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SARS-CoV-2 Spike Protein Convergent Evolution = Impact of Virus Variants on Efficacy of COVID-19 Therapeutics and Vaccines /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	SARS-CoV-2 Spike Protein Convergent Evolution/ by Daniele Focosi.
其他題名:	Impact of Virus Variants on Efficacy of COVID-19 Therapeutics and Vaccines /
作者:	Focosi, Daniele.
面頁冊數:	XIII, 136 p. 11 illus., 2 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Microbial Genetics and Genomics. -
電子資源:	https://doi.org/10.1007/978-3-030-87324-0
ISBN:	9783030873240

SARS-CoV-2 Spike Protein Convergent Evolution = Impact of Virus Variants on Efficacy of COVID-19 Therapeutics and Vaccines /
Focosi, Daniele.

SARS-CoV-2 Spike Protein Convergent EvolutionImpact of Virus Variants on Efficacy of COVID-19 Therapeutics and Vaccines /[electronic resource] :by Daniele Focosi. - 1st ed. 2021. - XIII, 136 p. 11 illus., 2 illus. in color.online resource. - SpringerBriefs in Microbiology,2191-5393. - SpringerBriefs in Microbiology,.

Chapter 1. Why the Spike protein is relevant for COVID19 therapeutics -- Chapter 2. SARS-CoV-2 variants -- Chapter 3. Conclusion.

This book reviews the current knowledge of the globally circulating SARS-CoV-2 variants, highlights their distinct genetic characteristics and associated conformational changes in the viral spike protein, and profoundly discusses the mechanisms of convergent evolution that led to the rise of these mutated strains at different geographic regions during the Covid-19 pandemic. Furthermore, the book explores how these variants do and may impact the efficacy of established neutralizing antibody-based (nAb) vaccines and therapeutics by analysing latest in vivo and in vitro clinical data. Finally, the author discusses ways on how nAb Covid-19 treatment derived immune escape of SARS-CoV-2 could be minimized in the future.

ISBN: 9783030873240

Standard No.: 10.1007/978-3-030-87324-0doiSubjects--Topical Terms:

668641
Microbial Genetics and Genomics.

LC Class. No.: QR355-502

Dewey Class. No.: 616.9101

SARS-CoV-2 Spike Protein Convergent Evolution = Impact of Virus Variants on Efficacy of COVID-19 Therapeutics and Vaccines /
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