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Collagen Biografts for Tunable Drug Delivery

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Collagen Biografts for Tunable Drug Delivery/ by Rucha Joshi.
作者:	Joshi, Rucha.
面頁冊數:	XII, 107 p. 41 illus., 30 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Biomedical Engineering/Biotechnology. -
電子資源:	https://doi.org/10.1007/978-3-030-63817-7
ISBN:	9783030638177

Collagen Biografts for Tunable Drug Delivery
Joshi, Rucha.

Collagen Biografts for Tunable Drug Delivery[electronic resource] /by Rucha Joshi. - 1st ed. 2021. - XII, 107 p. 41 illus., 30 illus. in color.online resource. - SpringerBriefs in Applied Sciences and Technology,2191-5318. - SpringerBriefs in Applied Sciences and Technology,.

Introduction -- Creating Tunable Collagen Matrices - An Approach Inspired by In-Vivo Collagen Synthesis and Self-Assembly -- Application of Collagen Fibril Biografts for Enhancing Local Vascularization in an In-Vivo Chick Chorioallantoic Membrane (CAM) Model -- Appendix A: Type I Collagen Based Drug Delivery Formats -- Appendix B: State-of-the-Art Methods of Tuning Collagen Based Molecular Release.

This book reviews collagen-based biomaterials that have been applied broadly to tissue engineering and local drug delivery applications and lays out a landscape for developing a multifunctional biograft material from collagen polymers. The book also discusses current shortcomings in collagen based drug delivery opportunities, including poor mechanical properties, rapid proteolytic degradation, and cursory control over physical properties and molecular release profiles. Finally, a review of application of the collagen biograft materials for promoting neovascularization and tissue regeneration is presented, using examples of established in-vivo chicken egg chorioallantoic membrane (CAM) model. Use of heparin for affinity-based vascular endothelial growth factor (VEGF) retention in collagen constructs is also discussed for promoting neovascularization. Reviews state-of-the-art strategies for drug incorporation and retention in collagen ; Covers collagen based material applications for improving vascularization and tissue regeneration; Illustrates how to tailor collagen architecture for soft tissue engineering and controlled drug delivery.

ISBN: 9783030638177

Standard No.: 10.1007/978-3-030-63817-7doiSubjects--Topical Terms:

1068811
Biomedical Engineering/Biotechnology.

LC Class. No.: R856-857

Dewey Class. No.: 610.28

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