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Ferroptosis: Mechanism and Diseases

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Ferroptosis: Mechanism and Diseases/ edited by Andrés F. Florez, Hamed Alborzinia.
其他作者:	Alborzinia, Hamed.
面頁冊數:	IX, 140 p. 37 illus., 33 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Lipidology. -
電子資源:	https://doi.org/10.1007/978-3-030-62026-4
ISBN:	9783030620264

Ferroptosis: Mechanism and Diseases
Ferroptosis: Mechanism and Diseases[electronic resource] /edited by Andrés F. Florez, Hamed Alborzinia. - 1st ed. 2021. - IX, 140 p. 37 illus., 33 illus. in color.online resource. - Advances in Experimental Medicine and Biology,13012214-8019 ;. - Advances in Experimental Medicine and Biology,889.

Foreword -- Ferroptosis: Concepts and Definitions -- Overcoming Therapeutic Challenges for Pancreatic Ductal Adenocarcinoma with xCT inhibitors -- Iron Homeostasis and Metabolism: Two Sides of a Coin -- The Role of NCOA4-mediated Ferritinophagy in Ferroptosis -- Emerging Role for Ferroptosis in Infectious Diseases -- Small Molecule Regulators of Ferroptosis -- Necroptosis, The other main Caspase-Independent Cell Death.

This book focuses on the emerging role of ferroptosis in human diseases. It gives a detailed perspective on how to induce or suppress ferroptosis to treat challenging conditions such as infectious diseases, including COVID-19, tuberculosis, parasitic diseases and cancer. The book serves as a practical guide by providing a valuable collection of all currently known activators or inhibitors of ferroptosis. It will enable readers to choose molecules for experimental design for in vitro and in vivo studies of ferroptosis. Furthermore, this volume highlights the aspects of iron metabolism and its connection to ferritinophagy, a ferritin selective autophagy, with profound implications in neurodegenerative diseases such as Alzheimer, Parkinson, Huntington and ALS. Lastly, it describes necroptosis, another important form of cell death, along with its connections to human disorders and potential crosstalk with ferroptosis. While covering basic concepts, the book delves into mechanisms and modulation of ferroptosis for treating a wide variety of human diseases thus offering a valuable and informative resource for both, scientists and clinical researchers.

ISBN: 9783030620264

Standard No.: 10.1007/978-3-030-62026-4doiSubjects--Topical Terms:

681911
Lipidology.

LC Class. No.: RC261-271

Dewey Class. No.: 614.5999

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