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Tumor vascularization
~
Pezzella, Francesco.
Tumor vascularization
紀錄類型:
書目-語言資料,印刷品 : Monograph/item
正題名/作者:
Tumor vascularization/ edited by Domenico Ribatti and Francesco Pezzella.
其他作者:
Pezzella, Francesco.
出版者:
London :Academic Press, : 2020.,
面頁冊數:
1 online resource (200 p.)
附註:
Long noncoding RNAs pathway
標題:
Tumors - Blood-vessels. -
電子資源:
https://www.sciencedirect.com/science/book/9780128194942
ISBN:
9780128220276
Tumor vascularization
Tumor vascularization
[electronic resource] /edited by Domenico Ribatti and Francesco Pezzella. - London :Academic Press,2020. - 1 online resource (200 p.)
Long noncoding RNAs pathway
Front Cover -- Tumor Vascularization -- Copyright Page -- Contents -- List of contributors -- Preface -- 1 Sprouting and nonsprouting angiogenesis in tumors -- Introduction -- The angiogenic switch -- Sprouting tumor angiogenesis -- Intussusceptive microvascular growth angiogenesis -- Glomeruloid vascular proliferation -- Concluding remarks -- References -- 2 Nonangiogenic tumor growth -- Introduction -- Identification of nonangiogenic tumors -- Alveolar growth pattern -- Lepidic growth pattern -- Interstitial growth pattern -- Perivascular (cuffing) growth pattern
ISBN: 9780128220276Subjects--Topical Terms:
678322
Tumors
--Blood-vessels.Index Terms--Genre/Form:
554714
Electronic books.
LC Class. No.: RC269
Dewey Class. No.: 616.99/407
Tumor vascularization
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Front Cover -- Tumor Vascularization -- Copyright Page -- Contents -- List of contributors -- Preface -- 1 Sprouting and nonsprouting angiogenesis in tumors -- Introduction -- The angiogenic switch -- Sprouting tumor angiogenesis -- Intussusceptive microvascular growth angiogenesis -- Glomeruloid vascular proliferation -- Concluding remarks -- References -- 2 Nonangiogenic tumor growth -- Introduction -- Identification of nonangiogenic tumors -- Alveolar growth pattern -- Lepidic growth pattern -- Interstitial growth pattern -- Perivascular (cuffing) growth pattern
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The biology of nonangiogenic growth -- Hypoxia and angiogenesis -- Inflammation and immune response -- Motility, invasion, and cell-cell adhesion -- Energy metabolism -- What causes tumors to grow in an angiogenic or nonangiogenic, vessel co-opting way? -- Blood vessels change when they are co-opted by malignant cells -- Conclusion -- References -- 3 Vascular co-option -- Vascular co-option in normal and transformed cells -- Vascular co-option in non-cancer cells -- Vascular co-option in cancer cells -- Molecular regulation of vascular co-option
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Molecular regulation of cell adhesion and proliferation in vascular co-option -- Molecular regulation of migration and invasion linked to vascular co-option -- Molecular regulation of dormancy, latency, and awakening linked to vascular co-option -- Preclinical applications to target vascular co-option: prevention of metastasis -- Acknowledgments -- References -- 4 Pericyte mimicry: an embryogenesis-derived program of extravascular tumor cell migration -- Introduction -- Interactions between tumor cells and blood vessels -- History -- Angiotropism, PM and EVMM -- PM in melanoma -- Histopathology
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Histological criteria -- Melanoma liver metastases -- Experimental models of PM -- Prognostic significance of angiotropism and PM -- Molecular findings -- Angiotropism, PM, and EVMM in non-melanoma tumors -- Molecular studies -- Laminin and cancer cell migration -- Laminins in melanoma -- Laminins in non-melanoma tumors -- Modulation of laminins in embryogenesis and in cancer progression -- PM and EVMM: Reversion to an embryogenesis-derived program -- Analogies between embryogenesis and cancer development -- Neural crest cell migration: a model for PM/EVMM -- Angiogenesis -- Cell competition
505
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PM and EVMM: routes, direction and timing according to an embryogenesis-derived program -- Space, direction, and timing -- Perspectives and therapeutic implications -- Detection of PM and EVMM -- Therapeutic perspectives -- DAN -- YAP signaling -- Laminins -- Concluding remarks -- PM and vascular co-option: complementary embryonic phenomena? -- Acknowledgments -- References -- 5 Vasculogenic mimicry -- Introduction -- Vasculogenic mimicry in prognosis and progress -- Molecular pathway of vasculogenic mimicry -- Hypoxia/hypoxia-inducible factor pathway -- Vascular endothelial-cadherin pathway
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https://www.sciencedirect.com/science/book/9780128194942
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