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Macropinocytosis = Functions and Mechanisms /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Macropinocytosis/ edited by Cosimo Commisso.
其他題名:	Functions and Mechanisms /
其他作者:	Commisso, Cosimo.
面頁冊數:	XI, 224 p. 28 illus. in color.online resource. :
Contained By:	Springer Nature eBook
標題:	Biomedical Research. -
電子資源:	https://doi.org/10.1007/978-3-030-94004-1
ISBN:	9783030940041

Macropinocytosis = Functions and Mechanisms /
MacropinocytosisFunctions and Mechanisms /[electronic resource] :edited by Cosimo Commisso. - 1st ed. 2022. - XI, 224 p. 28 illus. in color.online resource. - Subcellular Biochemistry,982542-8810 ;. - Subcellular Biochemistry,71.

Part 1: Functions of Macropinocytosis -- Chapter 1: Functional Diversity of Macropinocytosis -- Chapter 2: Macropinocytosis and Cancer: From Tumor Stress to Signaling Pathways -- Chapter 3: The amoebal model for micropinocytosis -- Chapter 4: Extracellular ATP and macropinocytosis -- Chapter 5: Macropinocytosis and Cell Migration: Don't drink an drive -- Chapter 6: Macropinocytosis in phagocyte function and immunity -- Part 2: Signaling Mechanisms Driving Macropinocytosis -- Chapter 7: Roles of 3' Phosphoinositides in Macropinocytosis -- Chapter 8: Signaling pathways that regulate macropinocytosis in mammalian cells -- Chapter 9: Wnt, GSK3 and Macropinocytosis -- Chapter 10: Kras addiction promotes cancer cell adapation in harsh microenvironment through micropinocytosis -- Chapter 11: Kras-independent macropinocytosis in pancreatic cancer.

This book presents the functions and mechanisms of macropinocytosis, an actin-driven endocytic uptake process. Key points, including the evolutionary origins of macropinocytosis and major signaling pathways that regulate this uptake mechanism, are highlighted. A wide-array of functions of macropinocytosis are described, including cellular metabolism, cell death, cell migration and antigen presentation. Macropinocytosis has recently been recognized as a critical pathway in disease pathology and treatment. Therefore, a broad overview of macropinocytosis will benefit clinicians, as well as translational and basic research scientists. Moreover, as one of the main clathrin-independent endocytic routes, compiling all the critical information about macropinocytosis in one collection, this book will also be helpful to educators and their students.

ISBN: 9783030940041

Standard No.: 10.1007/978-3-030-94004-1doiSubjects--Topical Terms:

643481
Biomedical Research.

LC Class. No.: QH573-671

Dewey Class. No.: 571.6

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