國立虎尾科技大學 |

Drug Targets in Cellular Processes of Cancer: From Nonclinical to Preclinical Models

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Drug Targets in Cellular Processes of Cancer: From Nonclinical to Preclinical Models/ edited by Hardeep Singh Tuli.
其他作者:	Tuli, Hardeep Singh.
面頁冊數:	XIII, 228 p. 28 illus., 26 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Cell Biology. -
電子資源:	https://doi.org/10.1007/978-981-15-7586-0
ISBN:	9789811575860

Drug Targets in Cellular Processes of Cancer: From Nonclinical to Preclinical Models
Drug Targets in Cellular Processes of Cancer: From Nonclinical to Preclinical Models[electronic resource] /edited by Hardeep Singh Tuli. - 1st ed. 2020. - XIII, 228 p. 28 illus., 26 illus. in color.online resource.

Chapter 1. History of oncotherapies in cancer biology -- Chapter 2. Electrochemical Sensors and Biosensors for the Detection of Cancer Biomarkers and Drugs -- Chapter 3. Cell cycle arrest: An impending therapeutic strategy to curb cancer -- Chapter 4. Apoptotic cell death: important cellular process as chemotherapeutic target -- Chapter 5. Regulatory roles of autophagy in cancer -- Chapter 6. ROS and Oxidative Stress in Cancer: Recent Advances -- Chapter 7. Inflammatory mediators: Potential drug targets in cancer -- Chapter 8. Pharmacologic modulation of the immune response against tumours in the elderly. Chapter 9. Angiogenesis: A Therapeutic Target for Cancer -- Chapter 10. Metastasis: A major driver of cancer pathogenesis -- Chapter 11. Designing Personalized and Innovative Novel Drug Therapies For Cancer Treatment.

This book explores potential cellular drug targets for cancer therapy. The first couple of chapters describe conventional treatment (radiotherapy, chemotherapy, and immunotherapy) & detection (biosensors) strategies for cancer. In contrast, the subsequent chapters address the role of cyclin-dependent kinases and cell cycle regulatory proteins in the growth of cancer cells and their potential as target for cancer treatment. The book then discusses the regulation of various pro-apoptotic and anti-apoptotic proteins via chemotherapeutic drugs. In addition, it examines the molecular mechanisms that are critical for mediating autophagic cell death in cancer cells. It subsequently reviews the role of reactive oxygen (ROS) species during carcinogenesis and during chemotherapy, and the potential of anti-inflammatory routes for the development of new therapeutic modulators. Lastly, it describes therapeutic strategies that target the tumor microenvironment and various angiogenic pathways for the treatment of cancer and to develop personalized medicine. Given its scope, the book is valuable resource for oncologists, cancer researchers, clinicians, and pharmaceutical industry personnel.

ISBN: 9789811575860

Standard No.: 10.1007/978-981-15-7586-0doiSubjects--Topical Terms:

593889
Cell Biology.

LC Class. No.: RC261-271

Dewey Class. No.: 614.5999

Drug Targets in Cellular Processes of Cancer: From Nonclinical to Preclinical Models
LDR:03425nam a22003975i 4500 001 1029942
003 DE-He213
005 20200930110915.0
007 cr nn 008mamaa
008 210318s2020 si | s |||| 0|eng d
020 $a 9789811575860 $9 978-981-15-7586-0
024 7 $a 10.1007/978-981-15-7586-0 $2 doi
035 $a 978-981-15-7586-0
050 4 $a RC261-271
072 7 $a MJCL $2 bicssc
072 7 $a MED062000 $2 bisacsh
072 7 $a MJCL $2 thema
082 0 4 $a 614.5999 $2 23
245 1 0 $a Drug Targets in Cellular Processes of Cancer: From Nonclinical to Preclinical Models $h [electronic resource] / $c edited by Hardeep Singh Tuli.
250 $a 1st ed. 2020.
264 1 $a Singapore : $b Springer Singapore : $b Imprint: Springer, $c 2020.
300 $a XIII, 228 p. 28 illus., 26 illus. in color. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
505 0 $a Chapter 1. History of oncotherapies in cancer biology -- Chapter 2. Electrochemical Sensors and Biosensors for the Detection of Cancer Biomarkers and Drugs -- Chapter 3. Cell cycle arrest: An impending therapeutic strategy to curb cancer -- Chapter 4. Apoptotic cell death: important cellular process as chemotherapeutic target -- Chapter 5. Regulatory roles of autophagy in cancer -- Chapter 6. ROS and Oxidative Stress in Cancer: Recent Advances -- Chapter 7. Inflammatory mediators: Potential drug targets in cancer -- Chapter 8. Pharmacologic modulation of the immune response against tumours in the elderly. Chapter 9. Angiogenesis: A Therapeutic Target for Cancer -- Chapter 10. Metastasis: A major driver of cancer pathogenesis -- Chapter 11. Designing Personalized and Innovative Novel Drug Therapies For Cancer Treatment.
520 $a This book explores potential cellular drug targets for cancer therapy. The first couple of chapters describe conventional treatment (radiotherapy, chemotherapy, and immunotherapy) & detection (biosensors) strategies for cancer. In contrast, the subsequent chapters address the role of cyclin-dependent kinases and cell cycle regulatory proteins in the growth of cancer cells and their potential as target for cancer treatment. The book then discusses the regulation of various pro-apoptotic and anti-apoptotic proteins via chemotherapeutic drugs. In addition, it examines the molecular mechanisms that are critical for mediating autophagic cell death in cancer cells. It subsequently reviews the role of reactive oxygen (ROS) species during carcinogenesis and during chemotherapy, and the potential of anti-inflammatory routes for the development of new therapeutic modulators. Lastly, it describes therapeutic strategies that target the tumor microenvironment and various angiogenic pathways for the treatment of cancer and to develop personalized medicine. Given its scope, the book is valuable resource for oncologists, cancer researchers, clinicians, and pharmaceutical industry personnel.
650 2 4 $a Cell Biology. $3 593889
650 1 4 $a Cancer Research. $3 668358
650 0 $a Cell biology. $3 1253486
650 0 $a Immunology. $3 592892
650 0 $a Cancer research. $3 1253664
700 1 $a Tuli, Hardeep Singh. $e editor. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1326764
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9789811575853
776 0 8 $i Printed edition: $z 9789811575877
776 0 8 $i Printed edition: $z 9789811575884
856 4 0 $u https://doi.org/10.1007/978-981-15-7586-0
912 $a ZDB-2-SBL
912 $a ZDB-2-SXB
950 $a Biomedical and Life Sciences (SpringerNature-11642)
950 $a Biomedical and Life Sciences (R0) (SpringerNature-43708)