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Progress in the Chemistry of Organic Natural Products 115

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Progress in the Chemistry of Organic Natural Products 115/ edited by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch.
other author:	Dirsch, Verena M.
Description:	VII, 203 p. 144 illus., 42 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Pharmaceutical Sciences/Technology. -
Online resource:	https://doi.org/10.1007/978-3-030-64853-4
ISBN:	9783030648534

Progress in the Chemistry of Organic Natural Products 115
Progress in the Chemistry of Organic Natural Products 115[electronic resource] /edited by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch. - 1st ed. 2021. - VII, 203 p. 144 illus., 42 illus. in color.online resource. - Progress in the Chemistry of Organic Natural Products,1152192-4309 ;. - Progress in the Chemistry of Organic Natural Products,100.

Total Synthesis of Decanolides (Nonanolides) with a Special Focus on Olefin Metathesis -- From Plant to Patient: Thapsigargin -- Antileishmanial Activity of Lignans and Neolignans -- Cryptolepine as a Lead to new Antiprotozoal Agents -- Biologically Active Constituents from Plants of the Genus Xanthium.

This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.

ISBN: 9783030648534

Standard No.: 10.1007/978-3-030-64853-4doiSubjects--Topical Terms:

768561
Pharmaceutical Sciences/Technology.

LC Class. No.: QD415-436

Dewey Class. No.: 547

Progress in the Chemistry of Organic Natural Products 115
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