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Biology and Treatment of Leukemia and Bone Marrow Neoplasms

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Biology and Treatment of Leukemia and Bone Marrow Neoplasms / edited by Vinod Pullarkat, Guido Marcucci.
other author:	Pullarkat, Vinod.
Description:	VIII, 196 p. 17 illus., 14 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Hematology. -
Online resource:	https://doi.org/10.1007/978-3-030-78311-2
ISBN:	9783030783112

Biology and Treatment of Leukemia and Bone Marrow Neoplasms
Biology and Treatment of Leukemia and Bone Marrow Neoplasms [electronic resource] /edited by Vinod Pullarkat, Guido Marcucci. - 1st ed. 2021. - VIII, 196 p. 17 illus., 14 illus. in color.online resource. - Cancer Treatment and Research,1812509-8497 ;. - Cancer Treatment and Research,165.

Advances in diagnosis and risk stratification of leukemias and bone marrow neoplasms -- Genetics and diagnostic approach to lymphoblastic leukemia -- Acute promyelocytic leukemia: update on risk stratification and treatment -- Current and emerging therapies for AML -- Current management and new developments in treatment of ALL -- Contemporary therapy of CML -- MDS: Pathogenesis and therapy -- Chronic lymphocytic leukemia: Biology and therapy -- Biology and current treatment of Myeloproliferative neoplasms -- Systemic Mastocytosis: Pathology and treatment -- Adoptive T-cell therapy and other novel immunotherapies for leukemia.

This book provides a concise update on current understanding of the biology of acute and chronic leukemias and other bone marrow neoplasms, including myelodysplastic and myeloproliferative disorders, and explores new and emerging treatments. There is a particular focus on the molecular abnormalities that are drivers of leukemia and on their detection by modern molecular techniques. Knowledge of the ways in which genomic and metabolic abnormalities in the hematologic neoplasms affect prognosis and treatment decision making is reviewed. Detailed attention is devoted to targeted therapies, including novel drugs, and to potential targets for future drug development. In addition, readers find in-depth discussion of cellular and antibody-based immunotherapies as well as the role of hematopoietic stem cell transplantation in the treatment of leukemias and bone marrow malignancies. The book is of special interest for hematologists, oncologists, and cancer researchers; it is also of value for hematology trainees and medical students.

ISBN: 9783030783112

Standard No.: 10.1007/978-3-030-78311-2doiSubjects--Topical Terms:

645254
Hematology.

LC Class. No.: RB45

Dewey Class. No.: 616.15

Biology and Treatment of Leukemia and Bone Marrow Neoplasms
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520 $a This book provides a concise update on current understanding of the biology of acute and chronic leukemias and other bone marrow neoplasms, including myelodysplastic and myeloproliferative disorders, and explores new and emerging treatments. There is a particular focus on the molecular abnormalities that are drivers of leukemia and on their detection by modern molecular techniques. Knowledge of the ways in which genomic and metabolic abnormalities in the hematologic neoplasms affect prognosis and treatment decision making is reviewed. Detailed attention is devoted to targeted therapies, including novel drugs, and to potential targets for future drug development. In addition, readers find in-depth discussion of cellular and antibody-based immunotherapies as well as the role of hematopoietic stem cell transplantation in the treatment of leukemias and bone marrow malignancies. The book is of special interest for hematologists, oncologists, and cancer researchers; it is also of value for hematology trainees and medical students.
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