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Pharmacology of Potassium Channels

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Pharmacology of Potassium Channels/ edited by Nikita Gamper, KeWei Wang.
其他作者:	Wang, KeWei.
面頁冊數:	VIII, 545 p. 70 illus.online resource. :
Contained By:	Springer Nature eBook
標題:	Human Physiology. -
電子資源:	https://doi.org/10.1007/978-3-030-84052-5
ISBN:	9783030840525

Pharmacology of Potassium Channels
Pharmacology of Potassium Channels[electronic resource] /edited by Nikita Gamper, KeWei Wang. - 1st ed. 2021. - VIII, 545 p. 70 illus.online resource. - Handbook of Experimental Pharmacology,2671865-0325 ;. - Handbook of Experimental Pharmacology,224.

Comparison of K+ Channel families -- High-resolution structures of K+ channels -- Pharmacological approaches to studying potassium channels -- Cardiac K+ channels and channelopathies -- Cardiac hERG K+ channel as safety and pharmacological target -- Pharmacology of A-type K+ channels -- Kv7 channels and hyperexcitability disorders -- Pharmacological activation of neuronal voltage-gated Kv7/KCNQ/M-channels for potential therapy of epilepsy and pain -- Potassium channels in cancer -- Kir channel molecular physiology, pharmacology and therapeutic implications -- The pharmacology of ATP-sensitive K+ channels (KATP) -- Calcium-activated K+ channels (KCa) and therapeutic implications -- The Pharmacology of two-pore domain potassium channels -- Control of biophysical and pharmacological properties of potassium channels by ancillary subunits -- Peptide toxins targeting KV channels -- Therapeutic antibodies targeting potassium ion channels.

The aim of the present book is to comprehensively review current advances in understanding of genetics, structural biology, pharmacology of potassium channels and their roles in disease as well as to identify current gaps in knowledge. The ultimate goal is to provide a scientific foundation for better understanding of modulatory mechanisms and pharmacology of potassium channels and to use this understanding to drive future drug discovery. This book will be a must-have for academic and industrial scientists interested in physiology, pharmacology, pathology and structure-functional relationships of ion channels. The book will also be helpful for lecturers and students in the college and university classrooms, as well as for anyone interested in the state-of-the art in modern cell biology, physiology and pharmacology. .

ISBN: 9783030840525

Standard No.: 10.1007/978-3-030-84052-5doiSubjects--Topical Terms:

668349
Human Physiology.

LC Class. No.: RM1-950

Dewey Class. No.: 615

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520 $a The aim of the present book is to comprehensively review current advances in understanding of genetics, structural biology, pharmacology of potassium channels and their roles in disease as well as to identify current gaps in knowledge. The ultimate goal is to provide a scientific foundation for better understanding of modulatory mechanisms and pharmacology of potassium channels and to use this understanding to drive future drug discovery. This book will be a must-have for academic and industrial scientists interested in physiology, pharmacology, pathology and structure-functional relationships of ion channels. The book will also be helpful for lecturers and students in the college and university classrooms, as well as for anyone interested in the state-of-the art in modern cell biology, physiology and pharmacology. .
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