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Mixed-Mode Chromatography = Principles, Methods, and Applications /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Mixed-Mode Chromatography/ by Qian-Hong Wan.
Reminder of title:	Principles, Methods, and Applications /
Author:	Wan, Qian-Hong.
Description:	XIII, 482 p. 216 illus., 65 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Pharmaceutical technology. -
Online resource:	https://doi.org/10.1007/978-981-16-5485-5
ISBN:	9789811654855

Mixed-Mode Chromatography = Principles, Methods, and Applications /
Wan, Qian-Hong.

Mixed-Mode ChromatographyPrinciples, Methods, and Applications /[electronic resource] :by Qian-Hong Wan. - 1st ed. 2021. - XIII, 482 p. 216 illus., 65 illus. in color.online resource.

Chapter 1.Historical Perspectives -- Chapter 2.Theoretical Background -- Chapter 3.Modes of Chromatographic Separation -- Chapter 4.Chromatographic Matrices -- Chapter 5.Ligand Design -- Chapter 6.Retention Mechanisms -- Chapter 7.Stationary Phases -- Chapter 8.Mobile Phases and Elution -- Chapter 9.Method Development -- Chapter 10.Applications in Biopharmaceutical Processing. .

The book is about the technology and application of Mixed-mode chromatography (MMC). Unlike conventional single-mode HPLC, which resolves the analytes primarily based on their ionic or hydrophobic properties, MMC employs multifunctional stationary phases to exploit at least two modes of interactions (i.e., ionic and hydrophobic) with the analytes and as such often provides resolution that far exceeds that observed with a single-mode process. Over the past two decades, MMC has developed into an important analytical and purification tool in a number of applications in pharmaceutical and biotechnology industries. The technique has been used widely for the analyses of nucleic acids, amino acids, peptides, proteins, glycoproteins, carbohydrates, antibiotics, vaccines, and other products. The purpose of this book is to present a comprehensive survey of mixed-mode chromatography and is intended as a reference guide for graduate students and experienced scientists in pharmaceutical and biotechnology disciplines wishing to gain a deep understanding of this continuously evolving technology. .

ISBN: 9789811654855

Standard No.: 10.1007/978-981-16-5485-5doiSubjects--Topical Terms:

557391
Pharmaceutical technology.

LC Class. No.: RS380

Dewey Class. No.: 615.19

Mixed-Mode Chromatography = Principles, Methods, and Applications /
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505 0 $a Chapter 1.Historical Perspectives -- Chapter 2.Theoretical Background -- Chapter 3.Modes of Chromatographic Separation -- Chapter 4.Chromatographic Matrices -- Chapter 5.Ligand Design -- Chapter 6.Retention Mechanisms -- Chapter 7.Stationary Phases -- Chapter 8.Mobile Phases and Elution -- Chapter 9.Method Development -- Chapter 10.Applications in Biopharmaceutical Processing. .
520 $a The book is about the technology and application of Mixed-mode chromatography (MMC). Unlike conventional single-mode HPLC, which resolves the analytes primarily based on their ionic or hydrophobic properties, MMC employs multifunctional stationary phases to exploit at least two modes of interactions (i.e., ionic and hydrophobic) with the analytes and as such often provides resolution that far exceeds that observed with a single-mode process. Over the past two decades, MMC has developed into an important analytical and purification tool in a number of applications in pharmaceutical and biotechnology industries. The technique has been used widely for the analyses of nucleic acids, amino acids, peptides, proteins, glycoproteins, carbohydrates, antibiotics, vaccines, and other products. The purpose of this book is to present a comprehensive survey of mixed-mode chromatography and is intended as a reference guide for graduate students and experienced scientists in pharmaceutical and biotechnology disciplines wishing to gain a deep understanding of this continuously evolving technology. .
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