國立虎尾科技大學 |

Pharmacology of Potassium Channels

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Pharmacology of Potassium Channels/ edited by Nikita Gamper, KeWei Wang.
other author:	Gamper, Nikita.
Description:	VIII, 545 p. 70 illus.online resource. :
Contained By:	Springer Nature eBook
Subject:	Pharmacology. -
Online resource:	https://doi.org/10.1007/978-3-030-84052-5
ISBN:	9783030840525

Pharmacology of Potassium Channels
Pharmacology of Potassium Channels[electronic resource] /edited by Nikita Gamper, KeWei Wang. - 1st ed. 2021. - VIII, 545 p. 70 illus.online resource. - Handbook of Experimental Pharmacology,2671865-0325 ;. - Handbook of Experimental Pharmacology,224.

Comparison of K+ Channel families -- High-resolution structures of K+ channels -- Pharmacological approaches to studying potassium channels -- Cardiac K+ channels and channelopathies -- Cardiac hERG K+ channel as safety and pharmacological target -- Pharmacology of A-type K+ channels -- Kv7 channels and hyperexcitability disorders -- Pharmacological activation of neuronal voltage-gated Kv7/KCNQ/M-channels for potential therapy of epilepsy and pain -- Potassium channels in cancer -- Kir channel molecular physiology, pharmacology and therapeutic implications -- The pharmacology of ATP-sensitive K+ channels (KATP) -- Calcium-activated K+ channels (KCa) and therapeutic implications -- The Pharmacology of two-pore domain potassium channels -- Control of biophysical and pharmacological properties of potassium channels by ancillary subunits -- Peptide toxins targeting KV channels -- Therapeutic antibodies targeting potassium ion channels.

The aim of the present book is to comprehensively review current advances in understanding of genetics, structural biology, pharmacology of potassium channels and their roles in disease as well as to identify current gaps in knowledge. The ultimate goal is to provide a scientific foundation for better understanding of modulatory mechanisms and pharmacology of potassium channels and to use this understanding to drive future drug discovery. This book will be a must-have for academic and industrial scientists interested in physiology, pharmacology, pathology and structure-functional relationships of ion channels. The book will also be helpful for lecturers and students in the college and university classrooms, as well as for anyone interested in the state-of-the art in modern cell biology, physiology and pharmacology. .

ISBN: 9783030840525

Standard No.: 10.1007/978-3-030-84052-5doiSubjects--Topical Terms:

583819
Pharmacology.

LC Class. No.: RM1-950

Dewey Class. No.: 615

Pharmacology of Potassium Channels
LDR:03185nam a22004095i 4500 001 1052440
003 DE-He213
005 20210927122241.0
007 cr nn 008mamaa
008 220103s2021 sz | s |||| 0|eng d
020 $a 9783030840525 $9 978-3-030-84052-5
024 7 $a 10.1007/978-3-030-84052-5 $2 doi
035 $a 978-3-030-84052-5
050 4 $a RM1-950
072 7 $a MMG $2 bicssc
072 7 $a MED071000 $2 bisacsh
072 7 $a MKG $2 thema
082 0 4 $a 615 $2 23
245 1 0 $a Pharmacology of Potassium Channels $h [electronic resource] / $c edited by Nikita Gamper, KeWei Wang.
250 $a 1st ed. 2021.
264 1 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2021.
300 $a VIII, 545 p. 70 illus. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
490 1 $a Handbook of Experimental Pharmacology, $x 1865-0325 ; $v 267
505 0 $a Comparison of K+ Channel families -- High-resolution structures of K+ channels -- Pharmacological approaches to studying potassium channels -- Cardiac K+ channels and channelopathies -- Cardiac hERG K+ channel as safety and pharmacological target -- Pharmacology of A-type K+ channels -- Kv7 channels and hyperexcitability disorders -- Pharmacological activation of neuronal voltage-gated Kv7/KCNQ/M-channels for potential therapy of epilepsy and pain -- Potassium channels in cancer -- Kir channel molecular physiology, pharmacology and therapeutic implications -- The pharmacology of ATP-sensitive K+ channels (KATP) -- Calcium-activated K+ channels (KCa) and therapeutic implications -- The Pharmacology of two-pore domain potassium channels -- Control of biophysical and pharmacological properties of potassium channels by ancillary subunits -- Peptide toxins targeting KV channels -- Therapeutic antibodies targeting potassium ion channels.
520 $a The aim of the present book is to comprehensively review current advances in understanding of genetics, structural biology, pharmacology of potassium channels and their roles in disease as well as to identify current gaps in knowledge. The ultimate goal is to provide a scientific foundation for better understanding of modulatory mechanisms and pharmacology of potassium channels and to use this understanding to drive future drug discovery. This book will be a must-have for academic and industrial scientists interested in physiology, pharmacology, pathology and structure-functional relationships of ion channels. The book will also be helpful for lecturers and students in the college and university classrooms, as well as for anyone interested in the state-of-the art in modern cell biology, physiology and pharmacology. .
650 0 $a Pharmacology. $3 583819
650 0 $a Human physiology. $3 636012
650 0 $a Neurosciences. $3 593561
650 1 4 $a Pharmacology/Toxicology. $3 593882
650 2 4 $a Human Physiology. $3 668349
700 1 $a Gamper, Nikita. $e editor. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1357163
700 1 $a Wang, KeWei. $e editor. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1357164
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9783030840518
776 0 8 $i Printed edition: $z 9783030840532
776 0 8 $i Printed edition: $z 9783030840549
830 0 $a Handbook of Experimental Pharmacology, $x 0171-2004 ; $v 224 $3 1254015
856 4 0 $u https://doi.org/10.1007/978-3-030-84052-5
912 $a ZDB-2-SBL
912 $a ZDB-2-SXB
950 $a Biomedical and Life Sciences (SpringerNature-11642)
950 $a Biomedical and Life Sciences (R0) (SpringerNature-43708)