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Introduction to Antibody Engineering

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Introduction to Antibody Engineering/ edited by Florian Rüker, Gordana Wozniak-Knopp.
其他作者:	Wozniak-Knopp, Gordana.
面頁冊數:	VIII, 388 p. 69 illus., 52 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Protein-Ligand Interactions. -
電子資源:	https://doi.org/10.1007/978-3-030-54630-4
ISBN:	9783030546304

Introduction to Antibody Engineering
Introduction to Antibody Engineering[electronic resource] /edited by Florian Rüker, Gordana Wozniak-Knopp. - 1st ed. 2021. - VIII, 388 p. 69 illus., 52 illus. in color.online resource. - Learning Materials in Biosciences,2509-6133. - Learning Materials in Biosciences,1.

Chapter 1. Introduction by the editors -- Chapter 2. Antibodies – A History of their Discovery and Properties -- Chapter 3. Monoclonal Antibodies and Hybridomas -- Chapter 4. Antibody Display Systems -- Chapter 5. Transgenic Animals for the Generation of Human Antibodies -- Chapter 6. Applications of Antibodies in Therapy, Diagnosis & Science -- Chapter 7. Bispecific antibodies -- Chapter 8. Antibody-Drug Conjugates -- Chapter 9. Alternative Binding Scaffolds – multipurpose binders for applications in basic research and therapy -- Chapter 10: Chimeric antigen receptor (CAR) redirected T cells -- Chapter 11. Improvement of Key Characteristics of Antibodies -- Chapter 12. Engineering therapeutic antibodies for development -- Chapter 13. Eukaryotic expression systems for upstream pro-cessing of monoclonal antibodies -- Chapter 14. Antibody Validation.

This highly readable textbook serves as a concise and engaging primer to the emerging field of antibody engineering and its various applications. It introduces readers to the basic science and molecular structure of antibodies, and explores how to characterize and engineer them. Readers will find an overview of the latest methods in antibody identification, improvement and biochemical engineering. Furthermore, alternative antibody formats and bispecific antibodies are discussed. The book’s content is based on lectures for the specializations “Protein Engineering” and “Medical Biotechnology” within the Master’s curriculum in “Biotechnology.” The lectures have been held at the University of Natural Resources and Life Sciences, Vienna, in cooperation with the Medical University of Vienna, since 2012 and are continuously adapted to reflect the latest developments in the field. The book addresses Master’s and PhD students in biotechnology, molecular biology and immunology, and all those who are interested in antibody engineering.

ISBN: 9783030546304

Standard No.: 10.1007/978-3-030-54630-4doiSubjects--Topical Terms:

882815
Protein-Ligand Interactions.

LC Class. No.: QR186.7-186.85

Dewey Class. No.: 616.0798

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