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Gene Therapy of Cancer = Methods and Protocols /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Gene Therapy of Cancer/ edited by Wolfgang Walther.
Reminder of title:	Methods and Protocols /
other author:	Walther, Wolfgang.
Description:	XI, 342 p. 65 illus., 47 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Cancer. -
Online resource:	https://doi.org/10.1007/978-1-0716-2441-8
ISBN:	9781071624418

Gene Therapy of Cancer = Methods and Protocols /
Gene Therapy of CancerMethods and Protocols /[electronic resource] :edited by Wolfgang Walther. - 3rd ed. 2022. - XI, 342 p. 65 illus., 47 illus. in color.online resource. - Methods in Molecular Biology,25211940-6029 ;. - Methods in Molecular Biology,2540.

Brief Introduction to Current Cancer Gene Therapy -- Minicircles for CAR T Cell Production by Sleeping Beauty Transposition - A Technological Overview -- Generation of CAR-T Cells with Sleeping Beauty Transposon Gene Transfer -- Generation of Redirected Engineered Human Chimeric Antigen Receptor (CAR) T cells -- TCR- and CAR-engineering of Primary Human T cells -- TCR Gene Therapy for Cancer -- Gene Gun Her2/neu DNA Vaccination: Evaluation of Vaccine Efficacy in a Syngeneic Her2/neu Mouse Tumor Model -- Construction of Minicircle Suicide Genes Coding for Ribosome-Inactivating Proteins -- Claudin-targeted Suicide Gene Therapy for Claudin-Overexpressing Tumor Cells by Using Modified Clostridium Perfringens Enterotoxin (CPE) -- Bioengineered RNA Therapy in Patient-Derived Organoids and Xenograft Mouse Models -- Application of Transcription Factor Decoy Oligodeoxynucleotides (ODNs) for Cancer Therapy -- NK Cell Effector Functions and Bystander Tumor Cell Killing in Immunovirotherapy -- A qPCR-based Method for Quantification of Replication Competent Adenovirus (RCA) in Conditionally Replicating Oncolytic Adenoviruses -- Visualized Cancer Immunotherapy with Engineered Salmonella typhimurium -- CANCER Gene Therapy: Development and Production Of Lentiviral Vectors For Gene Therapy -- Capillary Gel Electrophoresis (CGE) for Quality Control of Plasmid DNA in Gene Therapy: quality control of 20-years stored GMP-grade Plasmid DNA -- Efficient Generation of Superior Dumbbell-Shaped Non-viral DNA Delivery Vectors Using 1-2-3 Gap-primer PCR.

This third edition provides new and updated chapters on gene therapeutic strategies of cancer. Chapters guide readers through suicide and oncolytic gene therapy, gene replacement and gene suppression therapy, vector development and refinement, immunogene therapy, TCR and CAR engineering, tumor vaccination using DNA or RNA vaccines, and antitumoral immune stimulation at different levels. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Gene Therapy of Cancer: Methods and Protocols, Third Edition aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.

ISBN: 9781071624418

Standard No.: 10.1007/978-1-0716-2441-8doiSubjects--Topical Terms:

581034
Cancer.

LC Class. No.: RC261-271

Dewey Class. No.: 571.978

Gene Therapy of Cancer = Methods and Protocols /
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