534332 $9 978-3-030-53433-2
024 7 $a 10.1007/978-3-030-53433-2 $2 doi
035 $a 978-3-030-53433-2
050 4 $a QD431-431.7
072 7 $a PSBC $2 bicssc
072 7 $a SCI007000 $2 bisacsh
072 7 $a PSB $2 thema
082 0 4 $a 572.6 $2 23
100 1 $a Hossain, Mahmud. $e author. $4 aut $4 http://id.loc.gov/vocabulary/relators/aut $3 1326521
245 1 0 $a Selected Reaction Monitoring Mass Spectrometry (SRM-MS) in Proteomics $h [electronic resource] : $b A Comprehensive View / $c by Mahmud Hossain.
250 $a 1st ed. 2020.
264 1 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2020.
300 $a XVII, 283 p. 102 illus., 86 illus. in color. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
505 0 $a Chapter 1: Introduction -- Chapter 2: The mass spectrometer and its components -- Chapter 3: Selected reaction monitoring mass spectrometry (SRM-MS) -- Chapter 4: Development of SRM-MS experiment -- Chapter 5: Bioinformatics tools for SRM-MS -- Chapter 6: Quantification by SRM-MS -- Chapter 7: SRM-MS applications in proteomics -- Chapter 8: SRM-MS for posttranslational modification (PTM) analysis -- Chapter 9: Challenges, current trends and future directions -- Bibliography -- Index.
520 $a Covering a wide-ranging facet of a “gold-standard” targeted mass spectrometry (MS) method for the consistent detection and accurate quantification of preselected proteins in complex biological matrices, Selected Reaction Monitoring Mass Spectrometry (SRM-MS) in Proteomics: A Comprehensive View describes: The knowledge-based development of highly efficient SRM methodology including assay workflow, selection of proteins, peptides, transitions and its validation, and quality assessment Available bioinformatic tools – for both pre-acquisition method development and post-MS acquisition data analysis and data repositories Various relative and absolute quantification techniques SRM-MS’ widespread applications in biomarker development and in clinical studies, as well as in the analysis of various posttranslational modifications (PTMs) Current challenges and contemporary trends to overcome those difficulties In addition, it features the historical development of modern-day mass spectrometry with its vivid applications and also covers basic MS instrumentation, ionization techniques, and various proteomics approaches. Comprehensive discussion, extensive references at the end of each chapter, and the list of review articles in the bibliography offer invaluable resources for advanced readings. Researchers from the undergraduate to postgraduate level and beyond in both academic or industry settings studying and working on mass spectrometry and/or proteomics will benefit from this book.
650 2 4 $a Computer Applications in Chemistry. $3 672434
650 2 4 $a Spectroscopy/Spectrometry. $3 782573
650 2 4 $a Mass Spectrometry. $3 782160
650 0 $a Chemoinformatics. $3 1256018
650 0 $a Spectroscopy. $3 1102161
650 0 $a Mass spectrometry. $3 583253
650 0 $a Proteomics. $3 581930
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9783030534325
776 0 8 $i Printed edition: $z 9783030534349
776 0 8 $i Printed edition: $z 9783030534356
856 4 0 $u https://doi.org/10.1007/978-3-030-53433-2
912 $a ZDB-2-SBL
912 $a ZDB-2-SXB
950 $a Biomedical and Life Sciences (SpringerNature-11642)
950 $a Biomedical and Life Sciences (R0) (SpringerNature-43708)