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Melanin Chemistry Explored by Quantu...
~
Kishida, Ryo.
Melanin Chemistry Explored by Quantum Mechanics = Investigations for Mechanism Identification and Reaction Design /
Record Type:
Language materials, printed : Monograph/item
Title/Author:
Melanin Chemistry Explored by Quantum Mechanics/ by Ryo Kishida, Susan Meñez Aspera, Hideaki Kasai.
Reminder of title:
Investigations for Mechanism Identification and Reaction Design /
Author:
Kishida, Ryo.
other author:
Kasai, Hideaki.
Description:
X, 83 p. 49 illus., 32 illus. in color.online resource. :
Contained By:
Springer Nature eBook
Subject:
Bioorganic Chemistry. -
Online resource:
https://doi.org/10.1007/978-981-16-1315-9
ISBN:
9789811613159
Melanin Chemistry Explored by Quantum Mechanics = Investigations for Mechanism Identification and Reaction Design /
Kishida, Ryo.
Melanin Chemistry Explored by Quantum Mechanics
Investigations for Mechanism Identification and Reaction Design /[electronic resource] :by Ryo Kishida, Susan Meñez Aspera, Hideaki Kasai. - 1st ed. 2021. - X, 83 p. 49 illus., 32 illus. in color.online resource.
1. Melanin Chemistry: A General Overview -- 2. Dopachrome Conversion: Mechanisms and Effects of Cu(II) Ion -- 3. Reactions Involving o-quinones: Cyclization and Binding of Thiols -- 4. Concluding Remarks and Future Perspectives.
This book discusses recent advances in theoretical–computational studies on the biosynthesis of melanin pigment (melanogenesis). These advances are being driven by the development of high-performance computers, new experimental findings, and extensive work on medical applications involving the control of pigmentation and the treatment of challenging dermatological diseases. Understanding the elementary processes involved in chemical reactions at the atomic scale is important in biochemical reaction design for effective control of the pigmentary system. Accordingly, the book focuses on the elementary steps involved in melanogenesis, which crucially affect the composition of the resulting melanin pigment by means of competitive reactions. The book also addresses reactions analogous to melanogenesis, with a focus on o-quinone reactions, which are especially important for understanding melanogenesis-associated cytotoxicity.
ISBN: 9789811613159
Standard No.: 10.1007/978-981-16-1315-9doiSubjects--Topical Terms:
677511
Bioorganic Chemistry.
LC Class. No.: QD450-801
Dewey Class. No.: 541.2
Melanin Chemistry Explored by Quantum Mechanics = Investigations for Mechanism Identification and Reaction Design /
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1. Melanin Chemistry: A General Overview -- 2. Dopachrome Conversion: Mechanisms and Effects of Cu(II) Ion -- 3. Reactions Involving o-quinones: Cyclization and Binding of Thiols -- 4. Concluding Remarks and Future Perspectives.
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This book discusses recent advances in theoretical–computational studies on the biosynthesis of melanin pigment (melanogenesis). These advances are being driven by the development of high-performance computers, new experimental findings, and extensive work on medical applications involving the control of pigmentation and the treatment of challenging dermatological diseases. Understanding the elementary processes involved in chemical reactions at the atomic scale is important in biochemical reaction design for effective control of the pigmentary system. Accordingly, the book focuses on the elementary steps involved in melanogenesis, which crucially affect the composition of the resulting melanin pigment by means of competitive reactions. The book also addresses reactions analogous to melanogenesis, with a focus on o-quinone reactions, which are especially important for understanding melanogenesis-associated cytotoxicity.
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