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Non-coding RNAs at the Cross-Road of Cardiometabolic Diseases and Cancer

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Non-coding RNAs at the Cross-Road of Cardiometabolic Diseases and Cancer / by Paul Holvoet.
Author:	Holvoet, Paul.
Description:	XXX, 265 p. 26 illus., 24 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Human genetics. -
Online resource:	https://doi.org/10.1007/978-3-030-68844-8
ISBN:	9783030688448

Non-coding RNAs at the Cross-Road of Cardiometabolic Diseases and Cancer
Holvoet, Paul.

Non-coding RNAs at the Cross-Road of Cardiometabolic Diseases and Cancer [electronic resource] /by Paul Holvoet. - 1st ed. 2021. - XXX, 265 p. 26 illus., 24 illus. in color.online resource.

Biogenesis and Modes of Action Of miRs And Circular And Long Non-coding RNAs -- Obesity, Insulin Resistance in Adipose Tissue And Thermogenesis -- Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease -- Atherosclerosis -- Cardiomyopathy and Heart Failure -- Cancer -- Communication between Tumor-Adjacent Tissues and Tumors with Emphasis on Role of Inflammatory Cells -- General Conclusions and Future Perspectives.

This book gives insight into the functional role of non-coding RNAs in central pathways contributing to the development of obesity, type 2 diabetes, non-alcoholic fatty liver disease, atherosclerosis, myocardial infarction, cardiomyopathy, and heart failure. It also sheds light on the relationship of this cluster with cancer. Tumor cells, in contrast to cells in cardiometabolic tissues, can regulate this cluster of non-coding RNAs to escape from oxidative stress and anti-tumor immunity and maintain insulin sensitivity, facilitating cancer progression. The book presents a cluster of non-coding RNAs that may be prospectively analyzed in extensive cohort studies to determine their value in risk-predicting machine learning algorithms. In addition, it emphasizes the role of microvesicles in communication between tumor-adjacent tissue, inflammatory cells, and tumor cells, with a special focus on the role of miR-155. The book intends to promote interdisciplinary research. Due to the comprehensive background information provided in each chapter, it is suitable for researchers in academia and industry and for graduate students in biology, bioengineering, and medicine. .

ISBN: 9783030688448

Standard No.: 10.1007/978-3-030-68844-8doiSubjects--Topical Terms:

596505
Human genetics.

LC Class. No.: RB155-155.8

Dewey Class. No.: 611.01816

Non-coding RNAs at the Cross-Road of Cardiometabolic Diseases and Cancer
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520 $a This book gives insight into the functional role of non-coding RNAs in central pathways contributing to the development of obesity, type 2 diabetes, non-alcoholic fatty liver disease, atherosclerosis, myocardial infarction, cardiomyopathy, and heart failure. It also sheds light on the relationship of this cluster with cancer. Tumor cells, in contrast to cells in cardiometabolic tissues, can regulate this cluster of non-coding RNAs to escape from oxidative stress and anti-tumor immunity and maintain insulin sensitivity, facilitating cancer progression. The book presents a cluster of non-coding RNAs that may be prospectively analyzed in extensive cohort studies to determine their value in risk-predicting machine learning algorithms. In addition, it emphasizes the role of microvesicles in communication between tumor-adjacent tissue, inflammatory cells, and tumor cells, with a special focus on the role of miR-155. The book intends to promote interdisciplinary research. Due to the comprehensive background information provided in each chapter, it is suitable for researchers in academia and industry and for graduate students in biology, bioengineering, and medicine. .
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