國立虎尾科技大學 |

The centrosome and its functions and dysfunctions

Record Type:	Language materials, printed : Monograph/item
Title/Author:	The centrosome and its functions and dysfunctions/ by Heide Schatten.
Author:	Schatten, Heide.
Published:	Cham :Springer International Publishing : : 2022.,
Description:	vii, 111 p. :ill. (some col.), digital ; : 24 cm.;
Contained By:	Springer Nature eBook
Subject:	Centrosomes. -
Online resource:	https://doi.org/10.1007/978-3-031-20848-5
ISBN:	9783031208485

The centrosome and its functions and dysfunctions
Schatten, Heide.

The centrosome and its functions and dysfunctions[electronic resource] /by Heide Schatten. - Cham :Springer International Publishing :2022. - vii, 111 p. :ill. (some col.), digital ;24 cm. - Advances in anatomy, embryology and cell biology,v. 2352192-7065 ;. - Advances in anatomy, embryology and cell biology ;201..

Cell and Molecular Biology of Centrosome Structure and Function -- The centrosome Cycle within the cell cycle -- Centrosome as center for proteolytic activity and dysfunctions associated with pathogenesis of human disease -- Centrosome dysfunctions in cancer -- Virus exploitation of centrosomes -- Centrosomes in reproduction -- Transition from centrosomal to non-centrosomal microtubule organization during cellular polarization -- External and environmental effects on Centrosomes -- Centrosomes and centrosome equivalents in other systems -- Non-centrosomal microtubule organization in plant cells.

The book provides a comprehensive overview of classic and modern approaches of centrosome research, including new aspects of centrosome functions focusing on primary cilia and their implications in numerous diseases. In addition, several chapters raise awareness of centrosomes in areas that have not yet fully considered the centrosome as an organelle that impacts other organelle functions directly or indirectly. It further relates centrosome functions to other research areas such as aging and stem cell research. Since its discovery almost 150 years ago the centrosome is increasingly being recognized as a most impactful organelle for its role, not only as primary microtubule organizing center (MTOC) but also as a major communication center for signal transduction pathways and as a center for proteolytic activities. Its significance for cell cycle regulation has been well studied and we now also know that centrosome dysfunctions are implicated in numerous diseases and disorders including cancer, cystic diseases of the kidney, liver fibrosis, cardiac defects, obesity and several other diseases and disorders. This new volume reviews the latest advances in the field and provides valuable background information that is readily understandable for the newcomer and the experienced centrosome researcher alike. Due to the interdisciplinary of the subject, it is a valuable resource for researchers and clinicians working in biomedical research, cell biology, cancer biology, reproduction and developmental biology, neuroscience and stem cell research.

ISBN: 9783031208485

Standard No.: 10.1007/978-3-031-20848-5doiSubjects--Topical Terms:

883878
Centrosomes.

LC Class. No.: QH597

Dewey Class. No.: 571.65

The centrosome and its functions and dysfunctions
LDR:03228nam a2200337 a 4500 001 1097643
003 DE-He213
005 20221216201324.0
006 m d
007 cr nn 008maaau
008 230419s2022 sz s 0 eng d
020 $a 9783031208485 $q (electronic bk.)
020 $a 9783031208478 $q (paper)
024 7 $a 10.1007/978-3-031-20848-5 $2 doi
035 $a 978-3-031-20848-5
040 $a GP $c GP
041 0 $a eng
050 4 $a QH597
072 7 $a PSF $2 bicssc
072 7 $a SCI049000 $2 bisacsh
072 7 $a PSF $2 thema
082 0 4 $a 571.65 $2 23
090 $a QH597 $b .S312 2022
100 1 $a Schatten, Heide. $3 677613
245 1 4 $a The centrosome and its functions and dysfunctions $h [electronic resource] / $c by Heide Schatten.
260 $a Cham : $c 2022. $b Springer International Publishing : $b Imprint: Springer,
300 $a vii, 111 p. : $b ill. (some col.), digital ; $c 24 cm.
490 1 $a Advances in anatomy, embryology and cell biology, $x 2192-7065 ; $v v. 235
505 0 $a Cell and Molecular Biology of Centrosome Structure and Function -- The centrosome Cycle within the cell cycle -- Centrosome as center for proteolytic activity and dysfunctions associated with pathogenesis of human disease -- Centrosome dysfunctions in cancer -- Virus exploitation of centrosomes -- Centrosomes in reproduction -- Transition from centrosomal to non-centrosomal microtubule organization during cellular polarization -- External and environmental effects on Centrosomes -- Centrosomes and centrosome equivalents in other systems -- Non-centrosomal microtubule organization in plant cells.
520 $a The book provides a comprehensive overview of classic and modern approaches of centrosome research, including new aspects of centrosome functions focusing on primary cilia and their implications in numerous diseases. In addition, several chapters raise awareness of centrosomes in areas that have not yet fully considered the centrosome as an organelle that impacts other organelle functions directly or indirectly. It further relates centrosome functions to other research areas such as aging and stem cell research. Since its discovery almost 150 years ago the centrosome is increasingly being recognized as a most impactful organelle for its role, not only as primary microtubule organizing center (MTOC) but also as a major communication center for signal transduction pathways and as a center for proteolytic activities. Its significance for cell cycle regulation has been well studied and we now also know that centrosome dysfunctions are implicated in numerous diseases and disorders including cancer, cystic diseases of the kidney, liver fibrosis, cardiac defects, obesity and several other diseases and disorders. This new volume reviews the latest advances in the field and provides valuable background information that is readily understandable for the newcomer and the experienced centrosome researcher alike. Due to the interdisciplinary of the subject, it is a valuable resource for researchers and clinicians working in biomedical research, cell biology, cancer biology, reproduction and developmental biology, neuroscience and stem cell research.
650 0 $a Centrosomes. $3 883878
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
830 0 $a Advances in anatomy, embryology and cell biology ; $v 201. $3 881442
856 4 0 $u https://doi.org/10.1007/978-3-031-20848-5
950 $a Biomedical and Life Sciences (SpringerNature-11642)