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Green Chemistry in Drug Discovery = From Academia to Industry /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Green Chemistry in Drug Discovery/ edited by Paul F. Richardson.
Reminder of title:	From Academia to Industry /
other author:	Richardson, Paul F.
Description:	XVI, 617 p. 609 illus., 19 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Pharmacology. -
Online resource:	https://doi.org/10.1007/978-1-0716-1579-9
ISBN:	9781071615799

Green Chemistry in Drug Discovery = From Academia to Industry /
Green Chemistry in Drug DiscoveryFrom Academia to Industry /[electronic resource] :edited by Paul F. Richardson. - 1st ed. 2022. - XVI, 617 p. 609 illus., 19 illus. in color.online resource. - Methods in Pharmacology and Toxicology,1940-6053. - Methods in Pharmacology and Toxicology,.

Green Synthesis of Common Heterocycles -- Greener Methods for Amide Bond Synthesis -- Mitsunobu Reactions in Medicinal Chemistry and Development of Practical Modifications -- Direct Nucleophilic Substitution of Alcohols by Brønsted or Lewis Acids Activation: An Update -- Friedel-Crafts Reactions -- Ionic Liquids: Design and Applications -- Designing Efficient Cascade Reactions in Drug Discovery -- Multicomponent Synthesis: Cohesive Integration of Green Chemistry Principles -- Direct C–H Functionalization Approaches to Pharmaceutically Relevant Molecules -- C–H Activation with Photoredox Catalysis -- In Situ Protecting Groups for Chemoselective Transformations -- Expanding the Biocatalysis Toolbox -- New Directions in Coupling Chemistry -- Flow Chemistry as an Enabling Technology for Synthetic Organic Chemistry -- Reaction Optimization: A High-Throughput Experimentation Approach -- Radiopharmaceutical Discovery with 11CO2-Fixation Methods Inspired by Green Chemistry.

This detailed book highlights several emerging areas in the implementation of green chemistry in medicinal chemistry drug discovery with a specific focus on their application to the expeditious discovery of new biologically active entities. Divided into three sections, the collection explores greener approaches to chemical transformations that are both prevalent and have been highlighted as challenging within the pharmaceutical industry, overall synthetic strategy, as well as the implementation and impact of a range of enabling technologies within medicinal chemistry. As a volume of the Methods in Pharmacology and Toxicology series, chapters provide the kind of key insight that can guide researchers toward greater success in the lab. Authoritative and practical, Green Chemistry in Drug Discovery: From Academia to Industry provides both a fundamental insight into the progress that has been made as well as some of the challenges that still exist for these techniques to be effectively implemented in the drug discovery process in a routine manner.

ISBN: 9781071615799

Standard No.: 10.1007/978-1-0716-1579-9doiSubjects--Topical Terms:

583819
Pharmacology.

LC Class. No.: RM300-666

Dewey Class. No.: 615

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