國立虎尾科技大學 |

Middle Molecular Strategy = Flow Synthesis to Functional Molecules /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Middle Molecular Strategy/ edited by Koichi Fukase, Takayuki Doi.
其他題名:	Flow Synthesis to Functional Molecules /
其他作者:	Doi, Takayuki.
面頁冊數:	X, 357 p. 281 illus., 101 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Pharmaceutical Sciences/Technology. -
電子資源:	https://doi.org/10.1007/978-981-16-2458-2
ISBN:	9789811624582

Middle Molecular Strategy = Flow Synthesis to Functional Molecules /
Middle Molecular StrategyFlow Synthesis to Functional Molecules /[electronic resource] :edited by Koichi Fukase, Takayuki Doi. - 1st ed. 2021. - X, 357 p. 281 illus., 101 illus. in color.online resource.

Part I: Development of bio-functional middle molecules -- 1. Introduction -- 2. Total Synthesis, Biological Evaluation and 3D Structural Analysis of Cyclodepsipeptide Natural Products -- 3. Development of the Middle-size Molecules for Alkylation to Higher-Order Structures of Nucleic Acids -- 4. In Situ Synthesis of Glycoconjugates on Cell Surface: Selective Cell Imaging Using Low-Affinity Glycan Ligands -- 5. Assembled mid-sized agents that control intracellular protein-protein interactions -- 6. Macrocyclic mid-sized peptides with new chemical modalities -- Part II: Achievement of highly efficient synthesis of bioactive middle molecules -- 7. Enantioselective Total Synthesis of Cotylenin -- 8. Flow Chemistry for the Construction of Polycyclic Skeleton -- 9. Electrochemical Synthesis of Oligosaccharides as Middle-sized Molecules -- 10. Efficient Synthesis of Biologically Active Peptides based on Micro-flow Amide Bond Formation -- 11. Design and Concise De Novo Synthesis of Artemisinin Analogs.

This book highlights recently discovered aspects of “middle-size molecules,” focusing on (1) their unique bio-functions on the basis of derivatives and conjugates of natural products, saccharides, peptides, and nucleotides; (2) the synthesis of structurally complex natural products; (3) special synthetic methods for π-conjugated functional molecules; and (4) novel synthetic methods using flow chemistry. Given its scope, the book is of interest to industrial researchers and graduate students in the fields of organic chemistry, medicinal chemistry, and materials science. .

ISBN: 9789811624582

Standard No.: 10.1007/978-981-16-2458-2doiSubjects--Topical Terms:

768561
Pharmaceutical Sciences/Technology.

LC Class. No.: QD241-441

Dewey Class. No.: 547

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